Coronary flow after thrombolysis.
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Biomedical subjects
Publications and source records attributed to P Zambelli.
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In nine patients (pts.) with recurrent SVT, we have performed a combined electrophysiological and hemodynamic study. Five pts. showed reciprocating nodal tachycardia and 4 pts. reentry tachycardia associated with WPW syndrome (2 with Kent bypass tract and 2 with James bypass tract). Hemodynamic parameters were recorded during sinus rhythm (SR), atrial (AP) and ventricular pacing (VP) and following the initiation of SVT. The arrhythmia was induced by rapid atrial pacing or with atrial or ventricular premature stimuli. Hemodynamic data were then compared. Our results point out a greater hemodynamic deterioration during SVT than during AP or sinus tachycardia at similar rates. We have often observed in SVT, and constantly in A-V nodal reentrant (AVN) cases, the appearance of giant waves in the right and left atrium. This finding confirms hypothesis of the primary role of the changes in atrioventricular contraction sequence during SVT, especially in AVN tachycardias, with subsequent reduction in stroke volume and cardiac output.
The occurrence of a Kaposi sarcoma during the course of a therapy for a pemphigus vulgaris is reported. Only five such associations have been previously described in the literature. On the other hand, several works have reported simultaneous occurrence of a Kaposi sarcoma with anomalies of the immune or lymphoïd systems (lymphoma, Hodgkin disease, Waldenström disease, mycosis fongoïdes. Hypothesis concerning the Kaposi sarcoma genesis can be suggested on the basis of these observations and remain to be confirmed.
Atropine sulfate 0.04 mg/Kg i.v. and propranolol 0.2 mg/Kg i.v. were administered to patients with SSS in an attempt to determine intrinsic heart rate (IHR). Sinus node recovery time (SNRT) was determined before and after autonomic sympathetic and parasympathetic blockade. This method could distinguish SSS patients in two groups: group I was composed of patients with extrinsic sinus node dysfunction, group II was composed of patients with intrinsic sinus node dysfunction. We conclude that this differentiation is of great importance for clinical-prognostic evaluation and therapeutic program in SSS.
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