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Biomedical subjects

P YEKUTIEL

Publications and source records attributed to P YEKUTIEL.

12 recordsLinked to original sources

Epidemiology of poliomyelitis in Israel, 1952-59, with evaluation of Salk vaccination during a three-year period.

The epidemic of poliomyelitis which occurred in Israel in 1958 among a population a large proportion of which had received inactivated Salk-type vaccine aroused great interest. This was the first time a vaccinated infant population had been exposed to a severe epidemic and thus afforded the first opportunity to determine whether or not vaccination afforded a high degree of protection in this age-group. The authors report on the observations made.While the vaccine conferred some protection, this was not of so high a degree as had been expected from experience elsewhere in older children. This partial failure may be explained in part by the use in the earlier vaccination campaigns of vaccines of lower potency than is now current and perhaps by the fact that many vaccinations were performed intradermally.No very exact measure of the protection conferred can be given. For some groups the figures are too small for statistical validity; for others, it is not possible to distinguish between the effect of vaccine and that of age, the latter possibly being the more important factor.

Child↗

Problems of epidemiology in malaria eradication.

With an increasing number of malaria eradication programmes approaching or entering the consolidation phase, the epidemiological features of disappearing malaria are getting better known and defined. At the same time, the old classical methods of measuring malaria prevalence have become inadequate and new methods for the epidemiological assessment of the progress of eradication are being developed.In this article the new methods of assessment and epidemiological and statistical criteria for discontinuing residual spraying and for the stability of consolidation are discussed on the basis of field experience in several countries during the past two or three years. Some prominent epidemiological features of malaria at reduced levels of transmission are described, special attention being given to the role of the asymptomatic carrier in malaria eradication.

Humans↗

Poliomyelitis outbreak in Israel, 1950-1.

The epidemicity of poliomyelitis in Israel since 1950 is reviewed, and the influence of the mass immigration which took place between 1948 and 1952 is discussed. Age distribution and attack-rates among Arabs, among Jewish population-groups originating in different countries, and among old residents and new immigrants, are examined. It is suggested that the change from endemicity to epidemicity of the disease may have been due to general overcrowding during the pre-epidemic period, and to enhanced circulation of virus (type 1), and a resulting increase in its pathogenicity.

Age Distribution↗