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Biomedical subjects

P Whitehead

Publications and source records attributed to P Whitehead.

29 records · Page 2Linked to original sources
PubMed1991

Revascularization of the lower extremity with omentum.

The use of the omental graft with multiple level arterial anastomoses may prove useful for salvaging the severely ischemic lower limb. Because the long-term results of full free omental grafts may depend on neovascularization of the omentum from the surrounding tissue, the technique described here should be utilized only in those patients who are not suitable candidates for other procedures.

Anastomosis, Surgical↗
PubMed1990

Western blot analysis of the antigen in pemphigoid gestationis.

Using an immunoblotting technique, sera from 25 patients with pemphigoid gestationis were examined and tested against epidermal and dermal extracts of normal skin. The major antigen recognized by seven patients' sera was a molecule of 180 kDa, pemphigoid gestationis antigen, extractable only from the epidermis. Sera from 18 patients with bullous pemphigoid were studied as positive controls and the major antigen recognized was a larger molecule of 220 kDa. There was some degree of shared recognition of antigens with three patients with pemphigoid gestationis recognizing the 220 kDa bullous pemphigoid antigen. In addition one bullous pemphigoid serum recognized the 180 kDa pemphigoid gestationis antigen. The dominant pemphigoid gestationis antigen, however, differs from bullous pemphigoid antigen.

Autoantigens↗
PubMed1984

Nucleotide sequence of the VP1 gene of the foot-and-mouth disease virus strain A Venceslau.

The VP1 coat protein of FMDV strain A Venceslau (Aven) consists of 213 amino acid residues. Serum neutralization tests demonstrated that strain Aven is closely related to strain A Argentina/79 (A79) but significantly different from strain A24Cruzeiro (A24). There is a strong correlation between the amino acid sequences and the serological data. Nucleotide and amino acid sequence analyses of VP1 showed that serologically related viruses (Aven and A79) differ less in this region of the genome than those of serologically distinct viruses (Aven vs. A24). The most significant variation between Aven and A24 occurs at amino acid positions 43 to 46, in which all four residues are different.

Amino Acid Sequence↗
PubMed1982

Fossil mammals and artefacts from the Middle Awash Valley, Ethiopia.

A review of fossil mammalian faunas from the Middle Awash indicates they span most of the later Neogene and document evolutionary change in several mammalian groups, especially Primates, Proboscidea and Artiodactyla. Oldowan artefacts first appear in the late Pliocene, while Acheulian and later industries and apparent occupation sites occur in Pleistocene beds.

Animals↗