Biomedical subjects
P Ward Booth
Publications and source records attributed to P Ward Booth.
Technique for harvesting tibial cancellous bone modified for use in children.
We present modifications of the technique of harvesting adult tibial cancellous bone that enables its safe and reliable use in children. We studied 15 children undergoing secondary grafting of alveolar clefts radiographically and clinically and compared them with a similar group of children who had bone harvested from the iliac crest. Duration of hospital stay (mean 1, range 1-2 compared with 3, range 2-4) analgesic requirements (duration 1-4 days compared with 1-3 weeks) were all considerably less when bone was taken from the proximal tibia and mobility was considerably improved (able to walk on day 1 compared with restricted walking for 1-3 weeks.
Serum alkaline deoxyribonuclease in oral cancer and premalignant lesions.
Serum activities of alkaline deoxyribonuclease were assayed in 61 patients with oral squamous cell carcinoma, 23 with oral keratosis (a possible premalignant lesion), and 48 matched controls. The activity of alkaline deoxyribonuclease was significantly greater in patients with oral cancer than in either those with oral keratosis, or controls. The activities of deoxyribonucleases in keratosis were greater than in controls but not at a significant difference.