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Biomedical subjects

P Vogelbach

Publications and source records attributed to P Vogelbach.

29 records · Page 2Linked to original sources

[Radiation-sparing intramedullary nailing with a radiolucent drilling system].

The indications for intramedullary fixation of tibial and femoral shaft fractures markedly increased by the introduction of interlocking techniques. Distal interlocking however remains a major problem although a variety of different aiming devices have been proposed. To reduce the radiation exposure both of the surgeon and the patient the AO has produced a radiolucent drive which allows easy aiming and drilling with a minimum of X-ray exposure.

Femoral Fractures↗

[Splitting liver transplantation. Orthotopic liver transplantation in two recipients with a single donor liver].

Surgical reduction of donor livers to treat small children has been performed successfully in several centers. While this procedure improves the allocation of livers, it does not increase the organ supply. Since either lobe can be used in preparing a reduced-size graft, both lobes can become grafts, if acceptable vascular pedicles and bile ducts can be established for each one. We report and demonstrate a technique, in which a donor liver has been split and was used to transplant in two recipients.

Anastomosis, Surgical↗

[Preservation of donor livers with University of Wisconsin solution].

The University of Wisconsin-solution extends the cold storage time of liver grafts over 20 hours. The early function is equal or better than with Eurocollins solution. Due to the extended preservation time, logistical advantages are present. However, deliberate extension of cold ischemia over the limit of 20 to 24 hours seems not yet indicated, since primary non-functioning grafts have a higher incidence after extended preservation.

Adenosine↗

Transplantation of two patients with one liver. Analysis of a preliminary experience with 'split-liver' grafting.

Surgical reduction of donor livers to treat small children has been performed successfully in several centers. While this procedure improves the allocation of livers, it does not increase the organ supply. We have extended reduced-size orthotopic liver transplantation (OLT) to treat 18 patients with 9 livers, accounting for 26% of our transplants during a 10-month period and have evaluated the results. In 18 split liver OLTs, patient survival was 67% and graft survival was 50%. In comparison, for 34 patients treated with full-size OLT during the same period, patient survival was 84% (p = 0.298) and graft survival was 76% (p = 0.126). Biliary complications were significantly more frequent in split grafts, occurring in 27%, as compared to 4% in full-sized grafts (p = 0.017). Primary nonfunction (4% versus 5.5%) and arterial thrombosis (6% versus 9%) occurred with similar frequency in split and full-size OLT (p = not significant). These results demonstrated that split-liver OLT is feasible and could have a substantial impact in transplant practice. We believe that biliary complications can be prevented by technical improvements and that split-liver OLT will improve transplant therapy by making more livers available.

Adult↗

Successful hepatic transplantation in congenital absence of recipient portal vein.

The first case of hepatic transplantation in a patient with congenital absence of the portal vein (CAPV) is reported. A 10-year-old girl with biliary atresia and CAPV underwent successful hepatic transplantation and has normal liver function 9 months after transplantation. This case is only the seventh reported case of CAPV. Patients with CAPV commonly have additional liver anomalies, cardiac and inferior vena cava anomalies, and polysplenia. Surprisingly, hepatic encephalopathy is not a prominent feature in patients with CAPV despite systemic drainage of mesenteric venous blood. CAPV should not be considered a contraindication to hepatic transplantation.

Abnormalities, Multiple↗

[Shunt surgery with reference to indications for liver transplantation].

Sclerotherapy and protosystemic shunt surgery are established procedures for treating bleeding esophageal varices. Liver transplantation (OLT) has not yet been established as primary therapy of portal hypertension. In a series of 43 patients with uncontrollable bleeding, shunt surgery was employed in 26 patients with contra-indications to OLT and in 2 whose liver disease had not progressed. In the remaining 15 patients, OLT was performed in urgent (n = 8) and emergency settings (n = 7). The results obtained indicate that immediate shunting in nontransplant candidates results in one-year survival for 67-83% of Child's class A or B Patients and only 42% Child's C category regardless of the type of shunt procedure performed. In transplant candidates with a similar risk status (Child's B and C) 5 of 8 patients receiving an urgent transplant and 4 of 7 patients receiving emergency OLT during active bleeding survived for one year or more. These results indicate that bleeding varices can be treated successfully by OLT.

Esophageal and Gastric Varices↗

[Prospective assessment study of 586 consecutive continuous, single layer, extra-mucosal colon anastomoses].

22 Swiss hospitals participated in a multicenter trial testing the acceptance and safety of a continuous single layer end-to-end colonic anastomosis for all mobile segments of the colon, i.e. above the peritoneal reflexion. No cases in elective or emergency surgery have been excluded. During one year other techniques have been totally dropped from the participating centers. Among 545 patients with 586 anastomoses in all centers participating during one full year there were only two clinical leaks. All participating hospitals have after this one year continued to use this technique. Many have expanded it to small bowel and gastric surgery.

Aged↗

Single-layer end-on continuous suture of colonic anastomoses.

The single-layer end-on continuous suture technique for intestinal anastomoses on mobile intraperitoneal bowel segments is at least as safe and probably safer than a corresponding single-layer interrupted suture technique. Although the evaluation of this technique included a substantial number of surgeons who were performing their first anastomosis or who contributed only a single one to the series in a teaching university setting, there were no instances of clinical leak among 143 consecutive colonic anastomoses. Furthermore, 27 percent of the operations were performed as emergencies, thus optimal bowel preparation was lacking. The anastomosis time is distinctly shorter than the time needed for an interrupted single-layer technique, and contamination of the operative field is reduced to a minimum. The anastomosis is extremely simple, comfortable to perform, and reliable.

Anastomosis, Surgical↗

Cervical lymphadenitis--a rare case of focal listeriosis.

Cervical lymphadenopathy is a condition with a broad differential diagnosis. Malignant tumors, allergic reactions, autoimmune diseases as well as various infectious agents can be the cause. We report the case of a 75-year-old man who had a cervical lymphadenopathy without symptoms of infection. The draining lymph nodes were excised. Histology revealed a granulomatous abscess and culture yielded pure growth of Listeria monocytogenes. Because food is occasionally contaminated with L. monocytogenes, the pathogenesis of this condition may be similar to that of lymph node tuberculosis.

Aged↗