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Biomedical subjects

P Vock

Publications and source records attributed to P Vock.

At least 127 records · Page 7Linked to original sources
PubMed1981

[Computer tomography for staging of bronchial carcinomas (author's transl)].

Thoracic computer tomography was performed in 135 patients with bronchial carcinoma. 1) In 90% a precise estimate of the extent of the primary tumour was possible. The computer tomogram was markedly superior to traditional radiological methods in showing invasion of the chest wall and mediastinum. 2) Regional lymph node metastases were demonstrated correctly in 82%. Lymph node enlargement must be differentiated from that due to benign causes. 3) In 92%, the extent of distal metastases could be correctly established. The computer tomogram makes it possible to avoid exploratory thoracotomy if there is transpleural invasion, extensive mediastinal lymph node metastasation or distant metastasation. Where there is doubt, computer tomography-guided needle aspiration should be employed.

Adenocarcinoma↗
PubMed1981

[Computed tomography of the mediastinum (author's transl)].

In a review study, the diagnostic possibilities of modern CT apparatus with scanning times of some seconds were demonstrated. The two main advantages-1) imaging of axial body sections without superimposition and 2) the high resolution of tissue densities-guarantee on the one hand possibility of diagnosis and three dimensional localization of tumors not afforded by conventional radiographic methods, and on the other hand definite qualitative analysis of different disease patterns. This results primarily in precise clarification of both neoplastic and inflammatory mediastinal masses, secondly provides a non-invasive route of investigation of lipomatous and vascular processes, which however still require angiography before surgery. CT appearances of important clinical disease patterns were summarized.

Abscess↗
PubMed1981

[Thoracic computer tomography in malignant Hodgkin lymphoma].

A retrospective study of 65 histologically proven lymphoma patients evaluated the staging capabilities of CT in Hodgkin's disease. Nodal and extranodal tumor manifestations were detected in the mediastinum (89%), thoracic bones (23%), pleura (26%), periphery of the lung, and in 14% as an infiltrating thoracic well lesion. Advantages and disadvantages of the method are discussed.

Adolescent↗
PubMed1980

[The diagnostic use of computed tomography in the management of mediastinal abscess (author's transl)].

Computed tomography (CT) is of outstanding importance in the current diagnosis of mediastinal pathology. We have recently treated a patient who underwent laryngectomy and then experienced a septic temperature pattern during the postoperative period which was suspect of mediastinal abscess. A mediastinal CT was obtained, and uncovered a lesion in the anterior mediastinum. Although the test was unable to differentiate between an abscess and a degenerating metastasis, the test was instrumental in first revealing the presence of the lesion, localizing it exactly, and enabling an effective surgical approach to be used for exploring the mediastinum. This entailed an anterior mediastinotomy with partial resection of a rib.

Abscess↗
PubMed1979

[Computer tomography and retroperitoneal fibrosis (Ormond's disease) (author's transl)].

Four patients with retroperitoneal fibrosis (Ormond's disease) were examined by computer tomography; the appearances are described and the differential diagnosis discussed. Computer tomography clearly defines the proliferative-inflammatory process and together with conventional radiology, angiography and lymphangiography it permits a presumptive diagnosis of retroperitoneal fibrosis. The non-invasive nature of computer tomography makes it the method of choice for follow-up of this disease.

Aged↗
PubMed1979

[CT guided percutaneous needle aspiration biopsy (author's transl)].

Technical aspects of CT guided fine needle biopsy are discussed. Since CT enables the topographic-anatomical localization of even small mass lesions, the success rate of CT guided biopsy may be considerably high. The diagnostic potential of the method for the biopsy of various organs is discussed.

Adenocarcinoma↗
PubMed1978

Effect of pyloroplasty on gastric emptying: long term results as obtained with a labelled test meal 14-43 months after operation.

The mean gastric transit time (t) and the half-time of gastric emptying (t/2) of a labelled test meal have been studied in 18 patients more than 1 year after gastric surgery for peptic ulcer and compared with those in 18 healthy controls. Of the patients, 6 had undergone proximal gastric vagotomy alone (PGV), L had had proximal gastric vagotomy and pyloroplasty (PGVP) and in 6 truncal vagotomy and pyloroplasty (TVP) had been performed. The t and t/2 of patients with PGV alone did not differ significantly from the values of the control group. The t and t/2 in patients after PGVP and TVP, however, were significantly lower than in both controls and patients after PGV alone. There was no statistically significant difference between the groups with PGVP and TVP. The results of this study suggest that the lasting effects of vagotomy operations on gastric emptying are due to the drainage procedure rather than the vagotomy.

Adult↗
PubMed1976

[Clinical evaluation of cardiovascular reactions to renal contrast media using an impedance method (author's transl)].

The hemodynamic changes during intravenous urography were studied in 120 non-selected patients (60 patients with bolus injection, 60 with infusion: 30 of each group with methylglucamine ioxitalamate, while the other 30 with sodium methylglucamine diatrizoate). There was a uniform statistically significant increase in heart rate (p less than 10(-9) as well as in cardiac output (p less than 10(-9)) (measured by means of a non-invasive impedance method). The observed changes were more marked following bolus injection than infusion. With the application of methylglucamine ioxitalamate the increase in heart rate, but not in cardiac output, was significantly less (p less than 0,01) than with that of sodium methylglucamine diatrizoate.

Adolescent↗
PubMedDate not supplied

Proximal coronary artery stenosis: three-dimensional MRI with fat saturation and navigator echo.

The purpose of this study was to compare the diagnostic value of MR angiography (MRA) with conventional contrast angiography in coronary artery disease. Thirty-five patients underwent MRA and coronary angiography within 4 hours. Of these, three patients were investigated twice: once before and once after balloon angioplasty. The pulse sequence was a cardiac-triggered, single-slab, three-dimensional gradient-echo sequence, employing a spin-echo navigator echo measurement to track the variation of the diaphragm during the scan. The following segments of the coronary arteries were included in this prospective study: left main coronary artery, proximal and middle left anterior descending, proximal and middle left circumflex, proximal and middle right coronary artery, and intermediate branch, if present. In total, 176 segments were classified as normal or having a stenosis of less than 50% and as having a stenosis of more than 50%. Five patients were excluded because of lack of cooperation. Over all, 45 of 54 stenoses were detected and interpretable by MRA. Sensitivity, specificity, and positive and negative predictive values of MRA for detecting significant stenoses were 83%, 94%, 87%, and 93%, respectively. MRA identified significant stenoses within the major coronary arteries with a high degree of accuracy. Sensitivity and specificity are higher compared with exercise tests or scintigraphy or top of the precise localization.

Coronary Angiography↗
PubMedDate not supplied

CT-guided biopsy of pelvic masses.

CT-guided fine-needle puncture (FNP) was carried out in 74 patients with pelvic masses and resulted in a correct diagnosis in 36/45 patients (80%) with malignant disease. FNP was true-positive in 66.7% and false-negative in 20%. In benign and inflammatory pelvic space-occupying lesions, FNP confirmed the suspected CT diagnosis in all cases by cytology and bacteriology. CT-guided puncture should always be used complementary to CT when a mass of unclear etiology is present.

Abscess↗
PubMedDate not supplied

Analysis of the density of pleural fluid analogs by computed tomography.

A noninvasive method for differentiating transudative and exudative pleural effusions could make thoracentesis unnecessary in many cases. Since computed tomography (CT) can be used to measure tissue densities, it has a potential use in assessing density of intrathoracic fluid. This study was performed to test this possibility. Plastic syringes containing water, saline, and three saline-albumin solutions with densities up to 1.021 g/cc were scanned individually in air, in a chest phantom, and in a dog thorax during apnea. We found significant positive correlations between specific gravity and CT density; coefficients ranged from 0.85 to 0.99. Regression lines for the different test conditions were not statistically different. However, CT number variability, as indicated by the average standard deviation (SD), did differ for the test conditions: 1) Syringes alone, average SD was 3.8 HU; 2) chest phantom, average SD was 5.5 HU adjacent to rib and 5.8 HU anterior to vertebral column; 3) dog chest average SD was 19.2 HU with heart motion and 9.4 HU without heart motion. These results suggest that heart motion is a major factor in CT number variability in vivo, and that differentiation of transudates from exudates is not possible with current CT methods.

Animals↗