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Biomedical subjects

P Vilkki

Publications and source records attributed to P Vilkki.

8 recordsLinked to original sources

Arthroscopic synovectomy in the treatment of patients with juvenile rheumatoid arthritis.

Since January 1982, operative arthroscopy in the knee joint has been performed by us to 22 patients with juvenile rheumatoid arthritis, by whom synovectomy was considered to be indicated. The age of the patients varied from 5 to 16 years. In general anaesthesia, in the connection of arthroscopy, the abrasion of the hypertrophic synovial membrane was made by Stryker's chondrotome. The surgical debris was evacuated by suction. The mobilisation of the knee joint was started 2 days after the operation, and most of the patients walked on the fifth postoperative day. The arthroscopic synovectomy is considered to be a safe operation and, in our opinion, a good alternative method for synovectomy. Rehabilitation time is decisively shorter and, if necessary, operative arthroscopy can easily be repeated, without disturbing scars.

Adolescent

Malignant histiocytosis. Histiocytic medullary reticulosis.

Three cases of malignant histiocytosis occurring in children aged 2 months, 10 months and 14 years, are described. In all children the diagnosis was based on anaemia, granulocytopenia or thrombocytopenia, splenomegaly and marked erythrophagocytosis by bone marrow and lymph node atypical histiocytes. Two children aged 10 months and 14 years, underwent splenectomy after which combined chemotherapy with cyclophosphamide, vincristine and prednisone (COP) was started. In the older child a complete remission was achieved. The younger child died soon after the onset of the treatment. The youngest child was treated with bleomycin, adriamycin, cyclophosphamide, vincristine and prednisone (BACOP). He died of pneumonia and sepsis two months after the start of the treatment.

Adolescent

Preventive treatment of congenital pseudarthrosis of tibia.

If an osteotomy is carried out in a child with congenital angulation of the tibia with segmental sclerosis, a pseudarthrosis develops in many cases. This should be prevented by a bone-graft operation along the concave side of the tibia. The results described illustrate this contention.

Bone Transplantation