[Experimental removal, reimplantation of a lung and contralateral pneumonectomy with survival].
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Biomedical subjects
Publications and source records attributed to P Vanderhoeft.
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A study to evaluate both the pre- en postoperative functional and morphologic status of major anterior chest wall deformities. Four of the eight patients suffered from a progressive reduction in physical capabilities. Preoperative pulmonary function tests demonstrated restriction in pulmonary function. In the postoperative period there was progressive return to normal physical strength without objective improvement in pulmonary function. Pre- and postoperative thoracometric study by CT scan allowed us to evaluate the morphologic changes. Two patients with pectus excavatum (funnel chest) demonstrated not only a right-left asymmetry but also A-P compression of the heart without displacement to the left. We consider this to be one of the causes of functional impairment and an absolute indication for corrective surgery.
Our study groups 7 patients undergoing chest wall resection and 12 patients submitted to en bloc lung and chest wall resection. In the first group, 48 +/- 15 years old, there were 3 females (Darier-Ferrand fibrosis, chondroma, cutaneous gland epithelioma) and 5 males (3 sarcomas, 1 metastasis and 1 osteofibroma). An average of 2 ribs were resected with muscles, pleura and in 3 cases the skin, amounting to between 300 and 1,000 g. Reconstruction was performed : 1 degrees by musculocutaneous flap in 4 cases with 1 fistula; 2 degrees Marlex Mesh in 2 cases with 1 infection; 3 degrees fascia lata in the largest resection that necessitated tracheostomy and prolonged ventilation. There was no death. In the second group, 61 +/- 14 years old, all males, there were 9 bronchial carcinomas and 3 sarcomas. An average 2.5 ribs were resected en bloc with 6 lungs and 6 lobes. The defect was treated : 1. by Marlex Mesh in 3 cases without complications, 2 had tracheostomy and 2 days ventilation; 2. by muscle flap in 9 cases with 3 tracheostomies and ventilation up to 1 month : there were 3 empyemas and 2 atelectasiae. One patient died after a second operation for bronchial stump necrosis. On the whole there is no need for Marlex Mesh.
In our series of 23 patients, operated 27 times, for a iatrogenic stenosis of the trachea, there were 4 deaths by hemorrhage of the innominate artery. Three resulted from shearing of the artery by the tracheal sutures. One came from erosion by a tracheostomy cannula. This fatal complication should be prevented by preserving healthy tissues between the artery and the trachea.
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45 patients admitted in the thoracic non-cardiac surgery service of the U.L.B. between 1966 and 1983 (17 yrs) were short- or longterm survivors of cardiopulmonary resuscitation. In november 1979 the traditional system was supplanted by a mobile unit with reduction of the interval between cardiopulmonary arrest and resuscitation to 1 minute. The obtained results are as follows: A mobile thoracic wall or intra-thoracic visceral lesions or displacement of thoracic content secondary to a recent thoracic intervention or serious injury do not constitute a contra-indication. Closed chest massage was mainly applied. Displacement of the heart secondary to chronic tuberculosis or pneumonectomy or serious thoracic injury are not formal contra-indications. Open cardiac massage was applied during surgical interventions or with hypovolemic shock secondary to massive intra-thoracic hemorrhage or cardiac tamponade. Pulmonary resuscitation with extra-corporeal circulation was only applied when mechanical ventilation did not suffice. All patients succumbed due to an associated lung involvement with destruction of the pulmonary parenchyma. The use of a mobile unit increased the number of successful resuscitations but did not change at all the duration of survival of the patients nor the number of neurological deficits. The survival time was only affected by 2 factors; the primary disease for which the patient was hospitalized and the presumed cause of arrest. All the other factors had no influence on the duration of survival; a. type of intervention; b. place of C.P. arrest and c. method of resuscitation.
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