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Biomedical subjects

P V Rana

Publications and source records attributed to P V Rana.

17 recordsLinked to original sources
PubMed1986

Neurological complications following acute viral conjunctivitis: a new profile.

A study of eleven patients presenting with neurological complications following acute viral conjunctivitis, mostly haemorrhagic, is reported and the literature reviewed. A Guillain-Barre syndrome-like profile was seen in six patients while the remaining had features of radiculomyelitis. Besides asymmetrical neurological deficits, protein cell reaction and residual muscle wasting, the occurrence of dysautonomias was the striking feature noted in the patients with a Guillain-Barre syndrome-like profile. The dysautonomic features included fatal paroxysmal hypertensive and hypotensive crises in one patient and self limiting tachycardias, episodic profuse sweating, abnormal expiration-inspiration ratio and valsalva ratio in four patients. High antibody titers to EV-70 virus were seen in five patients. A follow up of one and a half year revealed poor neurologic recovery in patients with radiculomyelitis as compared to good functional recovery in others. The importance of early recognition and appropriate treatment of dysautonomias is emphasised. The probable aetiopathogenesis of the neurological complications including dysautonomias is discussed.

Adolescent↗
PubMed1985

The Marin-Amat syndrome: an unusual facial synkinesia.

Three cases of facial nerve palsy with abnormal synkinetic movement manifesting with eye closure on jaw opening (Marin-Amat Syndrome) are described. The eye closure occurred only with wide jaw opening and it is felt that the disorder represents aberrant regeneration within the facial nerve with proprioceptive impulses associated with muscle stretch acting as the trigger. Though the movement is the exact opposite of what happens in the Marcus-Gunn phenomenon it is suggested that the term inverse Marcus-Gunn phenomenon be reserved for a congenital lesion with a different pathogenesis.

Adult↗
PubMed1981

Wasted leg syndrome: a clinical, electrophysiological and histopathological study.

Forty cases of 'wasted leg syndrome' were studied clinically and electrophysiologically. Muscle biopsy was examined in nine cases, majority of patients were adults engaged in heavy manual work. The illness was noticed incidently with a strictly unilateral wasting of the whole lower limb (in 65% of cases), of all muscles below the knee (in 22.5% of cases) or of quadriceps muscles only (in 12.5% of cases). The nerve conduction studies and the electromyographic pattern suggested anterior horn cell disorder. Neurogenic atrophy was seen in 7 out of 9 muscle biopsies. A follow up in 12 patients (2-6 years) revealed no progression of the disease. It is suggested that possibly these cases represent an entity, clinically different from other anterior horn cell disorders.

Adult↗