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Biomedical subjects

P V McClintock

Publications and source records attributed to P V McClintock.

5 recordsLinked to original sources
PubMed2001

Phase synchronization between several interacting processes from univariate data.

A novel approach is suggested for detecting the presence or absence of synchronization between two or three interacting processes with different time scales in univariate data. It is based on an angle-of-return-time map. A model is derived to describe analytically the behavior of angles for a periodic oscillator under weak periodic and quasiperiodic forcing. An explicit connection is demonstrated between the return angle and the phase of the external periodic forcing. The technique is tested on simulated nonstationary data and applied to human heart rate variability data.

Journal Article↗
PubMed2001

Modelling couplings among the oscillators of the cardiovascular system.

A mathematical model of the cardiovascular system is simulated numerically. The basic unit in the model is an oscillator that possesses a structural stability and robustness motivated by physiological understanding and by the analysis of measured time series. Oscillators with linear couplings are found to reproduce the main characteristic features of the experimentally obtained spectra. To explain the variability of cardiac and respiratory frequencies, however, it is essential to take into account the rest of the system, i.e. to consider the effect of noise. It is found that the addition of noise also results in epochs of synchronization, as observed experimentally. Preliminary analysis suggests that there is a mixture of linear and parametric couplings, but that the linear coupling seems to dominate.

Artifacts↗
PubMed2001

Modelling the dynamics of angles of human R-R intervals.

Heart rate variability (HRV) data from young healthy humans is expanded into two components, namely, the angles and radii of a map of R-R intervals. It is shown that. for most subjects at rest breathing spontaneously, the map of successive angles reveals a highly deterministic structure after the frequency range below approximately 0.05 Hz has been filtered out. However, no obvious low-dimensional structure is found in the map of successive radii. A recently proposed model describing the map of angles for a periodic self-oscillator under external periodic and quasiperiodic forcing is successfully applied to model the dynamics of such angles.

Electrocardiography↗
PubMed2000

Reversible transitions between synchronization states of the cardiorespiratory system.

Phase synchronization between cardiac and respiratory oscillations is investigated during anesthesia in rats. Synchrograms and time evolution of synchronization indices are used to show that the system passes reversibly through a sequence of different phase-synchronized states as the anesthesia level changes, indicating that it can undergo phase transitionlike phenomena. It appears that the synchronization state may be used to characterize the depth of anesthesia.

Anesthesia↗