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Biomedical subjects

P V Lundt

Publications and source records attributed to P V Lundt.

8 recordsLinked to original sources
PubMed1979

[The effect of betadrenol on examination anxiety (author's transl)].

The effect of betadrenol on examination anxiety was tested in a double-blind study simulating "examination situations". The sample consisted of 60 normal students. After a test examination without prior treatment, each subject was given a single dose of either 40 or 100 mg betadrenol, or a benzodiazepine derivative at the recommended dosage, or a placebo. The test was repeated one hour later. Heart rate, blood pressure and skin resistance were measured continually throughout the progressively complicated psychological test. The increase in the heart rate was significantly lower in the betadrenol-treated subjects than in those given benzodiazepine or a placebo. The behaviour of the blood pressure was similar. Significant improvements in subjective condition and skin resistance in response to betadrenol were contrasted with deterioration after benzodiazepine, and no change after placebos. Improvement in mental alertness in the betadrenol group differed significantly from that in the benzodiazepine group, and there was also an improving trend in reactions. This shows that betadrenol can subdue examination anxiety. Betadrenol was far more effective than a benzodiazepine derivative in all the parameters tested, including psychophysical performance relating to control of a motor vehicle.

Adrenergic beta-Antagonists↗
PubMed1979

[The effect of a beta-adrenergic blocking agent on driving capability (author's transl)].

The effect of Betadrenol, a beta-adrenergic blocking agent, was studied by means of traffic psychology tests in 29 male patients with cardiovascular disorders. The age range was 29 to 60 years. After a 7-day wash-out period, each subject received either 3 x 100 mg Betadrenol or a placebo daily during three days. Subsequently every patient was given 3 x 100 mg of Betadrenol daily during another ten days. The short-term double-blind study revealed no impairment of driving performance. The results of the open study showed significant improvements, especially in concentration and speed of reaction.

Adrenergic beta-Antagonists↗
PubMed1978

Effects of terfenadine and diphenhydramine alone or in combination with diazepam or alcohol on psychomotor performance and subjective feelings.

The effects of single oral doses of terfenadine, diphenhydramine and placebo, alone or in combination with diazepam or alcohol, on psychomotor performance and subjective feelings were evaluated in a double-blind, crossover study in 20 normal male volunteers. Terfenadine 60, 120 and 240 mg had no effect on psychomotor skills and subjective feelings, whereas diphenhydramine 100 mg slightly impaired certain features of psychomotor performance and severely worsened subjective feelings. Terfenadine 120 mg did not influence the adverse effects of oral diazepam 10 mg or of alcohol 0.75 g/kg on psychomotor performance and subjective feelings. In contrast, diphenhydramine 100 mg significantly enhanced these effects of diazepam and alcohol.

Adult↗
PubMed1970

[Epidemiology].

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Animals↗