[Consequences of ventricular radiographic examination in patients under the age of 40].
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Adolescent↗
Biomedical subjects
P U Becker
Publications and source records attributed to P U Becker.
Immunologic changes in acute canine blastomycosis.
Immunologic evaluations were done on a total of 21 dogs presented with acute blastomycosis. There were significant increases in serum alpha 2-, beta-, and gamma-globulins with decreases in albumin concentration. Serum immunoglobulin G was significantly increased, while immunoglobulin M was decreased. Lymphocyte reactivity was evaluated in 6 dogs with acute blastomycosis. There were significant reductions in lymphocyte reactivity in autologous sera to pokeweed, concanavalin, and phytohemagglutinin stimulation. In addition to decreased reactivity of lymphocytes in dogs with normal lymphocyte counts, 40% of dogs with acute blastomycosis were lymphopenic. Abnormalities in cell-mediated immunity may have a role in the pathogenesis of canine blastomycosis.
Acute Disease↗
Evaluation of the agar-gel immunodiffusion test in the diagnosis of canine blastomycosis.
The agar-gel immunodiffusion test was used to evaluated 35 dogs with histopathologically confirmed blastomycosis and 98 dogs without blastomycosis. The test had a sensitivity of 91% and a specificity of 96%. Thirteen of the dogs treated for blastomycosis were tested at 6 to 33 months after treatment with amphotericin B. Ten of 13 dogs became seronegative and 3, though clinically normal, remained seropositive at 19, 20, and 20 months, respectively, after amphotericin treatment.
Amphotericin B↗
Feline skin lymphoma: characterization of tumor and identification of tumor-stimulating serum factor(s).
A feline leukemia virus-negative skin lymphoma was characterized as a T-lymphocyte neoplasm, using the guinea pig erythrocyte rosetting technique. The lymphoma cells responded well to phytohemagglutinin compared with normal feline lymphocytes which did not respond. Serum factor(s) was found in serum of a cat with lymphoma that was highly stimulating to autologous tumor cells, but not to normal cat lymphocytes.
Animals↗
In vivo and in vitro responses of cats sensitized with viable Mycobacterium bovis (BCG).
Cats were injected subcutaneously with viable Mycobacterium bovis (BCG), and immune responses were evaluated at various times after injection. The BCG injection produced fever, leukocytosis, neutrophilia, and lymphadenopathy of regional lymph nodes. Intradermal tuberculin injection produced responses consistent with delayed type hypersensitivity reaction in the treated cats at postinoculation day 21. Skin responses to tuberculin were not significant at postinoculation day 49. The cellular infiltrate at the tuberculin injection site at 48 hours after injection was an admixture of polymorphonuclear cells and mononuclear cells. The BCG produces strong intradermal skin responses in the cat, but the response was not long-lived as in cattle and guinea pigs. The BCG injection did not produce significant changes in the absolute total lymphocyte and absolute T-lymphocyte numbers in peripheral blood. The percentage of T-lymphocytes was significantly higher in the BCG-treated group. Differences were not observed in lymphocyte blastogenesis with tuberculin and non-specific mitogens between BCG-treated and control cats.
Animals↗