Biomedical subjects

P Traubner

Publications and source records attributed to P Traubner.

11 recordsLinked to original sources

PubMed1995

Effect of collateral flow patterns on outcome of carotid occlusion.

The relationship between anatomical configuration of collateral flow and the outcome of the internal carotid artery (ICA) occlusion was analyzed. Sixty-one patients with occlusion of ICA were studied with transcranial Doppler ultrasonography. The authors monitored blood flow velocities in the middle cerebral artery (MCA) ipsilateral to the ICA occlusion during a series of carotid compressions. Blood flow through three major collateral arteries (anterior and posterior communicating arteries and ophthalmic artery) was determined as a residual flow in MCA after each compression. Twelve subjects had asymptomatic occlusion and 46 had stroke; patients with stroke were divided into mild, moderate, and severe stroke groups. Subjects with asymptomatic occlusion had a higher number of patent collateral vessels than severe stroke patients (p < or = 0.001). The same relationship was found between mild and severe stroke patients (p < or = 0.001) and between moderate and severe stroke (p < or = 0.01). Patients with watershed ischemia had a lower number of patent collateral arteries than patients with thromboembolic ischemia as revealed by CT examination (p < or = 0.02). This study demonstrates the crucial role of collateral flow in the stroke pathogenesis and stroke outcome in subjects with extracranial ICA occlusions.

Adult↗

PubMed1994

Compressions of carotid and vertebral arteries in assessment of intracranial collateral flow: correlation between angiography and transcranial Doppler ultrasonography.

The authors examined 61 subjects with carotid angiography and 50 with vertebral angiography. Angiograms were evaluated for collateral flow through the ophthalmic, anterior communicating, and posterior communicating arteries. The authors evaluated the patency of collateral vessels directly using transcranial Doppler ultrasonography; they made indirect detection after the compression of carotid and vertebral arteries while monitoring flow velocities in the middle cerebral artery. They established criteria for the hemodynamic significance of tested collateral vessels. A combination of carotid compressions and transcranial Doppler ultrasonography detected the patency of the ophthalmic and anterior communicating arteries with a specificity and sensitivity of 1.00. Examination of the posterior communicating artery had a sensitivity of 0.97 and specificity of 0.98. Indirect evaluation of collateral vessels can not only detect their presence but also establish their hemodynamic significance with high accuracy.

Adult↗

PubMed1993

Blood flow velocities in basilar artery during rotation of the head.

The authors measured blood flow velocities with transcranial Doppler ultrasonography in the basilar artery after extreme rotations of the head. Studied subjects were divided in two groups according to the degree of asymmetry of the vertebral artery lumens. Rotation of the head caused significant reduction of the mean flow velocity in the basilar artery in the subjects with asymmetry of the vertebral arteries of more than 75%. The decline occurred only after the rotation ipsilaterally to the hypoplastic vertebral artery. This study confirms the importance of the collateral flow in the compensation of dynamic compression of the vertebral artery.

Adult↗

PubMed1992

Short-term prognosis of stroke due to occlusion of internal carotid artery based on transcranial Doppler ultrasonography.

BACKGROUND AND PURPOSE: The clinical course of stroke due to occlusion of the internal carotid artery is influenced by amount of collateral flow. We measured mean frequency shifts in the middle cerebral artery by transcranial Doppler ultrasonography to determine its prognostic value. METHODS: Patients with proven extracranial occlusion of the internal carotid artery and ipsilateral hemispheral stroke were enrolled in our study. We performed transcranial Doppler ultrasonography on 31 patients within 48 hours after the stroke onset and followed up 25 patients in 28 days. At the same time, neurological examination with quantification of neurological deficit was done. We correlated values of flow frequency shifts on the side of stroke with degree of neurological deficit at the onset and at 28 days as well as the degree of clinical improvement and the value of frequency shifts. RESULTS: We found a negative correlation between blood flow frequency shifts in the middle cerebral artery and degree of neurological deficit at the onset (Spearman rank correlation coefficient, -0.567; p less than 0.001). We also found a positive correlation between the change of the neurological deficit during follow-up and frequency shifts at the onset (Spearman rank coefficient, 0.548; p less than 0.05). CONCLUSIONS: Diminished blood flow velocity (mean frequency shift) in the area of stroke is a negative prognostic factor for the degree of neurological deficit at the onset and a negative prognostic factor for possible improvement. Knowledge of hemodynamic conditions in the stroke area may help to improve therapeutic decisions.

Adult↗

PubMed1989

[Vascular headache: circulatory, hemorrheologic, electrophysiologic and psychological aspects].

The aim of the work was to analyze circulatory, rheological, electrophysiological and psychological characteristics of patients with vascular headache, mostly migraine and vasomotor cephalea. The group was formed by 69 patients, mean age 40.4 +/- 9.0 years. It was revealed that: 1. there were no significant changes in rheological properties of blood in the following six parameters: coagulation, viscosity of plasma and blood, platelzo aggregation, of circulating aggregates, 2. there were no significant changes in rCBF (FF,SF,AF and ISI) parameters in the group of patients with bilateral headache but a rising rCBF in unilateral headache, 3. there was a significant reduction of the "peak frequency" in supratrochlear arteries and a significant increase of the flow rate in the intracerebral arteries (a.cerebralis media, a.cerebralis anterior), 42.4% of the patients displayed abnormal but non-specific EEg changes, 5. there was a significant increase of the amplitude of P1 and N2 waves of visual evoked potentials and a non-significant shortening of the latency of wave N1, 6. significant changes were recorded in some psychological parameters, in particular an increase of the score of depressivity, anxiety and neuroticism.

Adult↗

PubMed1988