Baccalaureate-M.D. programs.
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Education, Medical, Undergraduate↗
Biomedical subjects
P Titus-Dillon
Publications and source records attributed to P Titus-Dillon.
Increased serum calcitonin in pregnancy.
Calcitonin, the hypocalcemic, hypophosphatemic polypeptide hormone of C cell origin, has been reported to be high in pregnant women at delivery. Levels of this hormone were determined by radioimmunoassay in 56 pregnant women in all trimesters and found to be above normal in 72 percent. Values were also increased during the first two days postpartum. Calcitonin levels were not correlated with serum calcium or phosphate, except in the first trimester when levels of this hormone were inversely correlated with serum phosphate. Perhaps the hypercalcitonemia of pregnancy serves to protect the maternal skeleton, while allowing the fetus to accumulate calcium.
Adult↗
Inhibition of receptor-mediated uptake of a lysosomal enzyme into fibroblasts by chloroquine, procaine and ammonia.
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Ammonium Chloride↗
A competitive protein binding radioassay for 17alpha-ethynylestradiol in human plasma.
A competitive protein binding radioassay system using a rabbit uterine cytosol preparation for the measurement of ethynylestradiol [EE2e] in human plasma has been developed. Sephadex LH-20 column chromatography is used for the separation of the estrogens prior to assay. EE2 levels were measured in 23 normotensive subjects on contraceptive pills containing either 50 mug of EE2 or mestranol. The EE2 values ranged from 144 to 248 pg with a mean of 211 pg (S.D. +/- 37.94). The method is sensitive enough to detect 25 pg of EE2 in plasma. The intra- and inter-assay coefficients of variation were 7.54% and 10.75%, respectively. Water blanks and plasma blanks from subjects not on pills gave negligible readings for EE2.
Animals↗