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Biomedical subjects

P Thurn

Publications and source records attributed to P Thurn.

At least 37 records · Page 2Linked to original sources

[ECG-controlled cardio-computer tomography (author's transl)].

During ECG-controlled cardio-computer tomography, only certain defined phases of the cardiac cycle are used for computing the image. Consequently several cycles are necessary in order to obtain the required projection. ECG-controlled cardio-computer tomography produces findings regarding dys- or akinetic portions of the myocardium which are in good agreement with the laevo-cardiogram. The septum, apex and antero-lateral wall are demonstrated most easily, since their movement lies within the appropriate plane. Demonstration of the anterior and posterior walls is more difficult, since their movement is angled to the computer tomographic plane.

Diastole↗

[Computer tomography in emergency diagnosis (author's transl)].

The results of 150 examinations by computed tomography in emergency situations are described (about 5% of all CT examinations). There were 80 examinations of the skull, 65 of the abdomen and five of the mediastinum. The results are shown in two tables and include the diagnosis of bleeding, infarcts and inflammatory lesions (abscesses, encephalitis, acute pancreatitis). The morphologic and densitometric findings are compared with the literature and with other imaging procedures. Computer tomography has assumed the most important place in the emergency diagnosis of the skull; as regards the abdomen, it reaches its limitations in the presence of acute vascular occlusion and diseases of the gastro-intestinal tract. In this situation other procedures (contrast studies, angiography) and endoscopy are to be preferred since these demonstrate the tubular organs longitudinally, unlike the transverse image produced by the CT scan. Acute diseases of the lungs can be demonstrated more quickly and simply by conventional radiography. CT is a non-invasive and rapid procedure, which can demonstrate haemorrhages, abscesses and exudates in the mediastinum and abdomen directly and also show their topography. The method is therefore essential for emergency diagnosis of conditions involving the trunk.

Adolescent↗

[Computer tomographic and angiographic studies of histologically confirmed intrahepatic masses (author's transl)].

The computer tomographic and angiographic findings in 53 patients with intrahepatic masses were compared. The histological findings show that 17 were due to echinococcus, 12 were due to hepatic carcinoma, ten were metastases, five patients had focal nodular hyperplasia, three an alveolar echinococcus and there were three cases with an haemangioma of the liver and a further three liver abscesses. Computer tomography proved superior in peripherally situated lesions, and in those in the left lobe of the liver. Arteriography was better at demonstrating lesions below 2 cm in size, particularly vascular tumours. As a pre-operative measure, angiography is to be preferred since it is able to demonstrate anatomic anomalies and variations in the blood supply, as well as invasion of the portal vein or of the inferior vena cava.

Angiography↗

[Computer tomography of aorto-coronary bypass (author's transl)].

Computer tomography is a non-invasive method for demonstrating occlusion or patency of an aorto-coronary bypass. The early results of computer tomographic investigations of 77 bypasses in 51 patients are described. CT diagnosis of bypass patency is well established, but further work will be required to determine the accuracy of computer tomographic diagnosis of bypass occlusion.

Arterial Occlusive Diseases↗

[Complications of selective retrograde laevocardiography. A survey of 2000 examinations (author's transl)].

The incidence of complications in 2000 selective retrograde laevocardiograms is reported. Seventy-four complications were observed in 69 patients. None of these was fatal. On 39 occasions cardiac, and on three occasions cerebral complications were observed. In 20 patients there were complications at the site of puncture and in four patients sepsis or bacteraemia. Contrast sensitivity or allergy was found in eight patients. The relationship, described in the literature, between intramural contrast deposition and the type of catheter, ventricular size and ventricular wall was confirmed by our own observations, as well as the most frequent situation on the posterior wall of the left ventricle.

Adult↗

[CT and the heart: present state of the art and its future. A review (author's transl)].

Overview of non-invasive cardiac computed tomography (CCT) presently technologically feasible--with an outlook on the future. CCT seems to be an addition to the cardiodiagnostic imaging spectrum of cardiac isotope scanning and cardiosonography already firmly established; and it will probably soon have to establish its rank. The indications for CCT already proven and those awaited in the future will be systematically analyzed in this presentation. Conventional present-day CCT with long scanning times of 3-5 seconds has already provided satisfactory clinical information, considering the fact that there is slow motion of the damaged area in myocardial disease as experimentally shown by an over 20 min long arrest of contrast-material (given i.v.) in the infarcted areas. EKG-gated scanning and reconstruction techniques under development will provide better spatial and chronological resolution. However, much development is yet to be done, it is to be expected that CCT will eventually render data about the function of a specific area of the ventricular wall. Decreased scanning times and scanning intervals will provide dynamic studies of cardiac function and allow time/concentration examinations. These latter studies will be especially valuable to demonstrate the intracavitary cardiac flow in detail.

Cardiomegaly↗

[Mulitple primary carcinomas.--Analysis and discussion of 74 cases (author's transl)].

This study is based on the examination of 3132 patients. 74 of these patients (2,6%) had clearly demonstrated multiple tumors. Most of them were located in the mamma, the female sex organs, the oral cavity and the pharynx as well as in the lymphatic and hematopoietic organs. A significantly greater risk to develop secondary carcinomas was found in patients suffering from primary mamma carcinomas. A correlation with other tumors of the female sex organs can also be supposed. In case of other malignant tumors, it was not possible to demonstrate any tendency to form secondary carcinomas. Important informations about pathogenesis and etiology of carcinomas can be obtained by the performance of detailed examinations which have to be based on reliable statistical methods.

Breast Neoplasms↗

[Coronary calcification and luminal diameter in coronary disease (author's transl)].

Two hundred and thirty-six patients with coronary heart disease were examined by coronary angiography and laevo-cardiography. In 111 patients (47%) there was coronary artery calcification. Of these, 108 patients (97%) showed abnormal findings on the coronary angiogram; in 72 patients (67%) coronary stenosis was greater than or equal to 50% of the lumen. The severity of the stenoses increased with the amount of calcification. There were only three false positive findings and the presence of coronary calcification indicates coronary sclerosis with a high degree of probability. Fluoroscopy is the simplest and most sensitive method of examination and is of great value in the non-invasive investigation of coronary sclerosis.

Calcinosis↗

[Computer tomography in the diagnosis of aortic aneurysms (author's transl)].

The paper describes the diagnosis of ten thoracic, 20 abdominal and three peripheral arterial aneurysms by computer tomography. This permits a definite diagnosis by a non-invasive method, it defines the extent of the aneurysm and the amount of thrombus in the aneurysm; it permits recognition of a leak and is painless and without risk and can be performed rapidly. Morever, computer tomography provides an accurate control of growth of the aneurysm. In some cases a dissection can be recognised. The use of adequate quantities of intravenous contrast medium prevents any possibility of an incorrect diagnosis. The extent and density of the aneurysms, their lumina, clot and wall thickness, as determined by computer tomography are described. The values are compared with the aortic diameters of patients with normal vessels. The advantages of the method, compared with other procedures, are discussed and its role in the diagnosis of aortic and peripheral arterial aneurysms is described.

Aged↗

[Image characteristics of the computer tomograph (author's transl)].

In the present paper the images produced by spheres of varying diameter (d = 4,6,8,10 mm) embedded in a homogeneous substance of varying densities (H' = 3,48,93,137 Hounsfield units) as produced by computer tomography were studied. Measurements show that for each sphere diameter there is a minimum contrast between the substance of the sphere and its surroundings which must exist in order to show this sphere by computer tomography. It was also shown that the partial volume effect is of significance for the attenuation of the spheres. The effect of the position of the spheres within the slices to be imaged was studied. The results clearly indicate that in the investigation of small tissue changes in the body, the thickness of the slice and patient displacement should be kept as small as possible.

Absorptiometry, Photon↗

[Computer-cardio-tomography in idiopathic hypertrophic subvalvular aortic stenosis--a new contribution to non-invasive diagnosis (author's transl)].

The use of computer tomography as a non-invasive procedure in the diagnosis of idiopathic hypertrophic subvalvular aortic stenosis is described. Seven patients were investigated in whom the diagnosis had been confirmed by echocardiography and laevocardiography with pressure measurements. Details of the method are discussed and computer tomography and echocardiography are compared. The features of greatest differential diagnostic importance relating to asymmetrical septum hypertrophy are discussed.

Cardiomegaly↗

[Image properties of computer tomography. III. Measurements on homogenous materials. Relationship of attenuation and scatter to various parameters (author's transl)].

The present paper investigates the variations due to various parameters on the image of homogeneous materials as obtained with the Somatom CT scanner. Sugar solutions were used with concentrations equivalent to the absorption values of soft tissues. Because of quantum noise, attentuation at various points is not uniform, but is distributed in a Gaussian manner round a mean value. Using the Evaluskop it was possible to determine the degree of scatter. It was shown that, with increasing density of the material, the scatter increased and that this can be reduced by subjecting the tomogram to a smoothing process. It was further shown how the scatter depends on various parameters, such as thickness and dose. The amount of scatter in a tomogram is important in determining the density gradation which can be a achieved.

Absorptiometry, Photon↗

[Computer tomographic diagnosis of pericardial effusions (author's transl)].

Thirty patients with suspected pericardial effusions, or with cardiac enlargement of unknown cause were examined by computer tomography. In 19 cases a diagnosis of pericardial effusion or haematoma was made. All these cases were confirmed by echo cardiography or transthoracic puncture. The accuracy of computer tomography diagnosis did not depend on the aetiology, but could be increased by contrast enhancement. The computer tomographic criteria are enumerated and compared with those of echo cardiography. Examples of the most important differential diagnoses are discussed.

Adult↗

[A comparison of computer tomography and ultrasound for the demonstration of vessels in the abdomen and retroperitoneal space (author's transl)].

The value of computer tomography and ultrasound for demonstrating vessels in the abdomen and retroperitoneal space was compared. The methods were equal in their ability to demonstrate the major vessels situated centrally, but computer tomography proved better at differentiating arteries and veins situated peripherally. On the other hand, sonography proved a simple means of differentiating intrahepatic vascular structures.

Abdomen↗

[Computer-Cardiotomography (author's transl)].

Based on our first 200 investigations computed tomography of the heart is demonstrated as a new non-invasive roentgenography on typical examples and compared with the findings of the conventional roentgenogram. With the present technology the following indications for computed tomography of the heart seem to be reasonable: Calculation of size and volume of the cavities of the heart; intracavitary space occupying lesions (tumor, thrombus): demonstration of the thickness of the ventricular wall and ventricular septum and their changes caused by hypertrophy, myocardial infarction or septal defect; demonstration of aortic and ventricular aneurysm; demonstration of pericardial effusion, pericardial tumor, pericardial cyst of lipoma.

Cardiomegaly↗

[Extension of thoracic roentgen diagnosis by computer tomography (author's transl)].

In 400 examinations of the thorax results of computer tomography were compared with respective pa chest films and conbentional tomograms. In the peripheral areas of the lung, interstitial parenchymal alterations and metastases were better visualized by CT. The size of central bronchial carcinomas and space-occupying lesions of the thoracic wall can be determined with greater accuracy by CT. Primary tumors, lymphnode enlargement and vascular alterations can be differentiated and localized more precisely by CT. The size of the heart chambers, intracavitary tumors as well as septal and myocardial wall thickness can be determined non invasively.

Aortic Aneurysm↗

[Mitral stenosis on conventional radiographs. II. The relationship between pulmonary venous and arterial hypertension, their haemodynamic parameters and calcified mitral valves (author's transl)].

In the second paper, the relationship between pulmonary venous and arterial hypertension and calcification in the mitral valve is analysed statistically and its patho-physiological significance discussed. In one hundred cases of mitral stenosis the left atrium, as seen on the lateral projection, was always enlarged, but its size was independant of atrial pressure or the pressure gradient across the mitral valve. Apart from pulmonary fibrosis and haemosiderosis, the abnormal findings increased with increasing mean atrial pressure. Pulmonary-arterial mean pressure of more than 30 mmHg was found particularly in the presence of mitral valve calcification (94%). Calcification of the valve is the most important and reliable indicator for evaluating the severity of the stenosis.

Adult↗