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P Testas

Publications and source records attributed to P Testas.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Mechanical circular colorectal anastomosis using a transanal approach. Apropos of a series of 51 cases].

Automatic circular suture forceps offer new technical possibilities for the confection of colorectal anastomosis. A retrospective study was conducted in 51 patients, representing a homogeneous group of anastomoses performed by the same surgeon using the same operative technique and with routine review by barium enema examination on the 8 th postoperative day. Technical difficulties during operation were encountered in 10 patients (19.6%) requiring supplementary sutures in 3 cases and protective colostomies in 3 others. Review examinations revealed anastomotic dehiscence in 7 cases (13.7%), only 3 (5.9%) of these radiologic fistulae provoking clinical manifestations, and only one of these (1.9%) necessitating recovery operation. Perfect compliance with conditions of use of the mechanical forceps and a minute technique identical to those of manual sutures produced excellent early result with circular mechanical suturing using EEA forceps when compared with manual suturing methods. This was particularly true in Goligher's series in which there were 51% of radiologic fistulae. Under certain difficult conditions, the use of EEA forceps simplifies performance of a colorectal anastomosis, mechanical anastomosis using the circular forceps constituting an undeniable technical progress in colorectal surgery with conservation of anal sphincter.

Adolescent↗
PubMed1982

[Experimental pancreatitis of ductal origin. Anatomo-pathologic and ultrastructural study].

The injection of bile under low pressure led in 21 dogs out of 30 to a process of acute pancreatitis and to the reproduction of the different histopathological types of pancreatitis seen in man. This represents a weighty argument in favour of the concept of oedematous pancreatitis, interstitial pancreatitis with sometimes major cytosteatonecrosis and necrosing pancreatitis as different manifestations of the same disease, which is not universally accepted. Our research has once again emphasized the fact that the interstitial phenomena and in particular fatty necrosis precede parenchymatous necrosis. Morphological studies were used to attempt to define the link between fat necrosis and acinar necrosis. Light microscopy showed that there was no topographic evidence of direct involvement of the acinar cell in contact with fat necrosis. By contrast, ultrastructural studies revealed initial involvement of the basal pole of the acinar cell. This would emphasize the responsibility of interstitial phenomena in the maintenance, if not the induction, of acinar necrosis. It cannot be excluded that fat necrosis could indirectly, via the liberation of factors carried by oedema, play a role in these phenomena of acinar necrosis. In addition, it was noted that the apical poles of the acinar cells did not seem to be damaged, the acinar lumina were dilated and there was loss of the intercellular junctions. This would hence indicate the possible passage into the interstitium of a toxic substance (bile salts, enzymes liberated in excess) coming directly from the acinar lumina.

Acute Disease↗
PubMed1981

[Cytosteatonecrosis: cause or consequence of acinic necrosis in acute pancreatitis? (author's transl)].

It is now common knowledge that per-operative findings and pathological examination results may be discordant in acute pancreatitis. A study of 25 cases considered as "necrotizing" and subjected to histological examination has prompted the authors to devise a new experimental model of acute pancreatitis in dogs, using Wirsung's canal. They found that steatonecrosis precedes acinic lesions and hypothesize that it might be responsible for necrosis of the glandular tissue.

Acute Disease↗
PubMed1981

[Dimethylnitrosamine hepatic cirrhosis in the rat (author's transl)].

Chronic intoxication with dimethylnitrosamine (D.M.N.A.) in the rat induced an experimental cirrhosis which seems stable in time. The intoxication was done by forcible feeding either with 7 or 8 mg/kg of D.M.N.A., three consecutive days a week, for 9 weeks. Chronical intoxication resulted in 50% of hepatic cirrhosis in the 7 mg/kg group and 63% in the 8 mg/kg group. --The diagnostic of hepatic cirrhosis was done by pathological study on the left lobe. --In all cirrhotic rats, verified by histology, biological test were disturbed in a significant way, compared to untreated rats, but not to non cirrhotic intoxicated rats. There was no correlation between pathological anatomy and biology. --Cirrhosis persists after the intoxication but survival duration is much shorter in the group intoxicated with 8 mg/kg of D.M.N.A. --There was no difference in the constitution of cirrhosis between Wistar and Sprague Dawley strains. Therefore the best procedure to induce cirrhosis in rats is chronical intoxication by administration of 7 mg/kg of D.M.N.A. during 3 consecutive days a week for 9 weeks. Pathological study are the only reliable tests to determine the constitution of cirrhosis.

Animals↗
PubMed1980

[Menetrier's disease and gastric tumors (author's transl)].

The authors describe three patients with Menetrier's disease and cancer of the stomach. Menetrier's disease may be a precancerous condition of the association may be a coincidence, but it would still seem preferable to propose surgical treatment and "rather a total gastrectomy". Detecting early signs of cancer on fibroscopy is difficult in this disease because of the characteristic large hypertrophied mucosal folds.

Adenocarcinoma↗