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Biomedical subjects

P Teniere

Publications and source records attributed to P Teniere.

At least 19 recordsLinked to original sources

Detection of ploidy in colorectal tumors. A comparison between flow cytometry and cytogenetics.

Parallel investigations of ploidy by flow cytometry and cytogenetics were performed in 20 colorectal tumors. Flow cytometry detected an aneuploidy in 13 tumors with DNA indices ranging from 1.13 to 2.21. The other samples exhibited an apparent diploid DNA content. Cytogenetic analyses revealed an abnormal chromosome count in 14 cases and a frequent implication of numerical or structural changes in chromosomes 1, 7, 12, 17, 18, and 20. DNA content evaluated by both techniques was generally concordant with minor discrepancies not exceeding 10%. In six cases, cytogenetics failed to find the cell populations detected by flow cytometry. These results indicate that flow cytometry and cytogenetics are reliable and complementary techniques, particularly in near-diploid tumors, where flow cytometry has some difficulties in detecting variations from diploidy below to 8%.

Adenocarcinoma

[Evaluation and utilization patterns of antibiotic therapy. A study in 4 hospital departments].

The use of antibiotics in 480 cases in 4 hospital wards during 1988 was assessed by examination of medical records. Only the first antibiotic therapy administered during the first stay in the ward for each patient was included. Antibiotics were administered to 163 in-patients (37% of hospitalizations) for infections in 113 (26%) cases. Amoxycillin and macrolides were the drugs most frequently used. Sixty-eight percent of the treatments were administered in the absence of microbiological data. Single drug therapy was used in 60% of treatments. Fifty in-patients (11% overall; 41% of patients undergoing surgery) received antibiotics for prophylaxis. The exact indication(s) for the choice of therapy was not given in the medical records of 39% of cases. Treatment started within 48 hours of infection in 15% of the cases. Overall, 93% of the treatments given were indicated, but 53% were inappropriate because they were too expensive, unlikely to be effective or were multiple drug therapy without justification. There are a variety of factors that cause such inappropriate administration of antibiotics.

Adult

[Bladder incarceration in a Spigelian hernia].

A patient presented with bladder in an incarcerated Spigelian hernia. Diagnosis was made by clinical examination and ultrasound imaging. Surgical treatment ensured good parietal refection. Such a case has not been previously reported in the literature.

Aged

[Role of duodenal diversion in the treatment of gastro-esophageal reflux].

Total duodenal diversion (TDD) is an original and efficient form of surgical treatment for gastroesophageal reflux. This technique was performed in 11 patients for severe esophagitis by first intention or after previous surgery. Results were excellent on reflux but 3 patients developed functional complications of the operation. This morbidity must lead to restrain the indications of the TDD.

Adult

[Carney's triad: a new case associated with adrenal cortex adenoma].

Carney's triad is a combination of at least 2 of 3 tumor sites: multiple gastric leiomyoblastoma, pulmonary chondroma and paraganglioma, most often extra-adrenal and secreting. Thirty-three cases have been published; we report a new case in a 20 year-old woman, with multiple gastric leiomyoblastomas, liver metastasis, and bilateral pulmonary chondroma. The research of paraganglioma, in regard to Carney's disease, led to the discovery of corticoadrenal adenoma.

Adenoma

[Acute intestinal ischemia from arterial thrombosis. Value of emergency arteriography and revascularization].

A 77 year old woman undergoing surgery for acute digestive arterial thrombosis, was successfully revascularized without intestinal resection. Early diagnosis is difficult and is based upon evaluation of past history and an arteriography when there is the slightest doubt. Apart from when necrosis is already developed, revascularization by aorto-superior mesentric by-pass using an autologus saphenous vein and a routine "second look" to assess intestinal viability is the best therapeutic approach.

Aged

[Isolated aneurysm of the common hepatic artery. Apropos of a case report].

A case is reported of an isolated aneurysm of the common hepatic artery revealed by pain in liver region. The etiology is mainly dominated by atheroma and media dysplasia. Detection is currently during investigation of a pain syndrome or jaundice and no longer after rupture of aneurysm. Ultrasound imaging value is emphasized and angiography provides valuable data. Surgical treatment and particularly the indication for hepatic revascularization are discussed as a function of anamnestic and angiographic arguments and intraoperative findings.

Aneurysm

[Treatment by arterial embolization of a case of Wirsung's duct hemorrhage].

A 49 years old patient was hospitalized following a eight days episode of gastro intestinal bleeding. Medical history revealed a chronic pancreatitis for more than three years. Physical examination upon admission was unremarkable. Acute oesophago-gastro-duodenoscopy showed red blood issue from the papilla. Echotomographic examination revealed no pancreatic pseudo cyst. A coeliac angiogram showed an extravasation of contrast material. Subselective pancreatico duodenal angiogram revealed the extravasation and the instantaneous opacification of the pancreatic duct with flow into the duodenum. Arterial embolization was chosen for treatment and stopped the bleeding. The patient has now been followed for three years and has had no recurrence of gastro intestinal bleeding.

Celiac Artery

Diverticulitis in a patient with a 47-year defunctionalized colon.

A patient who had a cecostomy because of a complicated appendicitis at the age of 17 functioned with an excluded colon for 47 years. He was then hospitalized for diverticulitis and left pericolic abscess. After treatment of the abscess by left segmental colectomy and reanastomosis, the cecostomy was closed. Two years later, he presented a normal bowel habit and improvement of his diverticulosis. Rectal manometric study showed that the rectal was normal both before and two years after surgery. Occurrence of diverticular disease in a normally innervated and vascularized, but almost empty, colon presenting with normal mechanical properties is consistent with Burkitt's hypothesis concerning long-term effects of a low residue diet on the gastrointestinal tract.

Colectomy

[Value of per-operative measurement of the blood flow in vascular surgery (author's transl)].

Post-operative thrombosis in vascular surgery results from either technical error of deficient arterial outflow and can be avoided by checking, during the operation, that the new circulatory conditions created are adequate. Among the most frequently used control methods arteriography occupies a prominent place but requires a sophisticated equipment to be truly reliable. Per-operative measurement of the blood flow is much simpler. It objectively assesses the haemodynamic value of the arterial reconstruction and provides useful information on the short-and medium-term patency of the vessels.

Aged

[Infection of vascular sutures: a report on 26 cases (author's transl)].

The authors describe 26 cases of infection after vascular surgery, affecting a Dacron prosthesis in 13 cases and venous grafts in the other 13 patients. The site of infection was usually the region of Scarpa's triangle (15 cases) with the presence of enterobacterium in 40% of cases. The most frequently isolated germ was staphylococcus aureus (20 cases). Infection was revealed by hemorrhage in 17 patients and was evidence of breaking down of the anastomosis. Results of surgical treatment in the two groups were evaluated by using three criteria: --persistence or not of infection, --vital prognosis, --functional prognosis. Surgical treatment methods and possible contamination sources are discussed. When the operative zone is infected, the authors recommend ablation for the prostheses and conservative therapy for venous autografts. The prosthesis was left in place in 5 patients, and only one patient recovered, while two deaths occurred. In the 10 cases where ablation of the prosthesis was performed, however, the infection was cured, and in 4 patients there was revascularization in the infected area. Apart from these cases, conservative therapy was applied in 11 cases and healing occurred in all of them.

Adult

[Colitis marginal to cancer. Apropos of 7 cases].

The authors report 7 new cases of colitis above a carcinoma. The study of these cases and of those reported in the literature shows the main pathological characteristics of the lesions and permits discussion of the pathogenesis. Chronic ischemia caused by an increase in intraluminal pressure above the neoplastic stenosis seems to be the main etiological factor.

Aged