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Biomedical subjects

P Tellier

Publications and source records attributed to P Tellier.

48 records · Page 3Linked to original sources

[Dissecting osteochondritis of the patella. Apropos of 12 cases].

The authors report 12 cases of osteochondritis dissecans of the patella. The relative rarity of this condition (one hundred published cases) is perhaps only apparent, as the diagnosis is sometimes difficult early in the disease. Drawing from their personal cases and from data in the literature, the authors recall the clinical and radiological signs, describe the place of complementary investigations and therapeutic indications and discuss the various pathogenic theories, none of which are fully satisfactory.

Adolescent↗

[Treatment with intracoronary streptokinase in the acute phase of myocardial infarct. Preliminary results apropos of 20 cases].

Twenty patients with primary myocardial infarction (mean age 55 years +/- 6) were treated with intracoronary streptokinase in the acute phase. The mean interval between the onset of chest pain and treatment was 4 hours 30 minutes (extremes, 30 minutes and 6 hours). The total quantity of streptokinase required to obtain coronary revascularisation varied from patient to patient and with the technique used, but it was less than 350,000 units in all cases. The immediate results were favourable in 80 p. 100 of cases with respect to the coronary obstruction, in 50 p. 100 of cases with respect to relief of pain and in 35 p. 100 of cases with respect to ST elevation. It is not possible to confirm the efficacy of this therapy in left ventricular function from the results of this preliminary study. The authors observed, however, that the best results as assessed by 2D echocardiography, left ventricular angiography, and Thallium 201 myocardial scintigraphy were obtained in patients treated early (before the 3rd hour). They emphasise the need to check the level of antistreptokinase antibodies before starting treatment to assess the optimal total dosage for each individual patient, in order to obtain a local effect without disturbing the overall coagulation mechanism.

Adult↗

[A fast transient osmotic method. Simultaneous in vivo determination of the reflexion coefficient and of the permeability/filtration coefficient ratio of the pulmonary capillary endothelium in the dog].

Thermodynamic variables characterizing the transport of water and urea across Dog pulmonary capillary membrane were obtained in vivo by means of a pulse transient osmotic method. Results were inconsistent with the hypothesis of a homoporous membrane. When data were interpreted in terms of an exclusive water channel and of a shared pore pathway, the value of the pore reflexion coefficient was close to zero for urea.

Animals↗

[Arthropneumotomography in recurrent dislocations and subluxations of the shoulder. Methods, results, and indications in 45 cases (author's transl)].

The authors describe the results of arthropneumotomography in 45 patients with recurrent dislocations or subluxations of the shoulder. The method used is given in detail and the need for excellent quality glenoid profile sections, as described by Bernageau, is emphasized. The results are analyzed for bone lesions, capsuloligamentary lesions, and intra-articular foreign bodies. The two latter conditions are specifically demonstrated by arthropneumotomography. These results are then described radiological and surgical correlations, and the indications defined. Arthropneumotomography is therefore of value when a decision is to be taken as to the need for operation.

Adolescent↗

Infinite dilution conductimetry of plasma and urine: correlation with osmolality.

The infinite dilution conductivity (IDC) of plasma and urine allows a measurement of the electrolyte content in small samples (5 to 15 microliter). The method was compared to the corrected osmolality (II'p) measured by the freezing-point depression. A linear correlation existed between II'p and the IDC: for plasma: II'p = 13.10 sigma o,p + 37.00 (n = 46 and r = 0.9949) for urine: II'u = 12.75 sigma o,u + 16.56 (n = 85 and r = 0.9504). The measurement of the IDC does not depend on protein concentration and can be used instead of the osmometer methods to determine the total plasma and urine electrolyte content.

Blood Physiological Phenomena↗

[Deceptive and revealing clinical forms of acute respiratory insufficience in chronic bronchopneumopathies].

The authors report 6 cases of acute respiratory failure complicating chronic bronchial and lung disease admitted to hospital with the diagnosis of: heart disease, 3 cases, pulmonary oedema, pulmonary embolism, atrial flutter; status asthmaticus : one case; neuro-psychiatric disease : 2 cases (toxic coma and agitation). The authors emphasize the frequency of chronic bronchial disease and recall the signs of acute decompensation discussing the possible difficulties in diagnosis and the therapeutic implications.

Aged↗

[Exercise myocardial scintigraphy for the positive and topographic diagnosis of coronary disease. Study in 115 patients without antecedents of myocardial infarction].

In a group of 53 subjects (prevalence of the disease = 91%), the sensitivity of stress myocardial scintigraphy is lower (66%); the predictive value of a negative SMS is only 28 per cent: these results can be explained by the clinical profile of the subjects included in this group (men with an average age of 50 with typical effort angina), but also by the high incidence of one vessel stenoses of the right coronary artery or the circumflex artery (19/35) which are less accessible to SMS. For the series as a whole, the combination of the two tests provided optimal results: double positivity (SMS+/stress ECG+) has a predictive value of 97 per cent; double negativity (SMS-/SE-) corresponds to 83 per cent true negatives. Furthermore, the combination of SMS+/SE+ is suggestive of more severe coronary disease (defined by the presence of a tight stenosis of the IVA or multi-vessel disease). Such severe disease is encountered in less than 7 per cent of cases when the two tests are negative.

Adult↗