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Biomedical subjects

P Teillac

Publications and source records attributed to P Teillac.

140 records · Page 8Linked to original sources

[Indications of the trans-diaphragmatic approach to the supra-celiac aorta].

The trans-diaphragmatic approach of the supra-celiac aorta can be performed in two different ways, according to the indications of this approach: The approach through a restrictive way, by simple dissociation of the muscular fibers of the posterior angle of the oesophagal hiatus allows an high and fast aortic clamping, especially helpful when a serious sub-diaphragmatic bleeding is encountered. It can also be used at the time of reintervention on the sub-renal aorta, in case of juxta-renal aortic thrombosis or in case of abdominal aortic aneurysm involving renal arteries. The approach through an extensive way, by saggital section of the muscular fibers of the posterior angle of the oesophagal hiatus and of the arcate ligament increases considerably the length of the exposed aortic segment and allows the implant of a by-pass graft on the lower thoracic aorta; this graft can be used to revascularize the underlying aortic step; it can also be used to shunt a lesion of the thoracic aorta.

Aorta, Thoracic↗

[Monoclonal anti-prostatic acid phosphatase antibodies (production and characterization)].

5 monoclonal antibodies have been produced by Köhler and Milstein. The production and the characteristics of the monoclonal antibodies are presented. They are all IgG1 and have high specificity against prostatic cells producing prostatic acid phosphatase. These monoclonal antibodies can be used to perform immunoscintigraphies and immunolymphoscintigraphies to titrate prostatic acid phosphatase serum levels and to identify the prostatic origin of a tumor.

Alkaline Phosphatase↗

[Acquired stenosis of the upper urinary tract after percutaneous nephrolithotomy].

The authors present two well documented cases of extensive acquired stenosis of the infra-pelvic upper urinary tract following percutaneous nephrolithotomy. This type of complication appears to be exceptional as, by combining the series of two centres, it represents only two cases out of more than five hundred cases treated. The delay in appearance is of the order of six months. The more or less complex nature of the procedure does not appear to be responsible. It is difficult to determine the exact mechanism fo this complication: several hypotheses are proposed. A few rare cases have been reported in the literature without raising any particular attention. These complications required difficult reconstructive surgery with a good result in both cases. Although these complications seem to be difficult to prevent, they should be systematically detected by ultrasonography at two months and at six months to avoid delay in the diagnosis of functional renal exclusion.

Adult↗

[Vesico-urethral fibroscopy. Reflections after 4 years' practice].

The visualisation of the lower urinary tract by the mean of a fiberscope makes an advance when compared to rigid endoscopy mainly in male patient. Technical features of the fiberscopes suitable for urology thus basic technique of the examination are described. Main advantages are painfree and total visual scanning of the mucosa. Disadvantages are very low.

Cystoscopy↗

[Percutaneous nephrolithotomy: perspectives for the future. Analysis of 250 cases in 3 years' experience].

The authors report their experience of percutaneous nephrolithotomy over a period of three years. The analysis of the first 250 cases performed reveals a low morbidity, with serious complications in 1% of cases, and an acceptable complete success rate of 83%. The indications for percutaneous nephrolithotomy have been modified since the opening of an extracorporeal lithotripsy unit. The choice between the two techniques depends on their efficacy and their expected morbidity based on four criteria: the volume, chemical composition and site of the stone and the morphology of the upper urinary tract. Percutaneous nephrolithotomy is the treatment of choice for large stones (greater than 2.5 cm), hard stones or those formed proximally to a stenotic lesion of the urinary tract, which can then be dilated at the same procedure. A combination of the two methods is sometimes uses to treat staghorn calculi with a success rate of 80%. On the other hand, very large staghorn calculi with caliceal branches are best treated by open surgery.

Adolescent↗

[Reabsorption of the irrigation solute during percutaneous nephrolithotomy].

The publication of several accidents, possibly due to the reabsorption of irrigation solutions in the course of percutaneous nephrolithotomy, prompted the authors to quantify the amounts of glycine (1.50 per cent glycocol) reabsorbed in these operations, and to determine the metabolic consequences. In a prospective study of twelve patients subjected to fourteen percutaneous nephrolithotomies, the hemodilution parameters (natremia, protidemia, hematocrit and osmolality) and the amino acid content of the plasma were measured preoperatively, at operation, and immediately postoperatively. The study indicates that there is a hemodilution and reabsorption of irrigation solute comparable to that observed in transurethral resections of the prostate. The resultant hyperglycinemia probably explains the significant increase in ammonemia noted in all the patients. One theory is that hepatocellular insufficiency may increase this ammonemia. This might suggest the advisability of using saline solution, at least in these patients (that is, of course, in the absence of electrical lithotrity).

Adult↗

[Percutaneous renal surgery. Analysis of 100 cases of percutaneous nephrolithotomy].

The authors review a series of 100 consecutive patients treated by elective percutaneous nephrolithotomy. The success rate was 83%, and the complication rate, under 2%. For these reasons, percutaneous nephrolithotomy is becoming an established procedure for the surgical management of kidney stones. After an initial phase, the one-stage manipulation was performed with a mean hospital stay of 4 days in 70% of cases.

Adult↗

[Benign prostatic hyperplasia: patients' perception of medical treatment and their expectations. Results of a french survey involving patients treated with finasteride].

Benign prostatic hyperplasia (BPH) is increasingly common in medical practice, as a result of the inevitable aging of the population. The current therapeutic strategy includes three alternatives: watchful waiting, medical treatment and invasive therapy. Finasteride is one of the pharmacological options available. Many clinical studies have demonstrated its efficacy and good safety profile in patients with BPH. The survey we report provides new insights into what has to date been a purely therapeutic approach by taking into consideration patients' expectations and their perception of finasteride treatment. Results indicate that the main preoccupation for patients with BPH is that the pharmacological treatment will reduce the risk of major urological complications and the need for surgery (treatment characteristics considered as very or extremely important by 88 and 93% of patients, respectively). Decreasing symptoms and improving quality of life take second place after these primary concerns. Patient perception of finasteride is excellent. Nearly all patients are satisfied by the efficacy of the treatment, 89% of them reporting good to extremely good improvement of symptoms, the rapid onset of relief being particularly important. The efficacy of finasteride is not hindered by any tolerability issues and is further strengthened by its ease of use. Although this novel survey includes a number of biases, it nevertheless demonstrates that treatment of BPH with finasteride is well accepted by patients and satisfies their expectations. In addition, it provides a mass of general epidemiological data on patients with BPH, as well as on current medical practice regarding this condition.

Aged↗

[Developmental aspect of renal suppurations. Apropos of 2 cases].

The authors set out to differentiate between two types of renal parenchymal suppuration in the light of two personal cases treated recently - renal abscess and localized acute bacterial nephritis (LABN), which is perhaps no more than a preliminary stage in the formation of a renal abscess. Case 1 concerns a LABN, diagnosed by CT scan. The treatment was purely medical and monitoring scans show no anomalies. Case 2 was a gathered abscess, also diagnosed by CT scan, and treated by surgical drainage. The interest of the differentiation between these two types of suppuration is essentially therapeutic. Once gathered, the abscess must be drained surgically, whereas the LABN can be treated medically, with close supervision to ensure complete cure. The differential diagnosis between the two is mainly by scanner, with a study of the respective densities.

Abscess↗

[Adaptation and validation in the French language of the International Score of Symptoms of Benign Prostatic Hypertrophy].

The International Prostate Symptom Score, which was proposed during the First Consultation on Benign Prostatic Hyperplasia in June 1991, was culturally adapted and linguistically validated in French. In a first step, the English version, adapted from the questionnaire developed by the American Urological Association, was translated into French. In a second step, the French version was submitted to a multidisciplinary group who made linguistic improvements. In a third step, the refined version was tested in 30 persons and amended. Finally, the questionnaire was submitted to a linguistic validation study in a representative sample of 100 men aged 65 to 80. The use of this index will allow standardized measurements of urinary symptoms status in patients with benign prostatic hyperplasia.

Aged↗

[The role of endoscopy in the diagnosis and treatment of keratinizing and desquamating malpighian metaplasia of the kidney pelvis].

Keratinized squamous cell metaplasia of the renal pelvis (KSMRP) is a rare lesion, difficult to differentiate from urothelial tumour on the basis of the usual morphological examinations. It is therefore usually diagnosed retrospectively, on histological examination of a nephroureterectomy specimen. However, as its benign nature justifies conservative treatment, preoperative recognition of this lesion is essential. Upper urinary tract endoscopy, which allows diagnosis and treatment of this disease, is therefore very important in this context. Endoscopy is indicated when KSMRP is suspected clinically in a doubtful case of urothelial tumour of the upper urinary tract, in a context of passage of soft stones or a history of renal stones or upper urinary tract infection. Ureteroscopy constitutes the first step to confirm the diagnosis. It must be completed by a percutaneous procedure to eradicate any residual lesion, which could be responsible for recurrence. We report a case of KSMRP in a solitary kidney treated by retrograde and percutaneous endoscopic surgery.

Diagnosis, Differential↗