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Biomedical subjects

P Syrdalen

Publications and source records attributed to P Syrdalen.

At least 19 recordsLinked to original sources

External radiotherapy for circumscribed choroidal haemangiomas using a modified retinoblastoma technique.

This report describes two cases of circumscribed choroidal haemangiomas involving the fovea, complicated by serous retinal detachment. Laser photocoagulation, generally accepted as the treatment of choice for choroidal haemangioma, was considered either to be of no visual benefit or a risk for jeopardizing vision further due to the subfoveolar lesions. Fractionated radiotherapy using a lens-sparing, modified retinoblastoma technique, was given, using circular fields of 15 mm diameter. The dose was 24 Gy in 8 fractions. In both eyes the retina reattached completely. The visual acuity improved markedly in the first, and was restored to the prior level in the second. Normalization of a high intraocular pressure was also achieved in the second case. We believe this method to be a reasonable and effective therapy for some choroidal haemangiomas after careful individual consideration.

Adolescent

[Laser in ophthalmology].

The article presents a brief history of the use of laser in ophthalmology in Norway, from the introduction of the first Argon-photocoagulator in 1972 to the Excimer-laser in 1990. The Argon-photocoagulator is in daily use in all Eye Departments in Norway and the main group of patients treated are those with diabetic retinopathy. Glaucoma has been treated with Argon-laser with good results for the last ten years. YAG-laser, introduced in Norway in 1985, is used to treat secondary cataracts which occur after extracapsular cataract extractions and implantation of artificial lenses. In 1990, the Excimer-laser was introduced for refractive surgery (myopia, astigmatism).

Cataract Extraction

[Retinal detachment after cataract surgery with intraocular lens implantation].

92 pseudophakic retinal detachments were treated in our hospital over a period of six years. These cases are reviewed retrospectively, with special emphasis on the factors that influenced the surgical outcome. The overall rate of success was 80%. Visual acuity was better than 0.1 in 77% of the cases. The major cause of failure was proliferative vitreoretinopathy, which was responsible for seven of ten failures. Postoperative proliferative vitreoretinopathy was the only factor that gave a significantly poorer prognosis after surgical treatment, although the presence of high myopia and preoperative proliferative vitreoretinopathy tended to give a less successful outcome. Likewise, there was a tendency for better prognosis in eyes with posterior chamber intraocular lenses.

Adult

Retinal detachment after YAG-laser capsulotomy.

Preoperative findings and postoperative results in 8 patients with retinal detachment after YAG-laser capsulotomy are described. In this period the over-all incidence of clinical retinal detachment in pseudophakic eyes after YAG capsulotomy in our hospital was 1.0% (2 of 193). Possible relationships between YAG-laser capsulotomy and retinal detachment are discussed. Two risk factors for developing retinal detachment were found in 6 of 8 patients. After surgical repair 7 retinas were re-attached. The final visual acuity was better than 0.5 in 5 patients.

Aged

Ophthalmomyiasis caused by the reindeer warble fly larva.

Two boys with ophthalmomyiasis caused by the first instar larva of the reindeer warble fly Hypoderma tarandi are reported. Both were 9 years old and came from the coast of northern Norway. One had ophthalmomyiasis interna posterior and one eye had been removed because of progressive pain and blindness. Histological examination showed the remains of a fly larva. The second boy had ophthalmomyiasis externa with a tumour in the upper eyelid, and histological examination showed a warble with a well preserved larva. Identification of the parasite in the histological material was based on the finding of cuticular spines and parts of the cephalopharyngeal skeleton identical with those of the first instar larva of H tarandi.

Animals

Intraocular metastasis from cutaneous malignant melanoma.

Metastatic melanoma to the eye can show a number of unusual features. Two cases with intraocular metastases from primary cutaneous malignant melanoma, with a latency of 5 and 16 years, respectively, from excision to debut of ocular symptoms are reported. In the first case, tumour cell invasion of the chamber angle caused an advanced secondary glaucoma. This eye was enucleated some months later when the tumour extended through the sclera despite palliative external radiation therapy. In the other seeing eye, small melanoma metastases were treated with laser. The patient died of systemic involvement. In the second case, a probable melanoma metastasis was revealed by a vitrectomy of a thickened posterior vitreous membrane. Ophthalmoscopy and B-scan ultrasonography 8 months later showed growths projecting 2 mm into the vitreous cavity. Metastases from a malignant melanoma with infiltration of the retina forming nodules, but also affecting adjacent choroid and optic nerve, was disclosed by histology. The patient died of metastasis to the brain.

Anterior Chamber

Long-term visual results after laser treatment of proliferative diabetes retinopathy in childhood onset diabetes.

Ninety-seven laser treated eyes from 55 highly selected childhood onset diabetics (diabetes before the age of 15, proliferative retinopathy before the age of 31, and a follow-up time of at least 5 years) were examined retrospectively. The eyes were divided into two groups, with or without high-risk characteristics according to DRS classification. They were all treated with a blue-green argon laser in the years 1974 to 1981. Of 34 eyes with high-risk characteristics, 12 (35%) were blind (less than FC 1 M) after 5 years. Of 63 eyes without high-risk characteristics, 8 (13%) were blind after 5 years.

Adolescent

Tearing of retinal pigment epithelium after glaucoma surgery.

Tearing of the retinal pigment epithelium following trabeculectomy for chronic open-angle glaucoma in two patients is reported. In one patient, the tear was diagnosed on the 4th postoperative day. It started a few disc diameters above the temporal vascular arcade, crossed the temporal part of the macula and extended to the equator in the lower temporal periphery. At the acute stage, hypotonia and exudative retinal detachment were found. In the other patient, the tear was equatorial extending from the upper nasal to the lower nasal quadrant. At the acute stage, hypotonia and choroidal detachment, but no exudative retinal detachment, were present. After 1 year, the retina was flat in both eyes and no further complications were noted.

Aged

Ophthalmomyiasis interna posterior.

Ophthalmomyiasis interna posterior (OIP) means infection of the posterior part of the eye with the larvae of flies. Few cases have been reported in which the larvae have been removed from the eye and the visual acuity preserved. We report four cases of OIP with living larva in the vitreous cavity. The larvae produced severe uveitis and were removed alive with vitrectomy and a procedure for removing foreign bodies. They were identified as first-stage reindeer warble fly larvae (Oedemagena tarandi). We also observed dead larva in the vitreous cavity of a patient who suffered severe uveitis in 1943, and this eye survived with normal visual acuity. Another patient had a blind eye enucleated and the remnants of a larva were found inside the eye. All patients live in Scandinavia.

Adolescent

Contusion rupture of the globe.

Severe contusion-injuries caused rupture of the globe in 20 eyes in 18 patients. 14 eyes had an open rupture (OR) and primary closure was performed in 13 eyes and one eye was enucleated. Six eyes with closed rupture (CR) had no emergency exploration. In both types of rupture, we intended to do vitrectomy within 14 days. In 12 cases vitrectomy was combined with retinal detachment surgery, lens extraction and gas injection. The upper-lateral quadrant close to the limbus was the most common site of rupture (12 eyes). In 8 eyes the length of the rupture exceeded one quadrant. The lens was extruded in 9 of 14 eyes with OR. Vision preoperatively was in all eyes only light perception. Useful vision (counting fingers or better) was obtained in 7 of 13 eyes with OR and 2 of 5 eyes with CR, excluding 2 totally blind eyes upon admission, one eye in each group. Three patients became totally blind, one patient was hit in her last eye and two patients had bilateral ruptures and these eyes could not be saved.

Adolescent

Pars plana technique for removal of congenital subluxated lenses in young patients.

Lensectomy with the pars plana technique was performed in 16 eyes of 11 patients (2 female, 9 male) with congenital subluxated lenses. Lens subluxation was associated with homocystinuria in 2 patients, Marfan's syndrome in 4, congenital simple ectopia lentis in 2 and without any known heredity in 3 patients. The reason for removal was in all eyes optical disturbances. Five patients were operated on both eyes. All lenses were removed with the Kløti Vitreous Stripper through the pars plana. No complications occurred. Retinal detachment was present pre-operatively in both eyes in one patient with homocystinuria. In the post-operative period, prophylactic photocoagulation and cryotherapy were performed in 7 eyes in 6 patients (6 photocoagulation and 1 cryo). The pars plana technique for removal of clear subluxated lenses in young individuals seems to be the method of choice. Complications are negligible and the method gives excellent optical results.

Adolescent

The use of sodium hyaluronate (Healon) in the treatment of complicated cases of retinal detachment.

Thirty-six eyes with retinal detachment and various degrees of proliferative vitreoretinopathy were operated with conventional buckling techniques and the additional use of intravitreal injected sodium hyaluronate (Healon). Eighteen eyes (50%) had re-attached retina 6 months post-operatively. The re-attachment rate depended upon the severity of the proliferative vitreoretinopathy. Three of 4 eyes with grade B, 4 of 5 with grade C-1, 8 of 13 with grade C-2, 2 of 11 with grade C-3 and 1 of 3 eyes with grade D-1 were reattached. Major complication occurred in 3 aphakic eyes where persistent intraocular pressure rise to 60-70 mmHg necessitated removal of Healon to normalize the intraocular pressure. In one eye Healon passed through a retinal rupture to the subretinal space.

Adolescent

Retinal detachment after intraocular lens implantation.

Between August 1982 and July 1985, 19 eyes were operated for pseudophakic retinal detachment (PRD) (Anterior chamber lens in 13 eyes, posterior chamber lens in 3 eyes and iris supported lens in 3 eyes). The characteristics of these pseudophakic retinal detachments were very similar to those following intracapsular cataract extractions. Retina was re-attached in 18 eyes (95%), in 14 eyes, after one buckling procedure. In 4 eyes, altogether 12 surgical procedures were needed to re-attach the retina. Problems to visualize the peripheral retina, made it necessary to remove the IOL in 3 eyes (2 iris fixated and one in the anterior chamber).

Adult

Pars plana lensectomy.

The results of pars plana lensectomy (PPL) in 36 eyes are reported. The average follow-up time was 9 months (2-24). The optical media became clear in all eyes. Post-operative visual acuity (VA) was greater than or equal to 0.6 in 31 eyes. Two eyes developed serious complications (retinal detachment in 1 eye and neovascular glaucoma in 1 eye). PPL represents minimal risks for the anterior segment, excludes problems with secondary cataract, presents optimal conditions for early contact lens fitting and for necessary treatment in the posterior segment. In the hands of an experienced surgeon PPL is effective and safe and offers an alternative treatment for patients up to the age of 30-35 years.

Adolescent

Light perception in diabetic vitreous haemorrhage and its prognostic value in pars plana vitrectomy.

Ninety-two years with a pre-operative visual function of light perception 6 m or less, were treated with vitrectomy because of diabetic vitreous haemorrhage. The post-operative visual function after 6 months was improved to 5/50-5/5 in 37 eyes and counting fingers from 1 to 5 m in 32 eyes. In 23 eyes the postoperative visual function was unchanged or decreased, and among these were all 7 eyes with pre-operative light perception at 1.5 m or less. No eye with pre-operative light perception at 1.5 or less benefitted from vitrectomy due to extensive retinal damage.

Adult

Vitrectomy in double perforating eye injuries.

The results of 41 consecutive cases of double perforating eye injuries, operated with vitrectomy between December 1975 and December 1982, are reported. Fourteen eyes (34%) obtained a visual acuity of 5/10 or better, and 23 eyes (56%) obtained 5/200 or better. Twenty-eight (68%) developed retinal detachment, and 12 of these were attached by surgery. In this series the pre-operative visual function and the type of injury had a significant effect on the final result. No beneficial effect from early (within 14 days) vitrectomy could be shown.

Adolescent

Combined renal and pancreatic transplantation: effects on advanced diabetic neuropathy and retinopathy.

In this study of 24 uremic diabetic patients treated with combined kidney and pancreas transplantation, the one year patient, kidney and pancreas graft survival was 96, 78 and 55%, respectively. In recipients followed for three months or more, a regression of neuropathy was registered in all patients, whereas improvement in visual acuity was seen only in two patients with simplex type retinopathy. The advanced proliferative retinopathy observed in most recipients at the time of transplantation, was not significantly altered after pancreas and kidney transplantation.

Adult