Biomedical subjects

P Sykacek

Publications and source records attributed to P Sykacek.

2 recordsLinked to original sources

PubMed2005

A friendly statistics package for microarray analysis.

SUMMARY: The friendly statistics package for microarray analysis (FSPMA) is a tool that aims to fill the gap between simple to use and powerful analysis. FSPMA is a platform-independent R-package that allows efficient exploration of microarray data without the need for computer programming. Analysis is based on a mixed model ANOVA library (YASMA) that was extended to allow more flexible comparisons and other useful operations like k nearest neighbour imputing and spike-based normalization. Processing is controlled by a definition file that specifies all the steps necessary to derive analysis results from quantified microarray data. In addition to providing analysis without programming, the definition file also serves as exact documentation of all the analysis steps. AVAILABILITY: The library is available under GPL 2 license and, together with additional information, provided at http://www.ccbi.cam.ac.uk/software/psyk/software.html#fspma

Algorithms↗

PubMed2003

Probabilistic methods in BCI research.

This paper suggests a probabilistic treatment of the signal processing part of a brain-computer interface (BCI). We suggest two improvements for BCIs that cannot be obtained easily with other data driven approaches. Simply by using one large joint distribution as a model of the entire signal processing part of the BCI, we can obtain predictions that implicitly weight information according to its certainty. Offline experiments reveal that this results in statistically significant higher bit rates. Probabilistic methods are also very useful to obtain adaptive learning algorithms that can cope with nonstationary problems. An experimental evaluation shows that an adaptive BCI outperforms the equivalent static implementations, even when using only a moderate number of trials. This suggests that adaptive translation algorithms might help in cases where brain dynamics change due to learning effects or fatigue.

Algorithms↗