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Biomedical subjects

P Stolee

Publications and source records attributed to P Stolee.

22 records · Page 2Linked to original sources

Response bias in a health status survey of elderly people.

This paper compares respondents and non-respondents from the community sample of the Saskatchewan Health Status Survey of the Elderly. Response bias was assessed by comparing the demographic characteristics and use of health care services of the two groups. A stratified two-stage area probability sample was drawn from a comprehensive sampling frame. There were 1614 subjects eligible; interviews were completed with 1267 (78.5%). In the very elderly (85+ years) cohort, disproportionately more urban dwellers and more males were interviewed; the sample was otherwise demographically representative of the elderly population. Non-respondents, especially the very elderly, used significantly more medical services than respondents, and had a higher number of hospital admissions. Non-respondents over age 75 experienced significantly longer average lengths of stay. On average, non-respondents used approximately 15% more hospital days. Non-respondents over age 75 appear to be more likely to experience ill health than respondents. Hence, statistics from this survey are conservative estimates of the ill health of the elderly.

Aged↗

The prevalence of cognitive impairment in an elderly Canadian population.

We investigated cognitive impairment in a study of the health of the elderly population of Saskatchewan. Surveys of elderly persons living at home (n = 1267) and living in long-term care facilities (n = 990) were conducted in 1981. Cognitive impairment was assessed by a short 10-item mental status questionnaire previously validated against a clinical diagnosis of dementia in an elderly Canadian population. The prevalence of clinically significant cognitive impairment was found to increase with age and with dependence level in long-term care facilities. We estimate that 7.8% of the elderly population have cognitive impairment consistent with a clinical diagnosis of dementia. Our estimates are compared with those derived from other studies. These findings affirm the importance of dementia as a cause of dependence in the elderly and the need for long-term care facilities to deal with dementia and its consequences. Also, since at least as many persons with cognitive impairment live at home as in long-term care facilities, health care planners must direct attention to the elderly with dementia at home.

Activities of Daily Living↗

Responsiveness of outcome measures used in an antidementia drug trial.

The responsiveness of outcome measures used in antidementia drug trials has had little formal analysis, but it can be crucial to the interpretation of a medication's effectiveness. The authors report the responsiveness of outcome measures from the Canadian trial of linopirdine, a novel phenylinodolinone, estimated using an effect size statistic. The effect sizes ranged from 0.10-0.26, with the cognitive and functional measures yielding estimates greater than 0.20, a level held to be clinically detectable. All of the standard measures used in this trial, save one, performed better than the global clinical measure. The global clinical measure used in this study may have been too insensitive to detect minimal clinical change.

Activities of Daily Living↗