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Biomedical subjects

P Stefani

Publications and source records attributed to P Stefani.

At least 37 records · Page 2Linked to original sources

Leiomyosarcoma of the kidney: report of two cases with common angiographic findings.

Two cases of renal leiomyosarcoma are described. At angiography both cases presented common findings consisting of: (1) central hypovascularity surrounded by peripheral tumor neovascularity and (2) oval-shaped areas that rapidly filled with contrast medium. This angiographic appearance, although not previously described in such tumors, cannot be claimed to offer a key to preoperative diagnosis because it may be found in the more common hypernephromas with central necrosis.

Adult↗

Angiographic aspects of renal cell carcinoma metastatic to the female genitalia.

Selective angiography of the hypogastric artery was performed in two patients presenting vaginal metastases from renal cell carcinoma, in order to better define the extent of the metastases. In other case left renal angiography revealed an unsuspected metastasis to the left ovary, fed by a middle perforating capsular artery.

Adenocarcinoma↗

Functional renal alterations in chronic liver diseases.

83 patients with chronic active hepatitis (CAH), 38 of them with cirrhosis, were studied and compared with 10 control subjects suffering from chronic persistent hepatitis (CPH). Tubular acidosis frequently was found in our cases. Renal plasma flow and glomerular filtration rate were significantly decreased in CAH when compared with CPH. Selective renal arteriography showed evident decrease of arterial flow in the outer cortex. Selective renal scan with 99mTc microspheres of human albumin showed a frequent escape of the tracer from the kidney to the lung. PGE1 and PGE2 levels appeared higher in the renal artery than in the vein and were significantly more elevated in 9 cases with cirrhosis vs. 13 controls. These results suggest the frequent functional impairment of the kidney also in the early stages of CAH, with an increase of PGE levels and an opening of intrarenal shunts.

Acidosis, Renal Tubular↗