This is a report of analyses of cross-sectional and longitudinal samples of the mental, motor, and social behavior of children with cleft lip and/or palate as measured by the Bayley Scales for Infant Development. Seventy-five patients of the Lancaster Cleft Palate Clinic were the subjects for the sample. The longitudinal sample consisted of 28 of these Ss for whom there were complete data at 6, 12, 18, and 24 months. The results indicated that there were no significant differences in mental and motor functioning. In both analyses, the social behavior of patients with oral-facial clefts was more passive than the Bayley normative sample. The implications of these findings for future research are discussed.

Child Behavior↗

PubMed1977

Inhibition of neutrophil chemotaxis by 4-hydroxycyclophosphamide.

4-Hydroxycyclophosphamide, phosphoramide mustard, and nor-nitrogen mustard are compounds considered as candidates for the biologically active, alkylating metabolite of cyclophosphamide. These compounds were tested for inhibition of chemotaxis in neutrophils from normal human donors. Of those tested, only 4-hydroxycyclophosphamide caused a significant (p less than 0.01) decrease in the chemotactic index. The chemical precursor of 4-hydroxycyclophosphamide, 4-hydroperoxycyclophosphamide, caused a barely significant (p less than 0.05) decrease; 4-ketocyclophosphamide had no effect.

Alkylating Agents↗

PubMed1976

Cleft palate patients--the social work approach.

From birth to maturity, the needs of cleft lip and cleft palate patients change. For such patients, fixed teams of specialists headed by a surgeon may not be the best answer. The authors outline theclinicl characteristics of both deformities and show how social workers are uniquely equipped to coordinate a changing constellation of helpers in an adaptable form of long-term treatment.

Child↗

PubMed1976

The politics of therapeutic nihilism. The new critics of medical care.

Explore the source record for details and available documents.

Adolescent↗

PubMed1975

Factors associated with missed appointments of patients in a cleft lip and palate clinic.

This is a report of the utilization rate of patients in a cleft lip and palate clinic and to ascertain what factors are associated with missed appointments. We had a missed appointment rate of 13.4 percent which compares favorably with those rates reported in the literature. We found that the group of patients who missed all appointments were more highly educated and private payment patients. We also found that our longitudinal patients had a better record of keeping appointments than did other patients.

Appointments and Schedules↗

PubMed1975