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P Skaane

Publications and source records attributed to P Skaane.

At least 37 records · Page 2Linked to original sources

[Investigation of palpable breast tumours. Patient flow and quality assessment of the tripple diagnostic procedure].

The evaluation of patients with a palpable breast lump includes physical examination, mammography, and fine needle aspiration cytology. Combined use of these diagnostic procedures (triple diagnostic) gives nearly the same degree of accuracy as excisional biopsy with a sensitivity of 97-99% in patients with palpable breast carcinomas. Ultrasonography is a valuable adjunct when mammography is normal or nonconclusive and should be the primary imaging modality in patients under 35 years of age with benign findings on physical examination. Ongoing quality assessment of mammography and ultrasonography is mandatory, since the imaging modalities play a central role in the evaluation of patients with lumps in the breast. There are considerable practical problems associated with the medical audit of the triple diagnostic procedure. Aspects of the evaluation of breast lumps and organization of breast imaging centres are discussed in the light of our own experiences.

Biopsy, Needle↗

[Adenocarcinoid (mucinous carcinoid) of the vermiform appendix].

Adenocarcinoid (mucinous carcinoid or goblet cell carcinoid) is an unusual tumour of the appendix with histologic and prognostic features between those of carcinoid and adenocarcinoma. Most patients with adenocarcinoid tumours of the appendix present with symptoms consistent with those of acute appendicitis. We describe a 31 year-old male who presented with such symptoms. Ultrasonography demonstrated an acutely inflamed appendix with a hypoechoic area in the midportion of the appendix, suspicious of a tumour. This rare type of tumour is briefly presented.

Adenocarcinoma↗

[Microductectomy. A simple method for excision of intraductal changes in the breast].

Next to tumour and pain, discharge from the nipples is the most common reason for remitting women to a breast clinic, and comprises 3-6% of the total cause of remittance. We describe a technique for localizing a duct system, where a defect is found by galactography by injection of methylenblue/Isopaque Amin 1:1 in the duct system prior to operation. Ultrasonography can be used to localize the ectatic ducts in cases where there is no secretion on the day of the scheduled operation. The blue colour enables the surgeon to excise the defect duct very precisely. Such a microductectomy preserves breast tissue and gives a better cosmetic result than with complete central ductectomy. We discuss examination and treatment of women with discharge from the nipple.

Breast↗

A personal-computer semiautomated report-coding system for diagnostic mammography.

A computerized report-coding system for diagnostic mammography using a personal computer was developed. Four years' experience with the radiologist-oriented system is presented. The data input time for report generation is in most cases less than 30 seconds by radiologists familiar with keyboard entry. Suspicious and malignant findings are dictated in the conventional way. About 80% of the mammographic examinations at the university Breast Imaging Center were suitable for standardized reporting. Radiologist-generated reports using a personal computer might be an alternative to transcriptionist-oriented systems.

Breast Neoplasms↗

[Ultrasonic examination of the breast].

Ultrasonography can be a valuable adjunct to mammography in the evaluation of breast pathology. Breast sonography can differentiate a cyst from a tumour. Fibroadenomas and carcinomas can often present characteristic ultrasonic features but, as a rule, ultrasonography does not give a confident diagnosis of benign or malignant tumour. Ultrasound-guided needle biopsies and preoperative localization of non-palpable lesions can be performed. Breast sonography should be regarded as an adjunct to mammography. The practical role of ultrasonography in a breast-imaging centre will depend on the quality of the triple diagnostics.

Adenofibroma↗

[Intraoperative ultrasonography of the liver].

Intraoperative ultrasound is the most recent diagnostic tool in liver surgery. It presents the surgeon with a technique that can provide detailed information about liver tumours and their topography prior to surgery. It also provides very good visualization of the vascular tree of the liver. This article gives a detailed description of the technique of intraoperative ultrasound of the liver. It also presents results from two groups of patients: 30 patients who underwent laparatomy for colorectal cancer (n = 16) or for liver tumours (n = 14) were examined by intraoperative ultrasound of the liver. The results were compared with the observations made by preoperative ultrasound examination. In seven patients the intraoperative ultrasound examination showed liver tumors that had not been detected preoperatively. The intraoperative ultrasound was decisive for the operative strategy in three of the patients treated for liver tumours. In one of the patients operated on for colorectal cancer, in whom the intraoperative ultrasound examination revealed a previously unrecognized metastasis, a liver resection is now planned. Our study confirms that intraoperative ultrasound is a valuable form of examination in patients treated for colorectal cancer and is important for deciding the surgical strategy for patients treated for liver tumours.

Adult↗

Value of computed tomography in preoperative evaluation of resectability and staging in oesophageal carcinoma.

OBJECTIVE: To evaluate computed tomography (CT) as a method of staging patients with oesophageal carcinoma. DESIGN: Retrospective study. SETTING: Ullevaal Hospital, Oslo, Norway. SUBJECTS: 85 patients who presented with oesophageal carcinoma between February 1982 and December 1989. INTERVENTIONS: Assessment by CT was made in all patients. MAIN OUTCOME MEASURES: Correlation with findings at operation, and histological examination of operative specimens. RESULTS: From the findings at operation in the 46 patients who were operated on (resection, n = 39; exploration only, n = 7) the sensitivity, specificity, and accuracy of CT staging of the growth were 80%, 91%, and 88%, and when histological confirmation of infiltration was taken into consideration the figures were 25%, 84%, and 54%, respectively. The sensitivity, specificity, and accuracy of CT detection of lymph node metastases were 22%, 95%, and 55%. CONCLUSION: Staging of oesophageal cancer with CT before operation is useful in judging resectability, but the smaller tumours should be assessed with caution. CT is unreliable in the diagnosis of the depth of infiltration and the presence of lymph node metastases compared with histological examination.

Adenocarcinoma↗

Nuclear morphometry of benign and malignant breast lesions.

The mean nuclear area (MNA) of mammary gland epithelium was measured in 403 breast specimens, comprising 239 invasive carcinomas, 49 carcinomas in situ, 45 cases of fibrocystic disease (f.c.d.) with intraductal epithelial hyperplasia, and 60 cases of f.c.d. without intraductal hyperplasia. Normal breast tissue adjacent to other benign or malignant lesions was measured in 170 specimens. Statistical analysis revealed no difference between the MNA of invasive ductal carcinoma and ductal carcinoma in situ. The MNA of lobular and ductal carcinomas were significantly different. Significant differences were also found between ductal carcinoma and the two classes of f.c.d. The MNA of f.c.d. with and without intraductal hyperplasia were also significantly different, the former having the highest MNA. All breast lesions showed MNA significantly higher than that of normal breast epithelium. These findings show that there is a gradual increase in MNA from the baseline value of normal breast epithelium, via fibrocystic disease without and with intraductal proliferation to invasive carcinomas. Measurement of MNA may aid in pinpointing cases of intraductal epithelial hyperplasia with malignant potential.

Breast↗

Peridiverticulitis of the appendix: an unusual ultrasonic "target lesion".

In a 26-year-old man with perforating diverticulitis of the appendix ultrasonography demonstrated a "target lesion" with a hyperechoic center surrounded by a hypoechoic rim similar to the findings commonly seen in benign and malignant conditions of the gastrointestinal tract. This ultrasonographic appearance is quite different from the ultrasonic findings usual in acute appendicitis. We take this to be the first ultrasonic demonstration of appendiceal diverticulitis, and discuss the clinical features, ultrasonic differential diagnosis, and pathology of this condition.

Adult↗

Ultrasonography in patients with suspected acute appendicitis: a prospective study.

The diagnostic accuracy of high-resolution real-time ultrasonography was prospectively studied in 240 patients admitted to the hospital with suspected acute appendicitis. The criteria for ultrasound diagnosis of appendicitis included a sausage-shaped, aperistaltic, hypoechoic structure when imaged along its longitudinal axis, with a target-like appearance on transverse section. The ultrasonographic findings were correlated with surgical-pathological outcome in 82 cases with proven appendicitis, with laparotomy findings in another 21 patients and with clinical follow-up in the remainder. The overall sensitivity, specificity and accuracy of ultrasonography in the diagnosis of acute appendicitis were 78%, 92% and 87%, respectively. The positive predictive value was 84% and the negative predictive value was 88%. Ultrasonography may significantly improve the diagnostic accuracy in patients with suspected acute appendicitis and should be performed in all patients in whom the clinical diagnosis is equivocal. The ultrasonographic findings must be interpreted in light of the clinical findings.

Acute Disease↗

Nonspecific inflammatory pseudotumour of the caecum unrelated to the vermiform appendix.

A case of nonspecific inflammatory pseudotumour of the caecum unrelated to the appendix is reported. Symptomatology, radiological findings, and intraoperative findings suggested a caecal carcinoma. A right hemicolectomy was carried out. Histologic examination revealed an inflammatory mass with abundant fibroblastproliferation and collagen formation infiltrating the muscularis and adjacent pericolic adipose tissue. The caecal mucosa was entirely intact and normal. Histology suggested sclerosing mesenteritis. A correct preoperative diagnosis of nonspecific inflammatory pseudotumours of the caecum is difficult, but awareness of its existence might prevent too radical surgical resections. The differential diagnosis is discussed.

Aged↗

Ultrasound and CT evaluation of pedunculated gastrointestinal lipomas.

Conventional barium examinations and endoscopy can often suggest the presence of submucosal lipomas, but such lipomas are occasionally difficult to differentiate from other submucosal tumors and carcinomas by radiographic examination. Endoscopical biopsies are often inconclusive. A definitive preoperative diagnosis may spare the patient unnecessary or too extensive surgery. The ultrasonic demonstration of a hyperechoic tumor surrounded by normal intestinal walls is highly suggestive of a pedunculated lipoma. CT may confirm the correct diagnosis. Ultrasonic and CT findings in two cases of pedunculated gastrointestinal lipomas are presented.

Aged↗

The histopathology of non-palpable breast lesions detected by clinical mammography.

An histological study of 227 non-palpable breast lesions detected by clinical mammography revealed 64 invasive carcinomas at a mean patient age of 60.5 years. There were 10 carcinomas in situ, mean age 57.2 years. Fibrocystic disease with intraductal epithelial hyperplasia was found in 41 specimens, mean age 54.3 years. Fibrocystic disease without intraductal hyperplasia was found in 57 biopsies, mean age 50.7 years. Histological microcalcifications were found in 113 biopsies, and were considered to be a marker for epithelial proliferation of both benign and malignant kinds. Microcalcifications detectable in histological sections and by mammography differ in size by a factor of 10 or more. This difference has to be considered when comparing histological and mammographic findings.

Adult↗