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Biomedical subjects

P Seror

Publications and source records attributed to P Seror.

At least 37 records · Page 2Linked to original sources

[Sural nerve neuropathy (external saphenous) linked to a disease of the small saphenous vein. Apropos of 5 cases].

Five cases of sural nerve lesion linked to small saphenous vein pathology are reported. They were due to vein stripping (4 cases) and to thrombophlebitis (1 case). The diagnosis was especially delayed in the first 4 cases, as this pathological field is quite unknown. In all the cases, only electrodiagnosis allowed to assess the diagnosis and medical care was sufficient to control the pain of these patients.

Adult↗

Ulnar conduction block at the wrist.

Two cases of ulnar nerve lesions at the wrist are reported. The lesions had an acute onset and exclusively impaired the ulnar motor deep branch. The coexistence of carpal tunnel syndrome in each case allowed an early diagnosis but was somewhat misleading. In both cases, the use of classic motor and sensory conduction studies did not provide clear abnormalities that would have precisely determined the site of the nerve lesion. In both cases, only palmar stimulation of the ulnar motor deep branch showed an important conduction block. This electrodiagnostic finding showed definitively the site of the ulnar nerve lesion at the wrist and excluded proximal ulnar nerve lesions or C8-T1 radiculopathy. In both cases recovery occurred without surgery.

Acute Disease↗

Frequency of sepsis after local corticosteroid injection (an inquiry on 1160000 injections in rheumatological private practice in France).

OBJECTIVES: The principal aims of this study were to determine the frequency of sepsis after local corticosteroid injection (SALCSI), to compare the results with those of the literature and to determine the main factors leading to a decrease in the frequency of SALCSI. METHODS: A retrospective study was conducted among 69 rheumatologists in private practice. Sixteen items were studied and are reported. RESULTS: The mean number of years of private practice in rheumatology was 20.9. The total number of CS injections (CSI) was 1160000 for an average of 809 CSI per year and per therapist. The mean number of CSI performed by one rheumatologist was 16 800. Fifteen SALCSI had occurred, which corresponds to a frequency of 1/77300 CSI. The rate of SALCSI for the older rheumatologists was lower than that of their younger colleagues. The frequency of use of corticosteroid packaged in a sterile syringe (CSPSS) was approximately 85%. Nine out of the 15 cases of sepsis had occurred after the use of CS not packaged in a sterile syringe and six after the use of CSPSS. Thus, the frequency of SALCSI was 1/162000 after the use of CSPSS and 1/21000 after the use of CS not packaged in a sterile syringe. CONCLUSIONS: The mean frequency of SALCSI in Paris and the surrounding area was 1/77300 during the last 21 yr, a decrease since the 1960s and 1970s. This decreased incidence is in part due to the greater experience of the rheumatologist, but even more to the use of CSPSS.

Adrenal Cortex Hormones↗

[Post-partum Parsonage-Turner neuralgic amyotrophy].

Two cases of neuralgic amyotrophy occurred 10 and 15 days after delivery, performed with a peridural anesthesia. The initial diagnosis was a brachial plexus stretching during the labor, even though the first symptoms occurred at least 10 days after the delivery. The diagnosis of neuralgic amyotrophy was based on the onset circumstances, the clinical pattern and the electrodiagnostic data. Better knowledge of this pathology should allow an earlier diagnosis and provide reassurance for the patient concerning delayed but almost constant recovery (90%). This also should help prevent unnecessary complementary examinations and surgery, which is never recommended.

Adult↗

[Results of a neurophysiologic consultation in patients with secondary lymphedema of the arm after breast cancer associated with neurological symptoms].

The aim of this study was to identify the nature of the nerve lesions found in patients with neurological complains and with lymphedema occurring after breast cancer treated by surgery and radiotherapy. Twelve patients treated in a specialised centre for lymphology had clinical and neurophysiological examinations. This study found 9 radiation-induced plexopathies, 1 neoplasic plexopathy, 2 carpal tunnel syndromes (one isolated), 1 cervical root disease and 1 normal examination. The radiation-induced plexopathy is characterised by a chronic neurogenic involvement and the presence of (motor and sensory) proximal persistent conduction blocks. This study demonstrated that it is essential to identify with electrodiagnosis the exact nature of the nerve lesion to determine the most appropriate and effective treatment.

Arm↗

Orthodromic inching test in mild carpal tunnel syndrome.

The Orthodromic inching test of the median nerve at wrist was performed on the dominant wrist of 80 controls and of 100 patients with mild carpal tunnel syndrome defined by the presence of clinical features and normal classical electrodiagnostic tests. In controls the mean conduction delay per centimeter (CD/cm) was 0.184ms and was slightly higher inside than outside the carpal tunnel; the maximal CD/cm (MCD/cm) was never greater than 0.34ms (mean 0.247). In patient the MCD/cm was 0.36 ms or more in 96 patients. This abnormality was located within the carpal tunnel in 92% of cases. Outside the entrapment site CD/cm values remained normal and similar to those found in the controls. On the whole, this results in an overall specificity of 100% and sensitivity of 96% for the Orthodromic inching test.

Adult↗

Pregnancy-related carpal tunnel syndrome.

Clinical and electrophysiological features were studied in 52 cases of carpal tunnel syndrome (CTS) associated with 30 pregnancies. The duration of symptoms was less than 3 months before electrodiagnosis was performed. This study revealed a higher incidence of persistent, painful diurnal symptoms in pregnancy-related CTS (PRCTS) than in idiopathic CTS. PRCTS usually occurs for the first time (de novo) (24/30 cases), in primigravidas (15 cases) as well as multigravidas. The onset of symptoms was in the first or second trimester in 11 women, the third trimester in 12 women, or the post-partum period in seven women. Nerve conduction studies demonstrated evidence of an acute median nerve lesion at the wrist with motor and/or sensory conduction blocks in 20/30 women and severe denervation signs in five women.

Adult↗

[Pinch deficit of the thumb-index finger due to a lesion of the anterior interosseous nerve. Apropos of 17 cases].

We report 17 cases of abnormal pinch due to anterior interosseous nerve (AIN) palsy. The AIN lesion was complete with palsy of flexor pollicis longus (FPL) and Flexor digitorum profondus of the second digit (FDP2) in nine cases. A partial lesion with FPL palsy was observed in four cases, and FDP2 in four other cases. Three of this eight cases were initially considered to be tendon ruptures. Electrodiagnosis assessed AIN lesion and respect of the main median trunk in all cases. Pronator quadratus examination provided the diagnosis in 14/17 cases and FPL or FPD2 examination established the diagnosis in the other 3 cases. Associated nerve lesions were found in four cases. Pinch grip was spontaneously recovered in 9/10 cases. The AIN lesion was due to compression in 3 cases and to mononeuritis such as Parsonage Turner neuralgic amyotrophy in 14 cases. As 2/3 cases of compression resolved spontaneously, surgery indications are rare and should not be considered before 12 to 16 months when the lesion is not traumatic.

Adolescent↗

[Carpal tunnel syndrome in pregnancy].

Analysis of 20 patients with 34 carpal tunnel syndromes (CTS) showed that CTS in pregnancy occurs generally between 30 and 40 years of age in both primiparous (n = 7) and multiparous (n = 13) women. The syndrome usually is most bothersome during the third trimester of pregnancy (n = 10) or during puerperium (n = 7). Clinically, CTS in pregnancy is very different from idiopathic CTS. Paresthesia frequently occurs during the daytime or is permanent and usually more troublesome than phenomena occurring at night. The Weber and Semmes Weinstein test, an objective measurement of hypoesthesia, is often positive. The electrophysiological findings are more serious and are different from those observed in idiopathic CTS. Mean nerve conduction velocity in the median nerve measured at the wrist is comparable in the two forms, but the frequency of neurogenic pattern is higher in pregnancy CTS. Conduction blocks are also much more frequent and concern motor (18%) or sensory (44%) conduction. These conduction blocks result from acute compression of the nerve due to hormone-dependent tenosynovitis. Infiltrations are effective in 85% of the cases, but in some forms with very serious axonal loss, surgical release is justified.

Adult↗

[Postoperative amyotrophic cubital neuralgia: 4 cases].

Four cases of post-operative ulnar nerve mononeuropathy are reported. In all the cases a severe sensory and motor loss was strictly limited to ulnar nerve territory. The electrophysiological examination: needle examination, motor and sensory nerve conduction studies and even more somatosensory potential evoked from ulnar nerve after stimulation above elbow allowed to eliminate a lesion at the elbow and to asses the lesion at wrist, arm, axilla or plexus. Full recovery occurred once and partial recovery twice. We considered that these ulnar lesions are neuralgic amyotrophies of Parsonage and Turner according to the epidemiological, clinical, evolutive and electrophysiological data.

Adult↗

The axonal carpal tunnel syndrome.

Five patients with typical unilateral carpal tunnel syndrome features were studied. Each patient had a normal electrodiagnostic evaluation, including needle examination (C5 to C8T1), distal motor latency, palm to wrist orthodromic sensory conduction velocity, and special tests: median-ulnar latency difference of the 4th digit, palmar centimetric technique. Only a new test, the orthodromic sensory ultra distal test of all the digits, revealed a significant axonal loss (60-90%) in at least two median digits allowing the diagnosis of median nerve impairment. These findings led us to propose the term, axonal carpal tunnel syndrome for this early stage of the disorder.

Adult↗

Anterior interosseous nerve lesions. Clinical and electrophysiological features.

Lesions of the anterior interosseous nerve in the forearm are rare and often misdiagnosed as tendon injuries. A consecutive series of 13 patients with this condition referred for electrodiagnosis is reviewed. Only three had originally a correct clinical diagnosis and three were initially considered to have tendon ruptures. Five cases were of mechanical origin and seven due to 'neuritis'. All showed electrophysiological abnormalities, most commonly involving the pronator quadratus. Late spontaneous recovery was common, and only one case had surgical exploration.

Adult↗

[Somesthetic evoked potentials and serial motor evoked potentials in the study of proximal peripheral nerve conduction. Apropos of 7 cases].

The study of proximal motor and sensory nerve conduction in the thoracic outlet syndrome is still difficult and laborious in 1994. However, these conductions can be measured at different levels by means of somaesthetic evoked potentials and motor evoked potentials, when one takes the time to perform them. The study in normal subjects demonstrates that the proximal sensory and motor conduction delays are approximately 3.2 ms and are therefore comparable to that of the median nerve at the wrist. The study of 7 cases related to various diseases shows that these techniques, performed after electromyogram of both upper limbs, an essential prerequisite to their interpretation, are able to clearly demonstrate abnormalities of proximal conduction in patients suffering from of a scalene syndrome, a cervical epiduritis, radiation plexopathy, hereditary sensible to pressure neuropathy, motor neuropathy with persistent multifocal conduction blocks, or, on the contrary, may confirm the normality of conduction, for example in anterior horn disease.

Adult↗