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Biomedical subjects

P Selosse

Publications and source records attributed to P Selosse.

At least 37 records · Page 2Linked to original sources
PubMed1980

Pituitary abscess. Case report.

A case of pituitary abscess is reported in which the diagnosis was made during surgery. The difficulties in diagnosis and management of patients with this rare entity are stressed.

Abscess↗
PubMed1977

Oculomotor anomalies in sellar and parasellar pathology.

The authors report 19 cases where diplopia was the initial symptom of sellar pathology, Additionally, 5 cases with doubtful, diagnosis are discussed. Considering a series of 134 adenomata, the onset in 7 cases was intermittent diplopia with involvement of the third nerve.

Abducens Nerve↗
PubMedDate not supplied

Gadolinium-DOTA enhanced MR imaging of intracranial lesions.

Gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (Gd-DOTA) is the first of a new class of macrocyclic paramagnetic magnetic resonance (MR) contrast agents (gadolinium cryptelates) to be used in clinical practice. Gadolinium-DOTA possesses relaxation properties similar to those of gadolinium diethylene triamine pentaacetic acid (Gd-DTPA). We report our initial clinical experience in 38 patients with intracranial lesions studied with MR before and after injection of Gd-DOTA. Diseases included primary and metastatic brain tumor, cerebral infarct, vascular malformation, meningioma, hemangiopericytoma, schwannoma, and pituitary macroadenoma. Gadolinium-DOTA was administered intravenously in a dosage of 0.1 mmol/kg body weight. All studies were performed on a superconductive 0.5 T system. As compared to noncontrast T1- and T2-weighted images (WI), Gd-DOTA enhanced T1 WI were useful in defining the anatomy of malignant intraaxial tumors (high-grade glioma, metastasis) and in tumor versus edema differentiation. Low-grade gliomas did not enhance; in these cases the precontrast T2-weighted sequence was found to be more informative. In post-operative patients, Gd-DOTA allowed us to demonstrate residual tumor or tumor recurrence. Extraaxial tumors (meningioma, hemangiopericytoma, neuroma) enhanced markedly, presumably reflecting tumor vascularity. In our experience, the use of Gd-DOTA improves the anatomic definition of cerebral lesions and in some cases increases both MR sensitivity and specificity. We found Gd-DOTA to be a well tolerated and effective paramagnetic contrast agent. Gadolinium-DOTA can be considered as an alternative water-soluble MR contrast agent to Gd-DTPA.

Adult↗
PubMedDate not supplied

Transcranial Doppler sonography.

A general review of the physical principles and the applications of transcranial Doppler (TCD) sonography is given. This new non-invasive technique is presented as an important diagnostic tool in neurology, neurosurgery and intensive care medicine. The applications are documented using our own patient material.

Cerebrovascular Circulation↗
PubMedDate not supplied

Transcranial Doppler sonography in subarachnoid hemorrhage.

Ten patients presenting a subarachnoid hemorrhage (SAH) due to rupture of a middle cerebral or an anterior communicating aneurysm are presented. Transcranial Doppler (TCD) values are obtained at different time intervals after SAH. The correlation of TCD values, vasospasm and clinical course is discussed.

Adult↗