Search PubMed⌕ Search

Biomedical subjects

P Seghizzi

Publications and source records attributed to P Seghizzi.

26 records · Page 2Linked to original sources

Study of lung reactions in six asymptomatic workers occupationally exposed to hard metal dusts.

The description of one case of pulmonary fibrosis in a group of workers occupationally exposed to hard metal dusts with high concentrations of cobalt (50-90%), followed for five years, prompted us to perform a cytological examination on the bronchoalveolar lavage fluid plus determination of the lymphocytic subpopulations in six asymptomatic workers with the longest exposure. Bronchoalveolar lavage performed 16 hours (3 cases) or 48 hours (3 cases) after the end of the workshift showed a lymphocytosis with inversion of the helper/suppressor ratio in 3 cases. This demonstrates an immune response at deep lung level. No difference was observed between a subject with ascertained interstitial fibrosis and the other subjects. Furthermore, bronchoscopy revealed marked inflammatory reaction of the tracheobronchial mucosa.

Adult↗

[Clinico-anamnestic survey in health professionals exposed to volatile anesthetics].

The authors describe the results of a preliminary clinical survey of a group of 220 health workers, physicians and 151 nursing and auxiliary staff members of a large regional hospital in Lombardia, who are exposed to volatile anaesthetics. Contact dermatitis, varices of the legs and arthrosis, particularly that of the cervical and lumbar tract, are the most frequently reported disease in our population. In 75% of cases these disturbances arose after the beginning of the job working in the operating-theatres. When compared with a control group there was a statistically significant difference for contact dermatitis (p less than 0.01) and cervical tract arthrosis (p less than 0.02). The statistical comparison among the subjects exposed to the anaesthetics gases, who were stratified on the basis of the level of exposure and of seniority, confirms a higher prevalence of symptoms due to a reduction of alertness and of psychological and psychomotorial performances in the more exposed personnel. The comparison between female staff exposed and not-exposed to the gases did not show an increase of abortivity, while a statistically significant difference was evident between the female staff (either exposed or not-exposed) and the wives of male workers not exposed to the anaesthetics gases.

Adult↗

[Sanitary surveillance of workers occupationally exposed to volatile anesthetics: proposal for a computerized program for data collection and processing].

The aim of this work is to present a computerized program for an epidemiological evaluation of the data relevant to workers occupationally exposed to anesthetic gases and of the related occupational risks. The great handiness, the speed of execution, the possibility of carrying out researches by mean of multiple variables correlation and the prompt availability of the data, are the distinguishing features of this program.

Air Pollutants, Occupational↗

[Epidemiology of ischemic cardiopathy in a large iron foundry].

This work examines the coronary disease distribution in a large iron-foundry (7000 workers) with different ways of work and productive technologies, taking into consideration the high incidence and the multiple etiology of risk factors of cardiovascular diseases in the general population. In particular we studied the frequency of coronary disease and its consequence on the workers as far as retirement, death and job modification are concerned.

Coronary Disease↗

[Individual dosimetry and biologic monitoring of workers exposed to low concentrations of aniline].

Low aniline vapours concentration exposure has been studied through either active or passive individual dosimeter, in a group of workmen employed in the production of an antioxidant for the rubber industry. We collected 28 samples, confirming the clear correlation existing between the two methods which was already demonstrated in a previous work. We newly suggest the usefulness of the individual passive dosimeter instead of the traditional vacuum pump system. Meanwhile we have determined bound and free aniline and total aromatic amines, with and without an extractive method on column, on urinary samples collected before and after the workshift. The values so obtained have been compared with the results of the active individual dosimetry. We could demonstrated a statistical significative correlation only between urinary aniline determination and the level of exposure, so confirming the value of this parameter as biological indicator of occupational exposure.

Air Pollutants, Occupational↗

[Repetitive movement of the upper limbs: results of exposure evaluation and clinical investigation in wood sanding in Bergamo].

The authors report their findings regarding a risk assessment study and clinical tests carried out among a group of 121 workers whose job was to sandpaper and buff timber products. The results of the risk assessment indicate that the job in question is at significant risk for the development of WMSDs in relation to the principal risk factors (repetitiveness, force, posture, short recovery periods). The clinical tests, undertaken by medical staff, complied with the anamnestic models proposed by EPM. The results showed that 21 workers were above the anamnestic threshold, and were thus referred for specialist examinations. As a result of the latter, the relevant diagnoses were made. A positive correlation was reported between the occupational exposure level and the clinical abnormalities detected.

Adolescent↗