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Biomedical subjects

P Schulz

Publications and source records attributed to P Schulz.

At least 127 records · Page 7Linked to original sources
PubMed1981

[The psychological consequences of prognathism (author's transl)].

In a prospective study of 54 prognathic patients the psychological effects of this condition, which occurs typically at puberty, were investigated in postoperative follow-up examinations and the psychological effect of a corrective operation investigated. For this purpose standardized questionnaires and a semistructured psychiatric interview were used. The hypothetically expected personality disturbance of a "dysmorphophobia" was found in only some of our patients. With an inconspicuous premorbid personality they reacted to the psychological trauma of their facial deformity with depressive crises of self-assessment in the occupational and private spheres. Here, convincing postoperative improvements occur beside which the "psychological scars" are still recognizable owing to the earlier deformity.

Adult↗
PubMed1981

Cytological findings in cases of marsupialized odontogenic cysts. A contribution to early diagnosis of malignant changes.

The early diagnosis of a malignant or premalignant change in cyst epithelium in the follow-up control of fenestrated odontogenic cysts can easily be made using exfoliative cytology. This investigation reveals the findings in 408 cyto-smears of 89 patients. Only in one case was the cyst epithelium free of pathological signs. 405 cyto-smears showed very variable inflammatory changes. The smears of one patient were typical for an ameloblastoma, microscopically smears of three patients showed keratinised epithelium. If the radical removal of an odontogenic cyst is not possible, cyto-smears should be applied and randomly repeated. Thus the possible change of cyst epithelium via inflammation or dysplasia to malignancy can be detected and treated earlier.

Adolescent↗
PubMed1980

[A retrospective study of carcinomas of the oral cavity: a preliminary report (author's transl)].

UNLABELLED: The German-Austrian-Swiss Research Team on Maxillofacial Tumours is investigating a series of 585 carcinomas of the oral cavity, lips and oropharynx by biostatistical methods. The aim of the study is the determination of relevant prognostic symptoms of oral cavity carcinomas, classification of the series on the basis of these symptoms, the determination of therapeutic efficacy and the assessment of collective and individual prognosis. PRELIMINARY RESULTS: 1. Factors of prognostic relevance are probably only tumour size and intensity of regional metastases. 2. The classification of the series becomes problematic due to the lack of relevant prognostic factors.

Female↗
PubMed1980

Carcinoma of the oral cavity: on the prognostic significance of the primary tumour site (by organs) in the oral cavity.

The prognostic significance of so-called organ sites was investigated in 585 cases with carcinoma of the oral cavity and lips. For the subsamples studied the numerical distribution of TNM categories, life tables and life table comparisons were computed. This produced the following results: 1. There is no demonstrable difference in prognosis between identical T catagories in the organs of the oral cavity. 2. In some cases there is a significant difference between identical N categories in organs of the oral cavity. In the No category this is, however, attributable to the substantial differences in the numerical distribution of T categories. By contrast, a logical explanation for the computationally demonstrable significant differences in the Nx category is not available. The problem is currently being investigated. 3. An assessment of identical TN combinations in the "organs" of the oral cavity proved to be impossible on account of the inadequate number of cases available. The so-called "organ localization" of primary tumours in the oral cavity need not - at least for the time being - be accorded any prognostic relevance. The findings should, however, be re-examined on the basis of greater numbers.

Actuarial Analysis↗
PubMed1980

[Identification from bite marks].

Criteria to be considered for establishing the guilt or innocence of a possible offender on the basis of bite marks on the skin of the murder victim were presented using four analyses of bite marks on murder victims. The bite marks must be identifiable; a clear 1:1 photograph should be made which is then compared with impression of a model of the suspect's bite. These impressions are made with graphite on, for example, the surface of a balloon or modelling clay. The evidence provided by a distinct bite mark is almost as conclusive as a fingerprint. Using only the bite mark photographs, the forensic-stomatologic evaluation influenced the course of argumentation in the legal proceedings of three of the four cases discussed; the evaluation was central for the proceedings in one case.

Adult↗
PubMed1979

Carcinoma of the oral cavity: on the prognostic significance of the primary tumour site (by levels and areas).

The prognostic significance of primary tumour site in carcinomas of the oral cavity was investigated in a series of 585 cases. For the subsamples (levels and areas of oral cavity) studied, the numerical distribution of TNM categories, life tables and life table comparisons were computed. This produced the following results: Given an identical extension and analogous metastazising rate, there is no computationally demonstrable difference in prognosis between primary tumours sited at different levels and areas of the oral cavity. The exception are the T1Nx categories, for which a difference exists between precanine and retromolar sites. These results should be re-examined on the basis of a larger series.

Actuarial Analysis↗
PubMed1979

Diflunisal, a new-acting analgesic and prostaglandin inhibitor: effect of concomitant acetylsalicylic acid therapy on ototoxicity and on disposition of both drugs.

Intermittent and concomitant acetylsalicylic acid (ASA) therapy was superimposed onto a 21-day regimen with diflunisal 250 mg b.i.d. Low doses of ASA (600 mg single dose or 300 mg q.i.d.) did not influence signficantly diflunisal blood levels whereas a 600 mg q.i.d. dosing caused a small significant drop, especially at trough level. This drop is not expected to be clinically significant. No ototoxicity could be demonstrated with any treatment of diflunisal though four of fourteen subjects reported mild tinnitus during concomitant therapy at the higher doses of ASA. Diflunisal at 375 mg b.i.d. failed to alter the metabolism of a single dose of labelled ASA (600 mg) as judged by plasma levels, urinary excretion and plasma binding. Daily urinary excretion of prostaglandins E1 and E2 major metabolite was decreased by about 70% by diflunisal.

Adult↗
PubMed1978

Refined mapping of the gene for glutathione reductase on human chromosome 8.

Activity of the enzyme glutathione reductase (EC 1.6.4.2) in erythrocytes and fibroblasts of a patient with karyotype 46, XY, del(8) (pter-p212:) was found to be in the normal range. With results from other laboratories, this allowed a more precise mapping of the gene for this enzyme in the region 8p2100-8p212.

Child↗
PubMed1978

[The effect of the shape of aluminum oxide-ceramic implants on its staying power in the dog mandible].

Investigations were carried out on implants of Al2O3 ceramic as secondary single toothe replacement in the lower jaw of young Beagle test dogs. Two basically different forms with altogether 7 variations were tested: the first three types of implants had conical roots and a further 4 had cylindrical roots. Common to all 7 types was an implantation shoulder which was tested for its ability to conduct the masticatory force via the cortical substance to the mandibular bone. All implants are at least under indirect masticatory strain; type 80-40-027-00 was directly under strain: part of the implant, shaped like a premolar protrudes through the gum directly into the oral cavity. Preliminary results show that cylindrical root shapes stood the test well. Their length was of no great importance. Conical root shapes without special provision of retention are not suitable. Firm positioning of the implant during introduction is of prime importance. A cortically placed implantation shoulder is not suitable for the conduction of the masticatory pressure into the mandibular bone in dogs.

Aluminum Oxide↗
PubMed1977

New chromosomal malformation syndromes. I. Partial monosomy 8p. An attempt to establish a new chromosome deletion syndrome.

A mentally retarded 8-year-old boy with a de novo partial monosomy for the short arm of the No. 8 chromosome is described. Based on G-banding analysis, the patient's karyotype was identified in lymphocytes and skin fibroblasts as 46,XY,del(8) (pter leads to p21:). No chromosomal abnormalities were found in the phenotypically normal mother, father and sister of the propositus. Four further cases described in the literature indicate that partial monosomy of the short arm of the No. 8 chromosome might be associated with a syndrome characterized by the following stigmata: mental retardation, slow growth, high forehead, broad chest, wide-set nipples, pulmonary stenosis with atrial and/or ventricular septal defect, hypoplasia of the genitalia, dermatoglyphic stigmata.

Child↗
PubMed1977

[The possibility of oral rehabilitation of the handicapped under anesthesia].

In addition to technical and personnel requirements, clinical experience is necessary for oral rehabilitation of handicapped patients under general anesthesia. As our investigation has shown, the dental measures conceivable under legal aspects and theoretically feasible under general anesthesia, are almost exclusively limited to uncompromising, dental surgical reconstruction, if possible in one session. Conservative measures show a lasting success in few cases only, especially in occlusal acrylic and amalgam fillings of handicapped persons of sufficient intelligence and personal oral hygiene. Treatment under general anesthesia is inevitably indicated in imbeciles, the feeble-minded, spastics, epileptics, and sometimes in mongoloids. The patient's wish or that of his companion are not sufficient, nor the lack of will or obstinacy. Only after all other means failed, should oral rehabilitation be performed under general anesthesia.

Anesthesia, General↗