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Biomedical subjects

P Sarda

Publications and source records attributed to P Sarda.

82 records · Page 5Linked to original sources

[Reinfection after rubella and congenital polymalformation syndrome].

A case is reported of a term newborn with intra uterine growth retardation and numerous malformations such as complex heart disease, abnormalities of distal limbs, cleft palate. Death occurred after two days. The diagnosis of rubella embryopathy was confirmed by the following criteria: a high level of rubella antibodies in mother and newborn (1/1000) an isolation of rubella virus from the infant's urine. Diagnosis of rubella after reinfection was documented by a high level of antibodies in the mother three years before this pregnancy. Other observations reported in literature confirm the extreme rarity of congenital rubella after reinfection.

Abnormalities, Multiple↗

[Fatal Marfan syndrome in the neonatal period].

Case-report of neonatal Marfan Syndrome with at birth the following observations: arachnodactyly, excessive length of arm, cardiac anomalies with hemodynamic troubles leading to death within 4 days. Anatomical data of the postmortem examination and histologic anomalies of the aorta confirm the diagnosis. No case of Marfan syndrome are to be found among forebearers. These characteristics underline the rarity, the gravity of the pronostic and the often sporadic appearance of the Marfan syndrome when revelated in the neonatal period.

Abnormalities, Multiple↗

The importance of an antenatal ultrasonographic diagnosis of correctable fetal malformations.

This study describes the importance of an early echographic examination during pregnancy for the antenatal diagnosis of fetal anomalies potentially correctable after birth. During a period of 18 months there were 28 cases. In seven fetuses a gastrointestinal malformation was diagnosed between 20 and 36 weeks of gestation; there were 16 cases of urogenital anomalies detected between 19 and 38 weeks of gestation, and five other various malformations were detected between 17 and 33 weeks of gestation (two diaphragmatic hernias, one congenital heart malformation, and two cases of benign tumors). This study suggests that ultrasonic antenatal diagnosis could result in a decrease in the morbidity of congenital malformations that are correctable if the delivery is carried out in a high-risk perinatal center.

Congenital Abnormalities↗

[Streptococcus group B neonatal infection and postnatal diaphragmatic hernia].

The authors report a case of post natal hernia with group B beta hemolytic streptococcus infection. The frequency of such an association compared to the rarity of delayed onset congenital diaphragmatic hernia may constitute a reflexion subject. The literature is reviewed and a concept of pathogenesis is discussed.

Anti-Bacterial Agents↗