Biomedical subjects

P Sangueza

Publications and source records attributed to P Sangueza.

6 recordsLinked to original sources

PubMed1993

Mucocutaneous leishmaniasis: a clinicopathologic classification.

BACKGROUND: Leishmaniasis, a chronic parasitic disease transmitted by Phlebotomus sandflies, affects millions of patients. Mucocutaneous leishmaniasis caused by Leishmania brasiliensis is endemic in much of South America. OBJECTIVE: Our purpose was to develop a system for staging mucocutaneous leishmaniasis on the basis of clinical, histopathologic, epidemiologic, and immunologic criteria. METHODS: Seventy-five Bolivian patients with mucocutaneous leishmaniasis were evaluated by history and physical examination; cutaneous, mucosal, and bone marrow biopsy specimens; and immunologic assessment. RESULTS: Mucocutaneous leishmaniasis may progress through three clinical stages: (1) the primary or cutaneous, (2) the cicatricial, and (3) the secondary or mucocutaneous stages. The primary stage can be further subdivided into three phases: lymphoplasmocytic, tuberculoid, and diffuse cutaneous phases. The secondary stage can also be subdivided into three phases: edematous, granulomatous proliferative, and granulomatous necrotizing stages. CONCLUSION: A classification or staging system enhances the ability to evaluate patients with mucocutaneous leishmaniasis and determine more accurately their prognosis and treatment.

Adult↗

PubMed1992

Rhabdoid tumor of the skin.

A tumor in the skin of a 42-year-old man was analyzed by light and electron microscopic study and immunohistochemistry. The tumor cells were large and contained eosinophilic, periodic acid-Schiff (PAS)-positive inclusions in the cytoplasm. Immunohistochemically, the neoplasm was positive for intermediate filaments, cytokeratin, vimentin, desmin, and alpha-1-antichimotrypsin, and negative for S-100 and leukocyte common antigen (LCA). Ultrastructurally, the cytoplasm and cellular processes of the cells were inundated with intermediate filaments, some of which were tightly bundled. Junctional complexes and secretory granules were absent. These features suggest a rhabdoid tumor: a malignant tumor of uncertain origin.

Adult↗

PubMed1992

Intravascular lymphomatosis: report of an unusual case with T cell phenotype occurring in an adolescent male.

Intravascular lymphomatosis is a rare disorder which most often occurs in the elderly. The overwhelming majority of the cases studied immunophenotypically have expressed a B cell phenotype. We report an unusual case of T cell intravascular lymphomatosis occurring in an adolescent male.

Adolescent↗

PubMed1990

Rhabdomyoma of the tongue.

Rhabdomyomas, which are rare striated muscle neoplasms, may occur on oral or genital mucosal surfaces as well as on the skin. Little discussion of rhabdomyomas occurs in any dermatology or dermatopathology literature. We report an 84-year-old patient who had a rhabdomyoma of her lateral tongue and discuss the clinical and histologic characteristics of this unusual type of benign neoplasm.

Aged↗

PubMed1981

[Lipoidproteinosis].

We report the first case of L.P. in our country with typical lesions of skin, pharyngeal and laryngeal mucous membranes. Our observation did not indicate any history of consanguinity nor family incidence, nor visceral engagement. The hepatic biopsy was normal. Connected with the main illness we found a radiopaque area in the right frontal bone which engaged the interior and exterior walls, and a calcification nodule in the base of the right maxillary sinus.

Aged↗

PubMedDate not supplied

Hallermann-Streiff-Francois syndrome.

This is a typical case of Hallermann-Streiff-Francois Syndrome in which the glaucomatous complication may be caused by developmental malformations in the anterior segment of the eye. Bilateral trabeculectomy succeeded in controlling the tension after a follow-up of two years. Glaucomatous complication seems to be frequent and as important as the other described cardinal symptoms. The histologic examination of the skin confirmed the atrophic changes that were observed clinically.

Adolescent↗