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Biomedical subjects

P Saiviroonporn

Publications and source records attributed to P Saiviroonporn.

7 recordsLinked to original sources

Interactive 3-dimensional segmentation of MRI data in personal computer environment.

We describe a method of interactive three-dimensional segmentation and visualization for anatomical magnetic resonance imaging (MRI) data in a personal computer environment. The visual feedback necessary during 3-D segmentation was provided by a ray casting algorithm, which was designed to allow users to interactively decide the visualization quality depending on the task-requirement. Structures such as gray matter, white matter, and facial skin from T1-weighted high-resolution MRI data were segmented and later visualized with surface rendering. Personal computers with central processing unit (CPU) speeds of 266, 400, and 700 MHz, were used for the implementation. The 3-D visualization upon each execution of the segmentation operation was achieved in the order of 2 s with a 700 MHz CPU. Our results suggest that 3-D volume segmentation with semi real-time visual feedback could be effectively implemented in a PC environment without the need for dedicated graphics processing hardware.

Adult↗

Real-time interactive three-dimensional segmentation.

RATIONALE AND OBJECTIVES: The authors developed a real-time, interactive three-dimensional (3D) segmentation pipeline that uses relatively low-level segmentation operations and provides two-dimensional and 3D visualization through a user-friendly graphical interface. MATERIALS AND METHODS: The low-level segmentation processes were implemented on a massively parallel computer; the graphical user interface was written with a public domain software toolkit. Since their implementation 2 years ago, these segmentation tools have been applied to approximately 300 computed tomographic and magnetic resonance imaging data sets. Two typical clinical cases are presented to demonstrate their applications. RESULTS: The entire processing pipeline can be executed in a few seconds. The tools are simple to learn because they involve the use of low-level procedures and a user-friendly graphical interface with a short interactive response time. Segmentation of the bones, aorta, kidneys, and kidney cysts in case 1 could be performed in about 16 minutes. The time needed to segment each organ in case 2 ranged from about 15 minutes for the skin and brain to about 1 minute for the tumor. CONCLUSION: Satisfactory results can be obtained in a relatively short time with the real-time interactive 3D segmentation system. Operation of the system can be easily learned by a wide variety of nonspecialized users with some medical background.

Algorithms↗

Non-Fourier encoding with multiple spin echoes.

The advantages and limitations of multiple spin-echo sequences for non-Fourier encoding are investigated. Complications caused by improper encoding of alternate magnetization pathways due to imperfect refocusing pulses are analyzed. It is shown that mirror image ghosts result if the encoding RF pulse matrix is real-valued. These ghosts can be avoided as long as the rows of the RF pulse matrix are conjugate symmetric, which implies that spatial profiles are real valued. Non-Fourier encoding using bases derived from wavelet, Hadamard, and other real-valued orthogonal functions does not result in a mirror ghost artifact. A RARE sequence for non-Fourier encoding has been implemented on a clinical imaging system and successfully applied for brain imaging.

Artifacts↗

Monitoring and visualization techniques for MR-guided laser ablations in an open MR system.

Our purpose was to develop temperature-sensitive MR sequences and image-processing techniques to assess their potential of monitoring interstitial laser therapy (ILT) in brain tumors (n = 3) and liver tumors (n = 7). ILT lasted 2 to 26 minutes, whereas images from T1-weighted fast-spin-echo (FSE) or spoiled gradient-recalled (SPGR) sequences were acquired within 5 to 13 seconds. Pixel subtraction and visualization of T1-weighted images or optical flow computation was done within less than 110 msec. Alternating phase-mapping of real and imaginary components of SPGR sequences was performed within 220 msec. Pixel subtraction of T1-weighted images identified thermal changes in liver and brain tumors but could not evaluate the temperature values as chemical shift-based imaging, which was, however, more affected by susceptibility effects and motion. Optical flow computation displayed the predicted course of thermal changes and revealed that the rate of heat deposition can be anisotropic, which may be related to heterogeneous tumor structure and/or vascularization.

Brain Neoplasms↗

Digital wavelet-encoded MRI: a new wavelet-encoding methodology.

A new digital wavelet-encoding method for MRI is described. The method differs from previously described wavelet-encoding approaches, because the point-spread function is made independent of the wavelet basis used. This has a significant practical advantage, because wavelet bases can now be considered that would otherwise be excluded due to the difficulty of precisely exciting wavelet-shaped RF profiles. The method has been implemented on a clinical MRI system, and human images are presented.

Brain↗

MRI monitoring of laser ablation using optical flow.

The optical flow method is used for visualizing and quantifying the dynamics of tissue changes observed by MRI during thermal ablations. An approach was implemented for parallel two-dimensional optical flow calculations including the replacement of spurious velocities. Velocity magnitude results were found to be accurate in low-noise cases in tests using series of synthetic images. Optical flow results are presented from thermal ablation experiments utilizing a homogeneous polyacrylamide gel phantom and heterogeneous rabbit liver tissue in vivo, exhibiting heating and cooling with the accompanying quantitative characterization of the dilation and contraction of the thermally affected region. Results demonstrate that optical flow is capable of noninvasive real-time monitoring and control of interstitial laser therapy (ILT).

Acrylic Resins↗