Effect of ultraviolet radiation on the oxidation of certain Krebs cycle substrates in Vibrio cholerae.
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Citric Acid Cycle↗
Biomedical subjects
P Sagar
Publications and source records attributed to P Sagar.
In vitro insulin action on different ATPases of erythrocyte membranes in normal and diabetic rats.
The in vitro effect of porcine insulin on Na+ + K+, Ca2+- and Mg2+-ATPases of the rat erythrocyte membrane of normal and alloxan-induced diabetic rats was investigated. Na+ + K+- and Ca2+-stimulated enzyme activities were significantly decreased in diabetic rats in comparison to normal animals. The specific activities of both these ATPases in the latter group were markedly reduced on pre-incubating the ghosts with insulin. Similar treatment of the erythrocyte membranes of diabetic animals, however, resulted in a significant increase of these activities. These qualitatively different effects of the hormone in the two groups increased progressively with hormone concentration and duration of pre-incubation. Mg2+-stimulated ATPase activity was not significantly affected in diabetes or by insulin.
Adenosine Triphosphatases↗
Changes in insulin receptor functions of the erythrocyte by treatment of non-insulin-dependent diabetes mellitus (NIDDM) patients with glibenclamide and diet control.
The insulin binding of erythrocytes from: (i) fifteen age-matched normal subjects, (ii) ten untreated NIDDM patients and (iii) fifteen treated (glibenclamide + hypocaloric diet) NIDDM patients (all males) has been studied. A significant decrease in specific insulin binding was observed in group (ii) which improved in cases controlled after treatment (group iii). Scatchard analysis of the results suggested that changes in insulin binding were due to alteration in the number of insulin receptors on erythrocytes. The number of insulin receptors/cell was 471 in normals, 160 in diabetics and 282 in treated diabetic subjects. No significant change in the binding affinity was observed in the three groups (1.0 X 10(8), 1.2 X 10(8) and 1.1 X 10(8) M-1 in normal subjects, untreated diabetics and treated diabetics, respectively).
Adult↗
In vitro insulin effect on acetylcholine esterase of erythrocyte membranes of normal and diabetic rats.
Alloxan induced diabetes in rats was associated with a significant reduction in the acetylcholine esterase activity of the erythrocyte membrane. Preincubation of these membranes with insulin caused a rapid but transient stimulation of this enzyme activity in both normal and diabetic rats, the effect being more marked in the latter group.
Acetylcholinesterase↗
Cardiac arrest: abdominal CT imaging features.
We report computed tomographic findings of two unusual cases of sudden cardiac arrest. The imaging features documented include reflux of contrast into the abdomen as indicated by opacification of renal veins, hepatic veins, inferior vena cava, and hepatic and renal parenchyma. The reflux of contrast into the portal vein in one patient has not been described in the literature. The thoracic findings were reflux of contrast into the coronary sinus, nonopacificaton of the left ventricle with intravenous contrast, and lack of cardiac motion artifact.
Abdomen↗
Secretion of acid phosphatase by axenic Entamoeba histolytica NIH-200 and properties of the extracellular enzyme.
Entamoeba histolytica (NIH-200) secreted large amounts of acid phosphatase in its external environment when grown axenically in modified TPS-II medium. Fractionation by DEAE-cellulose chromatography of the precipitate obtained from the cell-free medium at 60% ammonium sulfate saturation yielded 3 distinct peaks of enzyme activity. The enzyme in all the peaks showed resistance to tartrate but was inhibited by fluoride, cupric chloride, ethylene diamine-tetra acetic acid, ammonium molybdate and cysteine; however, enzyme associated with different peaks differed in its polyacrylamide gel electrophoretic profiles and behavior towards concanavalin A.
Acid Phosphatase↗
Literacy differentials in tribal and non-tribal population of India, 1981.
The author investigates literacy differentials between tribal and non-tribal populations in India, using 1981 census data. "Spatially, the index is high in tradition gripped and economically backward areas of Western Rajasthan, of central highlands and of Western Arunachal Pradesh. It is low in [the] Christian tribal belt of [the] northeast; the early exposed areas of [the] southern peninsula, parts of Gujarat, Maharashtra and Karnataka, and numerically insignificant areas of northern Rajasthan and Western Himalayas."
Asia↗
Male-female literacy differential in India--1981.
The author examines inequalities in the literacy rates between males and females in India. Regional variations in literacy are examined by district using maps. "The male-female literacy differential is low in coastal, peripheral and metropolitan areas and is high in inland and mountainous areas. These regional disparities are the product of differences in length of educational background, age at marriage, level of urbanisation, standard of living and proportion of socially conservative and backward sections of society.... The study in spatial dimension provides a strong base for the removal of sex biased discrimination in society."
Asia↗