Biomedical subjects

P S Scola

Publications and source records attributed to P S Scola.

3 recordsLinked to original sources

PubMed1992

Menstrual cycles and basal body temperature curves in women with Down syndrome.

Menstrual histories were obtained from 51 females with Down syndrome between the ages of 10-27 years. The average age at onset of menstruation of girls in our study was 12 years, 6 months. Seventy-six percent of them had regular menstrual cycles with an average length of menstrual flow of 4 days, and most menstrual cycles lasted 25-30 days. Eight of the women with regular menstrual cycles provided 26 basal body temperature charts. When basal body temperatures were graphed using the smoothed-curve technique, 88.5% had biphasic curves indicative of an ovulatory pattern.

Adolescent↗

PubMed1988

Parents' perception of social and sexual functions in adolescents with Down's syndrome.

The authors investigated parental perceptions of social interactions, interest in the opposite sex, sexual functions and issues concerning sex education in young persons with Down's syndrome. The evaluation of the data revealed that more than half of the study population showed interest in the opposite sex and are attending social gatherings. Many of the youngsters had expressed a desire to get married, however, only a few had an interest in sexual relationships. Masturbation was observed in 40% of the young men and in 22% of the young women. About half of the parents feel that their children should be sterilized or should have other forms of birth control if they would be able to reproduce. Only a limited number of adolescents had sex education. More parents who have girls with Down's syndrome than those who have boys are worried that their child may be taken advantage of sexually.

Adolescent↗

PubMed1987

Partial trisomy 2p.

A 4-year-and-10-month-old girl was referred to the Child Development Center, Rhode Island Hospital, Providence, Rhode Island, USA, for evaluation because of mental retardation. She was found to have short stature, congenital heart disease and dysmorphic facial features. A chromosome analysis revealed an unbalanced translocation with trisomy of the distal part of the short arm of chromosome 2 (2p21----2pter). A balanced reciprocal translocation was identified in the maternal karyotype 46,X,t(X;2)(q28;p21). The phenotype of partial trisomy 2p is discussed.

Child, Preschool↗