Biomedical subjects
P Robertson
Publications and source records attributed to P Robertson.
Operative and assisted delivery.
Decisions about the role of cesarean section, forceps, and vacuum delivery in obstetrics continue to be a challenging part of daily obstetric practice. Five interesting papers on this topic are reviewed, including a comparison of international rates of cesarean sections and vaginal births after cesarean section, the method of choice for the delivery of the low-birth-weight fetus presenting as vertex, the advantages of a prelabor cesarean section for a fetus diagnosed with meningomyelocele, and the appropriate role for the midforceps delivery in the 1990s.
Magnesium and calcium ion binding to bovine prothrombin fragment 1. A circular dichroism, fluorescence, and 43Ca2+ and 25Mg2+ nuclear magnetic resonance study.
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pH dependence of magnesium ion binding to prothrombin fragment 1 and gamma-carboxyglutamic acid-containing peptides via 25Mg NMR.
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Calcium and magnesium binding to gamma-carboxyglutamic acid-containing peptides via metal ion nuclear magnetic resonance.
The determination of binding constants of metal ions to biomolecules is approachable via many techniques. Metal ion NMR spectroscopy is an alternative to more traditional techniques and is complementary to them, particularly in investigations of the interactions of metal ions with relatively small peptides containing multiple ionizing groups. The method requires relatively small amounts of material, is fairly fast, and is carried out at equilibrium. Our study has been of calcium and magnesium ion binding to gamma-carboxyglutamic acid (Gla)-containing peptides. Dissociation constants of approximately 0.6 mM for the binding of either metal ion to Z-D-Gla-D-Gla-OMe have been obtained. The procedure for determination of these constants via metal ion NMR is discussed.
From statistics to action.
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Letter: Viral antibodies in thyrotoxicosis.
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In vitro determination of the antimicrobial properties of two cyanoacrylate preparations.
Isobutyl and trifluoro cyanoacrylates showed varying degrees of inhibition for Lactobacillus casei and Staphylococcus aureus when tested by the spread plate technique. Candida albicans and Pseudomonas aeruginosa were resistant. The results tend to support the view that inhibition of growth was due to the vapor effect and not the diffusibility of the cyanoacrylates.
Sunscreen use and environmental awareness among beach-goers in Cape Town, South Africa.
BACKGROUND: The potential impact on health of increased exposure to sunlight has caused increased concern in recent years. In South Africa little is known of peoples' sunbathing habits, use of sunscreens, and factors influencing these practices. AIMS: The aims of the study were to determine sunscreen usage among the South African beach-going public, to determine sunbathing practices of beach-goers and to determine factors influencing peoples' sunbathing habits. METHODS: Cluster sampling at 3 popular Cape Peninsula beaches was used to select a sample of 231 white adult beach-goers. Questionnaires were administered to obtain information on the use of sunscreens, frequency of use, peoples' sunbathing activities, their susceptibility to sunburn and ability to tan, whether there was a history of severe sunburn, and knowledge and awareness of environmental issues. Information was also obtained on personal characteristics and sociodemographic factors. RESULTS: 50% of respondents were using a sunscreen on the day of the interview. More women than men, and people over 25 years of age relative to younger persons, made frequent use of sunscreen lotions. A sun protection factor (SPF) of 15 or more was being used by 5% of the population. With respect to peoples' knowledge and awareness of the environment, 90% of the population cited skin cancer as a potential consequence of over-exposure to sunlight, although, in general, knowledge of environmental issues was poor. CONCLUSIONS: A major effort is needed to improve attitudes and practices in South Africa with respect to sun-tanning activities.