Biomedical subjects
Publications and source records attributed to P Ranque.
The authors report the distribution and the incidence of dracunculiasis in the seven administrative regions of Mali. They describe the various types of Cyclops habitat and the seasonal variations in transmission. They discuss the resulting effects of dryness and rural water development on this endemic parasitic disease.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
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517 isolations of dermatophytes collected in Mali are reported. The various species are described and the main findings are: --Trichophyton species are more common (85.5% isolated from scalp lesions and 77.5% from skin scrapings) than Microsporum species. --Trichophyton verrucosum and Microsporum canis have been found found for the first time in Mali. --Ill-defined clinical forms of scalp lesions caused by either T. schonleinii or T. soudanense occur in the subsaharian areas of the country.
The authors report the main clues of morbidity, infant mortality, fecundity as well as the main endemic affections detected in the nomadic and seminomadic populations in Gourma that they have noticed during a descriptive epidemiological investigation. The worse clues of general morbidity come from children and among the ethnic groups studied from those of the Tamachèques and the Maures. Malaria, brucellosis, treponematosis (bejel) have a high rate of frequency. The few cases of tuberculosis detected incidentally encourage to search for the real effect of this affection. Urinary schistosomiasis is present in Gossi where durable ponds exist. Intestinal helminthiasis, tineas, and hemoglobinopathies seem not to be problems of public health in the area. Pterygiums and conjunctivitis are frequent while trachoma is absent in Gourma.
The authors set out the methodology and the practical way used in transverse epidemiological investigation with a descriptive aim which was made in natural area: Gourma-Mali. This part of the Sahel, hard to reach, is placed deep in the bend of the Niger river. The population is estimated at 100.000. The weather, ecological and human conditions have been unsettled by the drought. Sometimes, it was difficult to collect the data among the nomadic and seminomadic populations (Tamachèques, Peuls, Maures, Bellahs, Sonraïs). This investigation shows well the practical problems that this kind of study sets out in difficult bioclimatological and ethnological conditions.
The authors draw up "paludometric indications" by studying 938 children and youths, in the Kadiolo area, a humid savanna in the south of Mali, by the end of the dry season (beginning of March). These results give a global indication of 70.6% (cases of malaria) with 94.4% of P. falciparum and 9.96% cases of gametocytic indications. The numbers obtained far from the rainy season let us think that the annual transmission of malaria is continuous with a recrudescence in the humid season explaining largely the infantile mortality. The use of Nivaquine may easily protect these populations from the risk of malaria disease.
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In the village population of Mali situated in the sudan savanna, malariometric indices and hematocrit values were performed before and after mass drug administration given every 15 days by a nurse to three-quarters of the population, with the remaining quarter receiving a placebo. In this population, endemic malaria was stable and high, essentially caused by Plasmodium falciparum. The "protected" population showed a decrease of parasite rate and spleen rate with concomitent rise in hematocrit values. Following the rainy season, when transmission of malaria is highest, the normally observed increase in malariometric indices with lowered hematocrit values were not seen during chemoprophylaxis. While splenomegaly found in rural children is related to malaria, the main etiology of anaemia observed in this age group is probably malaria but a role is played by others factors.