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Biomedical subjects

P R Sisson

Publications and source records attributed to P R Sisson.

66 records · Page 4Linked to original sources
PubMed1979

The use of spore strips for monitoring the sterilization of bottled fluids.

A bacterial spore test has been developed which enables the efficacy of the sterilizing cycle recommended by the British Pharmaceutical Codex (1973) for bottled fluids to be accurately monitored. During a 14-month period this test detected faults in 3.3% of the sterilizing cycles, representing five distinct episodes of sterilization failure that passed unnoticed by the conventional controls of physical measurements and sterility testing. There were no failures of sterilization as detected by conventional techniques which were not indicated by the spore test.

Geobacillus stearothermophilus↗
PubMed1978

A study of carbon dioxide-dependent strains of Streptococcus milleri.

Forty-four strains of non-haemolytic streptococci, from a variety of sites, that required CO2 for aerobic growth were identified as Streptococcus milleri. Of these strains, 40 (90%) possessed the Lancefield group-F antigen, the remainder being non-groupable with antisera to the group antigens A, C, F and G.

Aerobiosis↗
PubMed1977

Inhibition of phagocytosis in vitro by obligate anaerobes.

A variety of species of obligate anaerobes have been shown to interfere with the phagocytosis and killing of Proteus mirabilis and other aerobic bacteria in vitro. Although all the obligate anaerobes examined showed this activity, the effect was greatest with strains of Bacteroides melaninogenicus and B. fragilis. In contrast, none of the 36 aerobes tested acted in this way. These observations suggest that the presence of obligate anaerobes may be fundamental to the pathogenesis of some types of infections.

Bacteroides↗
PubMed1977

The API ZYM system in the identification of Gram-negative anaerobes.

The API ZYM reactions of type species of Gram-negative anaerobes representative of those encountered in human infections and of 56 clinical isolates of such organisms, identified by conventional techniques, were investigated. The API ZYM test clearly distinguished between the different genera and species examined and appears to provide a simple, reliable method for the identification of this group of organisms.

Bacteriological Techniques↗
PubMedDate not supplied

Microbial synergy.

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Bacteria↗
PubMedDate not supplied

Microbial synergy.

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Bacteroides fragilis↗
PubMedDate not supplied

Characterization of Aspergillus isolates by pyrolysis mass spectrometry.

Pyrolysis mass spectrometry (PYMS) is a useful typing method for many bacterial and Candida species. We attempted to type Aspergillus spp. by PYMS. Four distinct A. fumigatus isolates could not be distinguished from each other, whereas one A. niger and one A. terreus could. Poor reproducibility was shown using multiple identical cultures of a single A. fumigatus isolate and several isolates of the same DNA type. PYMS is obviously an unsuitable typing method for Aspergillus spp.

Aspergillosis↗