Search PubMed⌕ Search

Biomedical subjects

P R Pavan

Publications and source records attributed to P R Pavan.

34 records · Page 2Linked to original sources
PubMed1987

Exogenous bacterial endophthalmitis treated without systemic antibiotics.

We treated 16 patients (16 eyes) with culture-proven exogenous bacterial endophthalmitis with intravitreal and subconjunctival antibiotics but without systemic antibiotics. After one to two sets of intravitreal injections, intraocular inflammation abated in all patients. After further surgery in four patients, all 16 eyes had clear media and attached retinas. Fifteen eyes attained a visual acuity of 20/400 or better; 12 eyes achieved 20/80 or better.

Adolescent↗
PubMed1987

Bilateral melanocytic uveal tumors associated with systemic non-ocular malignancy. Malignant melanomas or benign paraneoplastic syndrome?

A 90-year-old woman developed bilateral diffuse melanocytic tumors of the uveal tract nearly 1 year before she died from an occult ovarian carcinoma. Although the syndrome of bilateral diffuse melanocytic tumors of the uvea and systemic carcinoma has been described, the uveal tumors in this patient were different in that they were indistinguishable histologically from mixed cell-type malignant melanoma. Although the relationship between the systemic malignancy and the uveal tumors is unclear, the cytologic features of the uveal tumors in this syndrome are probably more variable than originally thought.

Aged↗
PubMed1987

'Blow-outs' in the retinal pigment epithelium.

A hole was detected in the epithelium of a retinal pigment epithelium (RPE) detachment in two patients. Leakage through the hole led to an elevation of the overlying neurosensory retina in each case. The resulting vision was 20/70 in one eye and 20/30 in the other. The defects in the RPE occurred in a setting different from that usually seen with tears in the pigment epithelium and had a different clinical appearance.

Adult↗
PubMed1984

Retinal fold in macula following intraocular gas. An avoidable complication of retinal detachment surgery.

Liquid vitreous was replaced with air during a scleral buckle for a superotemporal retinal detachment. After surgery, the patient was positioned so that air rolled over the detached retina from anterior to posterior, pressing a fishmouthed tear against the buckle that resulted in reattachment. After the air was absorbed, a large retinal fold was seen in the superotemporal macula along the former posterior margin of the detachment. If the patient had been positioned so that air rolled over the detached retina from posterior to anterior, the potentially visually destructive posterior retinal fold could have been avoided.

Absorption↗
PubMed1984

Diabetic vitrectomy.

Diabetic vitrectomy is usually performed to remove vitreous blood or to relieve traction of the macula. In addition to removing vitreous opacities and severing all anteroposterior connections of the posterior hyaloid face with a cutting and sucking probe, tangential traction in and around the macula is eliminated by sectioning preretinal membranes with intraocular scissors. Complications are significant in terms of both their incidence and their consequences. They include choroidal or subretinal infusion, peripheral and posterior retinal breaks, intraoperative bleeding, and neovascular glaucoma. Proper management can minimize the occurrence and adverse effects of these complications. If prognostic factors are favorable, visual improvement occurs in 78 to 59% of eyes postoperatively. Preoperative iris neovascularization, florid proliferative diabetic retinopathy, long-standing detachment of the macula, and iatrogenic retinal breaks are all correlated with significantly lower success rates. Three independent studies have shown that if visual improvement is present 6 months postoperatively, the results are usually long-standing [2, 8, 20].

Cataract↗
PubMed1984

Optic disc edema.

Explore the source record for details and available documents.

Adolescent↗
PubMed1983

Diabetic rubeosis and panretinal photocoagulation.

Iris fluorescein angiography was used to perform the first prospective, controlled, masked evaluation of the effect of panretinal photocoagulation on diabetic rubeosis. Eyes with rubeosis had iris fluorescein angiograms five to seven weeks apart. Eyes either had laser treatment immediately after the first angiogram or had no laser treatment between angiograms. The rubeosis was said to have improved if all three masked readers independently selected the angiogram performed last as having the less severe rubeosis. In eyes with severe rubeosis, only two of 11 (18%) spontaneously improved whereas 11 of 15 (73%) improved following laser therapy. In eyes with mild rubeosis, one of ten improved spontaneously and one of ten improved following laser therapy. Iris fluorescein angiography documented regression of severe but not mild rubeosis following panretinal photocoagulation.

Clinical Trials as Topic↗
PubMed1981

Acute pressure elevation following panretinal photocoagulation.

Intraocular pressure increased in 17 of 18 eyes treated for diabetic retinopathy with argon laser panretinal photocoagulation. All eyes had open anterior chamber angles before treatment. Fifteen eyes, continued to have open angles when first examined after treatment. The pressure elevation in these eyes averaged about 10 mm Hg, was detected soon after laser treatment, and persisted for several hours. Outflow facility usually was reduced. Three eyes had closed angles and elevated pressures when first examined after treatment. I addition, in five eyes that initially had open angles, angle closure developed later. Thus, the pressure elevation after extensive retinal photocoagulation usually begins with an open angle mechanism, but later may be due to angle closure as well. The reason for the pressure rise with an open angle is unknown.

Adult↗
PubMed1980

Optic disc edema in juvenile-onset diabetes.

The clinical and photographic records of patients with juvenile-onset diabetes and nonneurologic disc edema were reviewed to determine the natural history of the disease. Six female and two male patients, 14 to 40 years old, who had had diabetes for seven to 22 years had no visual complaints or mild blurring. All had 6/9 or better visual acuity and normal blood pressure. Visual fields were normal or showed an enlarged blind spot. The edematous discs had superficial, dilated, radially oriented, fluorescein-incontinent capillaries. Two patients had simultaneous neovascularization of the disc. Three received laser photocoagulation, and five received no therapy. In the seven followed up for six months or more, the edema resolved, resulting in 6/6 visual acuity. These findings suggest the edema resulted from a reversible vasculopathy that, due to few symptoms, may be more common than is presently appreciated.

Adolescent↗
PubMed1977

The elimination of herpes simplex plaques by antibody and the emergence of resistant strains.

Established type 1 HSV plaques were eliminated by antibody. Antibody had to remain in contact with infected cells for several days to have a maxi;mum effect. It did not prevent the production of viral induced antigens in a cell when applied after the cell was infected but did prevent the transmission of infection to contiguous cells. Strains which were resistant to elimination by antibody formed syncytia, did not grow to significantly higher titers than nonresistant strains, and were as easily neutralized by antiserum as nonresistant strains.

Antibodies, Viral↗
PubMedDate not supplied

Retinal infiltrates in six patients with an associated viral syndrome.

This report documents the fundus findings in ten eyes of six patients who had retinal infiltrates develop during or shortly after a viral-like illness. The whitish infiltrates varied in size from 150 to 1700 micron. They occurred in both the posterior pole and periphery, and were located in the superficial as well as deep retinal layers. There was minimal or no vitritis. The infiltrates resolved over a period of months with and without chorioretinal scarring. The optic nerve was involved in two patients, causing a temporary decrease in acuity. However, the only eye left with visual acuity less than 20/40 had a paracentral macular lesion that scarred.

Adolescent↗