6-thiopurines as substrates and inhibitors of purine oxidases: a pathway for conversion of azathioprine into 6-thiouric acid without release of 6-mercaptopurine.
Explore the source record for details and available documents.
Alkanes↗
Biomedical subjects
P R Knight
Publications and source records attributed to P R Knight.
The effect of antilymphocyte serum (ALS) on the secondary immune response in mice.
Explore the source record for details and available documents.
Animals↗
The effect of skin allografts on the reticuloendothelial system.
Explore the source record for details and available documents.
Animals↗
The effect of antilymphocytic serum (ALS) on the reticuloendothelial system (RES) of mice.
Explore the source record for details and available documents.
Animals↗
Psychological aspects of the management of chronic renal failure.
Explore the source record for details and available documents.
Countertransference↗
Equine cystitis and ataxia associated with grazing of pastures dominated by sorghum species.
Explore the source record for details and available documents.
Animals↗
Conversion of azathioprine into mercaptopurine and mercaptoimidazole derivatives in vitro and during immunosuppressive therapy.
Explore the source record for details and available documents.
Adult↗
The psychiatric contribution to a renal unit undertaking chronic haemodialysis and renal homotransplantation.
Explore the source record for details and available documents.
Adaptation, Psychological↗
Psychological screening of potential donors in a renal homotransplantation programme.
Explore the source record for details and available documents.
Adult↗
What is the relationship between paresthesia and nerve stimulation for axillary brachial plexus block?
BACKGROUND AND OBJECTIVES: To quantify the motor threshold current of a needle following elicitation of paresthesia during axillary brachial plexus block (ABPB). METHODS: This is a prospective, observational study of ABPB in 72 patients. Having elicited paresthesia, the minimum current required to produce a motor response was noted. The development and success of the block were subsequently followed. RESULTS: Nineteen blocks were excluded (18 because of arterial puncture and 1 blocked needle). Of the remaining 53 blocks, 41 (77%) produced a motor response at 0.5 mA or less. The median current was 0.17 mA (range, 0.03 to 3.3 mA). The site of initial paresthesia and subsequent motor response were related in 43 (81%) of cases. CONCLUSIONS: A needle position causing paresthesia produced a motor response at 0.5 mA or less in 77% of cases studied. This current may, therefore, be a reasonable threshold to aim for when performing an ABPB.
Anesthetics, Local↗