Comparison of computer models of the human arterial system for the assessment of clinical data.
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Biomedical subjects
Publications and source records attributed to P R Bourne.
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A cardiac monitoring system has been developed that incorporated phasic aortic blood flow measurement by an extractable electromagnetic flow probe and high-fidelity arterial blood pressure recordings. Cardiac output, stroke volume, and peak aortic blood flow are measured continuously; using logarithmic amplifiers, the pressure-flow derivatives of left ventricular function, such as cardiac power and stroke work, are obtained beat by beat. This monitor is used to follow the postoperative course of patients undergoing cardiac operations and to evaluate the hemodynamic effect of therapeutic agents.
Continuous measurements on patients after cardiac surgery are usually limited to blood pressure and ECG. This article describes a new monitor which combines instantaneous arotic flow and arterial pressure measurements to derive stroke volume, ventricular power, stroke work, and an indication of left ventricular afterload. The methods used to obtain the new derivatives are discussed and clinical applications described.
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