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P Priollet

Publications and source records attributed to P Priollet.

122 records · Page 7Linked to original sources
PubMed1983

[Morphological abnormalities of nailbed capillaries in connective tissue diseases].

The Capillaroscopy Unit of Broussais Hospital has carried out more than 6,000 examinations involving all areas of pathology and more particularly the special role which the method plays in connective tissue diseases. This experience was used to attempt to define the characteristics of the morphological abnormalities of the nailbed capillaries in connective tissue diseases in the adult. The study was deliberately limited to abnormalities of the capillaries themselves, with the exclusion of abnormalities of the pericapillary spaces, abnormalities of blood flow and abnormalities capable of manifesting themselves in the cold; though bearing in mind that the interpretation of a capillaroscopic examination can be perfectly credible only if all such anomalies are taken into consideration. The following capillaroscopic appearances have been included under the heading "morphological abnormalities": dystrophies, dilatations of the loops without megacapillaries, megacapillaries, telangiectasia, filiform loops, regressive capillaries, long loops and microaneurysms. Groups of these morphological abnormalities form more or less typical associations in connective tissue diseases.

Adult↗
PubMed1983

[Indications for and medical treatment modalities in the thoracic outlet syndrome].

The thoracic outlet syndromes comprise a group of diseases with varied manifestations: nervous, venous or arterial. The definitive diagnosis is difficult and the clinical picture is more important than complementary examinations. There are very precise indications for the various modalities of medical and surgical treatment.

Angiography↗
PubMed1983

[Charcot's blue edema, a case].

The case of an 18 year old Algerian girl with acrocyanosis of the four extremities since childhood and presenting a with 6 months history of oedema of the left hand resulting in severe functional handicap, is reported. Clinically, the oedema suggested a lymphatic origin. However, its localised, strictly unilateral distribution, the normality of vascular investigations, the absence of pain and regression of the oedema during the period of hospitalisation suggested autoaggression. The discovery of tourniquet marks on the skin of the thigh confirmed the diagnosis of Charcot's blue oedema. The patient has a hysterical personality, was of higher than normal intelligence but immature, and could only express herself through her functional handicap, a cry for affection in a rigid family environment only concerned by her scholastic achievements. To our knowledge, there have been 27 other reports of this condition since Charcot's first description in 1890. The majority concerned young intelligent women. Diagnosis is difficult and can only be confirmed by the finding of tourniquet marks on the skin. Psychotherapy is often useful as an underlying neurotic or psychotic personality is commonly found.

Adolescent↗
PubMedDate not supplied

The wall to lumen ratio of the radial artery in patients with Raynaud's phenomenon.

The pathophysiology of Raynaud's phenomenon (RP) remains an enigma. Whatever theories proposed, the final event leading to the clinical symptoms is the occlusion of digital vessels. However, the possibility that the upstream large arterial vessels contribute to vasopasm has never been investigated. We used a high resolution echo-tracking device to calculate lumen diameter, wall thickness, and circumferential wall stress upstream the digital arteries, i.e. at the site of the radial artery. Fifteen control women, 15 age-matched women with primary RP (PRP) and 15 women presenting with a secondary RP due to systemic sclerosis (SSc) were included in the study. All vasodilating agents were discontinued 72 h before the study session, which was conducted in a room with a stable ambient temperature of 22 degrees C. Radial artery internal diameter, intima-media wall thickness, and mean arterial pressure were measured simultaneously. Internal diameter of patients with RP was significantly decreased (p < 0.001 vs. controls) whereas intima-media wall thickness and mean arterial pressure were closely similar in the three groups, resulting in an increase in the wall to lumen ratio. Thus, circumferential wall stress was significantly smaller (p < 0.05 vs. controls) in patients with RP. In conclusion, this study demonstrates that in patients with RP, wall to lumen ratio is increased and circumferential wall stress is reduced at the level of the radial artery. It is suggested that the geometrical and mechanical changes of this artery may favor the downstream occlusive phenomena observed in patients with PRP and SSc.

Adult↗
PubMedDate not supplied

[Early detection of limited joint mobility in diabetic children and adolescents].

Limited joint mobility (LJM) is a common complication of juvenile diabetes, usually assessed by a clinical method, the prayer test. Recently, the interest of the use of a goniometer in measuring subclinical joint limitation has been shown in adult diabetic patients. Joint mobility has been systematically assessed with a goniometer in 58 consecutive diabetic children (mean age = 12.8 yrs, mean duration of diabetes = 3.6 yrs) and compared to 119 normal children, for elbows, wrists, metocarpophalangeal (MCP), proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints of the 5th finger, in order to detect subclinical anomalies. The results showed a significant loss of the MCP flexion and extension, of the PIP flexion and of the DIP extension in diabetic children when the values were analysed according to the physiological variation with age. The prayer test detected LJM in three patients only. The degrees of elbow and DIP extension, and wrist flexion, decrease when the duration of diabetes increases, independently of the age. Anomalies of the 5th finger joint mobility were found to be correlated with microvascular anomalies of retinal angiography and nailfold capillaroscopy. However, no correlation was found with the measure of HbA1c performed at the time of the joint assessment. The measure of joint mobility with a goniometer has detected a decrease of finger mobility in diabetic children, early in the course of diabetes. These preliminary data should be confirmed in a longitudinal study that will be performed in a larger setting, in order to propose diagnostic criteria of infraclinical diagnosis of LJM.

Adolescent↗
PubMedDate not supplied

Detection by nailfold capillary microscopy of early morphologic capillary changes in children with insulin dependent diabetes mellitus.

Nailfold capillary microscopy (NCM) is a non invasive method to investigate digital microcirculation. The NCM pattern of 70 children with diabetes (duration varying from less than one month to 18 years) and of 35 healthy children was studied. Several capillary loops anomalies were observed: haemorrhages, disorganisation, dystrophies, microaneurysms. The anomalies were more frequent in children with diabetes (61.4%) than in the controls (20%; p less than 0.001). Haemorrhages and nailbed disorganisation were seen in both groups. Dystrophies were found more frequently in the diabetic group (46%) than in the controls (17%; p less than 0.01). Microaneurysms were observed only in diabetic children (27%; p less than 0.001); they were present in 18.5% of the children with a diabetes duration of less than 2 years and their frequency did not increase with the duration of the disease. Sex ratio, age and HbA1c were not different between the diabetic children with or without microaneurysms. No relationship was found between retinal angiography and NCM detection of the microaneurysms. In conclusion, NCM is able to detect frequent anomalies of the digital microcirculation, especially microaneurysms, early in the course of diabetes in children. The follow up of this pediatric population will provide further information on the prognostic value of these lesions.

Adolescent↗
PubMedDate not supplied

Nailfold capillary microscopy: a new technique for finger systolic pressure measurement.

To assess the value of nailfold capillary microscopy (N.C.M.) for measuring finger systolic pressure (F.S.P.), 25 patients were studied by N.C.M. and plethysmography. Twelve of them presented Raynaud's phenomenon. The results revealed that N.C.M. can be correlated with plethysmography for measuring F.S.P. Therefore, N.C.M. with F.S.P. measurement is a practical, inexpensive method, and provides an additional microvascular diagnostic evaluation.

Adult↗