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Biomedical subjects

P Pochop

Publications and source records attributed to P Pochop.

8 recordsLinked to original sources

[Retinopathy as a complication of Waldenstrom's disease].

The authors wish to demonstrate on the case of a 52-year-old female patient who suffered from non-specific symptoms and impaired visual functions, typical changes on the fundus which may be due to some serious haematological diseases. In the case of the mentioned patient the haematological disease (Waldenström's disease) was manifested by hyperviscous and anaemic syndrome. The ophthalmological finding in the general picture was not dominant but on the whole typical and contributed to a more rapid diagnosis of the fundamental disease. Changes on the fundus by which the hyperviscous syndrome is manifested must be known and in the differential diagnosis the possibility of haematological disease should be taken into account as in the majority patients are involved who are at risk of sudden loss of eyesight and sudden death.

Diagnosis, Differential↗

[Transcleral laser photocoagulation and cryocoagulation of the retina in children with retinopathy of prematurity].

The objective of the work was to compare the effectiveness of transscleral laser photocoagulation and cryocoagulation of the retina in the treatment of retinopathy of premature infants (ROP). During the period from March 1999 to April 2001 at the Ophthalmological Clinic for children and adults in the Motol Faculty Hospital 80 eyes of 40 children with the borderline stage of ROP were treated. In 40 eyes cryocoagulation was performed, in 40 transcleral photocoagulation of the retina. The mean gestation age of the infants on delivery was 28.7 weeks, the postconception age at the time of operation 36.7 weeks. The follow up period varied from 1 to 24 months. All therapeutic provisions were made with premedication and under local anaesthesia. For a stabilized finding without progression we took an adherent retina without subsequent traction changes. Cryocoagulation was successful in 87.5%, laser photocoagulation in 85%. Both methods proved equally effective. In photocoagulation the authors recorded a lower incidence of local complications. General undesirable effects were not recorded in any of the treated children. Transscleral photocoagulation extends contemporary therapeutic possibilities in patients with ROP.

Cryosurgery↗

[Surgical treatment of sequelae of oncologic treatment in the orbital region].

Complications after surgical oncological treatment and irradiation such as impaired growth of the facial skeleton, orbitoethmoid fistulae and others are an important problem for the patient's further fate. For their elimination collaboration of the ophthalmologist and maxillofacial or plastic surgeon is essential as various reconstruction procedures must be used some of which are mentioned in the paper. Some procedures are demonstrated on three patients where osteotomies of the orbit and implantations of bone grafts were performed as well as transplantation of vascularized tissues and skin flaps. In all mentioned patients marked improvement was recorded.

Adolescent↗

[Use of computer tomography for localization of a biopsy needle for tissue collection from the orbit].

In four patients with orbital expansion the authors used computed tomography (CT) to locate the bioptic needle inserted into the orbit. In all these instances it proved possible to collect a sufficient amount of pathological tissue to assess the diagnosis. Serious side-effects were observed only in one case, where the patient developed after insertion of the needle transient bradycardia. CT was also used to locate the needle for exhausting of blood from a lymphangioma of the orbit.

Biopsy, Needle↗

[2 years' experience with treatment of uveal melanoma using the Leksell gamma knife].

In the last years, the therapy of ocular melanoma with Leksell's gamma-knife was indicated at several clinics in Prague. It referred to bulky tumors and to unfavourably localized tumors so that only enucleation of the eyeball was the only alternative in our conditions. The results of the treatment of 11 patients have been evaluated in this article. Some other patients treated with this method have not been included in this sample for various reasons (short-term follow-up, combination of radiotherapy with gamma-knife with other therapeutic modality etc.) Gradual decrease in tumor size developed in 10 patients during follow-up. The decrease in tumor size has been observed on repeated ultrasound examinations and magnetic resonance imaging. The growth of tumor was reappeared in one patient, which led to the necessity of enucleation of the eyeball. The complications in other patients were numerous but not serious to such extent that would lead to enucleation. Marked deterioration in visual acuity connected with the treatment occurred in 6 patients. The results achieved by this method are comparable with those achieved by other therapeutic modalities and with the results from other clinics employing gamma-knife for the treatment of uveal melanoma. The results lead to the conclusion that this is an effective method of treatment of uveal melanoma and that this method is able to go through further development, especially in combination with other therapeutic modalities.

Adult↗

[Personal experience with treatment of vascular diseases using the Leksell gamma knife].

The application of radiosurgical treatment in ophthalmology is a new and not quite common procedure. The existence of 80 departments in the world with more than 15,000 treated patients suggests however that the therapeutic method is being extended and that its application in ophthalmology will be more extensive in future. The most numerous indication groups for treatment with a Leksell gamma-knife(LGK) worldwide are vascular malformations (44%), benign tumours (33%) and malignant tumours (22%). Other groups include among others functional disorders and metastatic processes (15).

Adolescent↗

[Masquerading syndromes].

Masquerade syndromes comprise a number of diseases imitating as to their clinical picture inflammation of the eye. These diseases comprise also malignant tumours. The authors present three patients where intraocular tumours (lymphoma, leukaemia, melanoma of the choroid) reminded of chronic uveitis.

Aged↗

[Giant-cell temporal arteritis--indications for biopsy].

The authors summarize the knowledge of diagnostics of giant cell arteritis and attempt to determine the criteria for indication of temporal artery biopsy. The difficulties of diagnostics are documented by case-report of 75-year-old patient in whom considerably varied complex of symptoms of temporal arteritis combined with development of polymyalgia rheumatica has developed.

Aged↗