[Etiologic problems posed by a catatonic syndrome].
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Biomedical subjects
Publications and source records attributed to P Pichot.
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The present study investigates the psychometric adequacy of a self-report inventory of depression (the QD2) with respect to the severity of depressive symptoms, within the framework of a unidimensional model of depressive states. Responses to the 52 QD2 items, by 481 subjects divided into four groups (depressed, psychiatric, somatic and control), were subjected to a Rasch analysis. Results show that 15 items (QSD(R1] display a satisfactory goodness of fit for both items and persons, as defined by the Rasch model. This set of items, solely related to 'pure' depression, gives a measure of the severity of depression, free from anxiety symptoms. The discussion focuses upon the advantages of the Rasch model as compared to traditional tests. The Rasch 15-item solution should provide a parsimonious tool for future studies on the classification of depressive disorders.
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The author discusses the successive modifications of the concept of mental disease. Initially syndromic, it has tended, since Bayle, to become clinico-etiological. The introduction of evolution as a criterion is responsible for the "Krankheitsbegriff" of Kraepelin. The initially categorical nature of the model has met with difficulties when personality disorders has been considered as belonging to psychiatry. Kurt Schneider has tried to solve the problem thus posed. Although it is avoided by the modern nosological systems, the choice between the categorical and the dimensional models is a prerequisite for a clear definition of mental disease.
The provisional definitions presented in this report are the first step of an empirical investigation initiated to establish operational definitions for schizophrenia and other non-affective psychoses of classical French nosology. They are the result of French clinicians' agreement on the identification of particular syndromes as distinct mental disorders.
The present report presents the final results of an empirical investigation initiated to establish operational definitions for schizophrenia and other non-affective psychoses of classical French nosology. For each category, the authors provide diagnostic criteria and algorithms. In addition, they propose a decision tree for the differential diagnosis of psychotic features included in the French classification of mental disorders.
Fifty-four depressed patients aged 18 to 65 years were treated for 4 weeks with a daily dose of either 60 mg mianserin or 150 mg imipramine in a double-blind controlled trial. The results which were measured on the Hamilton rating scale, on the Beck and on the Overall rating scale, on the brief psychiatric rating scale (BPRS) and on a global rating scale, did not show any significant difference relative to the antidepressive efficiency of both products. The frequency of side-effects however was significantly lower in the mianserin group than in the imipramine group.
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