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Biomedical subjects

P Peltokallio

Publications and source records attributed to P Peltokallio.

At least 37 records · Page 2Linked to original sources
PubMed1978

Capillary permeability and maximal blood flow in skeletal muscle in athletes and non-athletes measured by local clearances of 133Xe and 131I-.

The effect of heavy endurance training on capillary diffusion capacity (CDC) and maximal blood flow (MBF) in skeletal muscle was studied in eleven highly-trained athletes and ten sedentary adult volunteers. MBF was estimated from 133Xe clearance and CDCI from 133Xe and 131I- clearances in the anterior tibial muscle after ischaemic exercise. The athletes had a significantly greater MBF, 131I- clearance and CDCI than the control subjects (P less than 0.001). The average increment of MBF was 37% and that of CDCI 48%. Increase in CDC is considered to reflect an increase in capillary surface area due to physical training.

Adult↗
PubMed1977

Solitary diverticulum of the caecum and its complications.

Solitary diverticulum of the caecum is very rare and assumes clinical interest only when inflamed. Preoperatively the condition is virtually impossible to distinguish from acute appendicitis, and even during operation its differentiation from carcinoma is difficult. It is also important to determine whether or not an underlying solitary diverticulum of the caecum is present. In the present series the symptoms and clinical examination as well as laboratory findings pointed to acute appendicitis, which was in fact the preoperative diagnosis in all our patients. In one case the operative findings were strongly suggestive of carcinoma, which was only excluded by inspection and histological examination of the specimen. The wall of the diverticulum was necrotic in all cases. It had already perforated in the previously mentioned case, and right hemicolectomy was performed. An inflamed, but recognizable, solitary diverticulum of the caecum was treated by excision, but the tumour-like mass produced by the diverticulum was removed by resection. In view of the considerable possibility of underlying carcinoma, the authors support an aggressive trend in the treatment of "inflammatory tumours" of the caecal wall.

Adult↗
PubMed1975

The significance of thermography in the diagnosis of acute abdominal disease.

Thermography appears to be a useful supporting aid to classical methods of examination in the clarification of the problems of acute abdominal disease. In a study of 100 patients thermography was in support of the true diagnosis in acute appendicitis in 63 per cent, in acute biliary tract disease in 59 per cent, and, in an attempt to differentiate between tumor and periappendicular abscess, assistance was rendered by thermography in 53 per cent of patients. However, some uncertainty exists because carcinoma often produces in its environment an inflammatory reaction, which causes an increase of temperature visible in the thermogram. In the present series thermography produced a finding supporting the correct diagnosis in 59 per cent. Errors occurred most often in obese patients, who have thick abdominal covers. Thermography also has an obvious application in the localizing of postoperative suppurative foci.

Abdomen, Acute↗
PubMed1975

Yeast bezoar formation following gastric surgery.

Yeast bezoar seems to be a relatively common late complication after various gastric operations. The incidence of bezoar depends decisively on the nature of the operation. Vagotomy in particular is conducive to the formation of a bezoar. Vagotomy + Billroth I resection proveded the most propitious conditions for the growth of yeast, for every one-half of the patients in this group developed a bezoar. Yeast bezoars usually appear within a year of the operation. The majority disappear during the first follow-up year, many without any therapy. However, in some cases the bezoar was a rather inconvenient late complication of gastric surgery and one that gave symptoms. It is difficult to draw any definite conclusions concerning the effect of therapy on the disappearance of the bezoar. We used gastric lavage and antimycotics as well as substances that increase gastric acidity. There is still no known method of preventing the formation of yeast bezoars. In the present consensus, a change in the acid conditions and disturbed gastric motility postoperatively are conducive to the formation of a bezoar.

Adult↗
PubMed1975

Vascular pattern in ileal Crohn's disease.

Angio-, histo- and microangiographic studies were performed on five operative specimens of chronic regional enteritis affecting the ileum. In every patient the vascular pattern differed greatly from that seen in normal ileum and the changes were similar in each investigation. The number of long vasa recta and short vasa recta were increased, but the hypereaemic reaction was limited to the submucosa and mucosa. The long vasa recta arising from the marginal artery arcades were three to five times as close together in the affected regions as normally but their calibre was smaller than normal. The vessels were evenly spaced and ran without variation in their calibre up to the antimesenteric border of the gut. The thicker the mesentery, the wider the angle where the long vasa recta divided to form an anterior and a posterior branch. When the wrapping phenomen occurred this angle exceeded 90 degrees. The short vasa recta branching from the long vasa recta formed a very thin vascular network and thus the affected part of the gut could be easily distinguished from the normal ileum. The vascular changes were limited to the regions that were macroscopically abnormal. The arteries were well organized, but in the most severe cases where the architecture of the gut was destroyed the vascular pattern was also confused. The vascular pattern differed from that seen in malignant disease in two respects: there were no clear changes in the vascular calibres even in the most severe cases and no evidence of open arteriovenous shunts. The vascular changes were regarded as secondary to the fibrotic reaction in chronic regional enteritis and accurately reflected the severity of this reaction.

Adult↗