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Biomedical subjects

P Patka

Publications and source records attributed to P Patka.

82 records · Page 5Linked to original sources
PubMed1985

Surgical treatment of pathological fractures caused by bone metastases.

A survey of the surgical treatment of 31 patients with metastases in the long bones is presented. Early diagnosis is essential to prevent pathological fractures in patients with a malignancy. Localized bone pain and an abnormal isotope bone scan or X-ray are the most reliable clues to diagnosis. Should a pathological fracture occur, reduction and internal fixation are indicated to keep the patient active and reduce pain. This was performed in 29 of the cases reported here. Fixation prior to fracture was carried out in six patients. The advantage of this strategy is that it reduces both operative risks and duration of hospitalization. Furthermore, it creates a more favourable situation with regard to preoperative diagnostic appraisal and choice of approach to improve the mechanical qualities of the bone involved, thus preserving function and activity.

Adolescent↗
PubMedDate not supplied

A retrospective analysis of the intubations performed during 5 years of helicopter emergency medical service in Amsterdam.

INTRODUCTION: Different skilled personnel perform prehospital airway management, by far one of the most challenging skills with major consequences upon failure. SETTING: The setting for this study was the helicopter emergency medical service at the Vrije Universiteit Medical Center, Amsterdam, the Netherlands. METHODS: We conducted a retrospective analysis of all medical charts of intubated trauma patients in the period from May 1995 to May 2000. We focused on intubation reasons and conditions. RESULTS: In 43 of 653 patients (7%) the process of intubation was recorded as being difficult, leading to 5 failed intubations (11.6%). In 432 of 653 trauma victims (66%), general anaesthesia was required before intubation. Forty (9%) of these patients died, most soon after arrival in the hospital. The clinical condition of 221 (34%) patients was so poor that they did not require additional drugs for intubation; 73% of those patients died, with two-thirds dying at the accident site. CONCLUSION: The rate of difficult intubation in this analysis is low (7%). The overall airway failure (11.6%) is the same as seen in the literature when sedation and relaxation are used. An adult trauma victim with a Revised Trauma Score of 0 has a very poor prognosis of survival.

Air Ambulances↗
PubMedDate not supplied

A new model for posttraumatic osteomyelitis in rabbits.

A new animal model for posttraumatic osteomyelitis was designed. This model mimics the pathogenesis of the human disease more accurately than models presently available. Femora of New Zealand white rabbits were exposed at the greater trochanter and a stainless steel rod was inserted into the marrow cavity. A Staphylococcus aureus suspension was placed in and around a bone defect, which was drilled midshaft. The disease was evaluated by clinical observation and roentgenographic, hematologic, bacteriologic, and histologic parameters. Osteomyelitis developed in all 24 infected rabbits. None of the five rabbits receiving only an intramedullary rod developed an osteomyelitis. This model proves that an experimental posttraumatic osteomyelitis associated with a foreign body can be reliably induced, even when no infection-promoting chemical agents, small inoculum of bacteria, or minimal bone trauma is present.

Animals↗
PubMedDate not supplied

Tracheal reconstruction with hydroxyapatite tracheal prosthesis.

A porous hydroxyapatite tracheal prosthesis was implanted in rabbits after resection of a 15 mm circular segment of the cervical trachea. Postoperatively the animals were followed by radiography, bronchoscopy, and microscopy at the time of autopsy. The longest survival time was 22 weeks. All the rabbits died of infection at the prosthetic site or of progressive stenosis at the anastomoses. The prosthesis was incorporated by surrounding tissues, but no overgrowth of ciliated epithelium on the luminal surface of the prosthesis was observed. Although a hydroxyapatite tracheal prosthesis is tolerated in rabbits, covering of the luminal surface of the prosthesis with a non-porous layer to prevent infection and to permit mucosal overgrowth is necessary to achieve better long-term results.

Animals↗