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Biomedical subjects

P Palmieri

Publications and source records attributed to P Palmieri.

At least 19 recordsLinked to original sources
PubMed1996

[Multilocular cystic nephroma in children. Description of a case].

In paediatric age there may occur the various types of cystic renal tumor also of different clinical meaning; we can count among them shapes openly or potentially deadly, among which Wilms tumor cystic owing to haemorrhages and tumoral necrosis, congenital mesoblastic cystic nephroma, clear cell carcinoma, cystic, partially differentiated nephroblastoma (CPDN) and benign forms such as multilocular cystic nephroma (MLCN), cystic localized dysplasia of the kidney. In some cases, the differential diagnosis is difficult and it becomes only by histology: particularly the differential diagnosis between MLCN and CPDN, indistinguishable on the basis of the imaging and the macroscopic aspect, it is possible only by histology. It is described a case of multicystic lesion in a baby, male, aged twenty-two months, with an indolent mass of left side, screened by US and TC. The US examination has put into evidence the presence of renal with clean outlines of eight cms, formed by multiple small cysts, divided by thin regular septa . These aspects have been confirmed by TC. The histological examination has diagnosed a multilocular cystic nephroma, without atypias. Therefore, the multilocular cystic lesions of the kidney have to be considered potentially malignant and submitted to surgical treatment.

Diagnosis, Differential↗
PubMed1985

Evoked potentials in uremia: basal and follow-up data.

Various EPs have been employed to disclose even early-stage central and peripheral nervous system damage in uremia. This approach also gives the possibility to follow up alterations of many sensory functions during the sequential stages of uremia. Fifty-three subjects (35 male and 18 female, mean age 42.20 +/- 5.50 yrs, conventionally low nitrogen diet treated, on dialysis or transplanted) were followed-up by recording the EPs every year for seven years. The P100 wave latency and amplitude of VEPs were recorded and found abnormal in about 70% of the examined visual systems. The auditory EPs were abnormal in 53% of the cases for the peak latencies, interpeak times and peak ratios. The somatosensory EPs showed in 75% of the cases an altered latency and morphology of the waves registered in the lumbar, cervical and cranial loci. There is evidence suggesting that evoked cerebral biorhythms may provide sensitive and objective indexes of cerebral function in uremia. The persistence of abnormalities disclosed by EPs follow-up confirm the reliability of this technique in evaluating neuro-pathologic uremic situations and in supplying optimal uremia therapies.

Adult↗
PubMed1981

Endocrine function in four anencephalic infants.

Endocrine studies of 4 anencephalic infants were carried out. No hypothalamic or hypophyseal structures could be found in any of them macroscopically, but we cannot say that there were no functioning pituitary cells which might have been seen microscopically. A combined LH-RH and TRH test was performed in the 6th h of life, followed by an intravenous glucose tolerance test 1 h later. Our data suggest that: (1) adenohypophyseal tissue, present in anencephaly even in the absence of a hypothalamus, is able to synthesize PRL and TSH autonomously and, under specific stimulation, PRL, TSH, and ACTH can be released while FSH and LH-HCG are not, hGH secretion is doubtful; (2) the circulating hGH and TSH surges that normally occur after delivery are hypothalamus-dependent and do not occur in anencephalics; (3) the thyroid and adrenals are able to synthesize hormones when specifically stimulated, even in the absence of the hypothalamus, and (4) beta-pancreatic function is not markedly impaired in anencephaly.

Anencephaly↗
PubMed1980

Nuclear scattering radiography.

The quasi-elastic scattering of 1 GeV protons permits the three-dimensional reconstruction of the density distribution in extended bodies. Fast multiwire proportional chambers are used to localize the position of every incoming and outgoing charged particle and to determine the coordinates at the interaction vertex. This article describes tests on a human head fixed on formalin. The comparison with computed tomography scans and anatomical sections is encouraging. Slices with a volume element of 5.5 mm3 illustrate the sensitivity of the method. The results also demonstrate the ability of the method to select the density distribution of hydrogen by making use of the kinematic relations specific to elastic scattering. Trials of this method in living humans are being planned.

Brain↗
PubMed1978

Action of glutamic acid and of some glutamate analogues on the molluscan central neurones.

The effects of L-glutamic acid and of some glutamate analogues have been studied on the central nervous system of the snail Heobania vermiculata, using conventional electrophysiological techniques. The glutamate H-response had the mean equilibrium value of -(57 +/- 4) mV and was associated with a Cl- conductance change. The D-response to glutamate application showed an involvement of sodium ions. Aspartate was agonist of glutamate action and displayed similar equilibrium value of the H-response, whereas quisqualate H-response was 'non-invertible'.

Animals↗
PubMedDate not supplied

[IgA deficiency in pediatrics].

To evaluate the IgA deficiency we have considered 368 children, admitted to "Day hospital" for different pathologies: 64 of them had serum IgA levels lower than the normal values for their age according to Ellis and Robbin. The age of the children with this deficiency was included from 4 months up to 8 years: 39 were boys, 25 were girls. In 54 cases the IgA deficiency was "partial" that is: the IgA value found out was lower than the normal for the age, but higher than 5 mg%. In 10 cases the IgA deficiency was "severe" (the IgA value was lower than 5 mg%). Six cases, among the 29 ones with intestinal diseases, had a severe deficiency, whereas among the 22 cases with respiratory diseases 3 had a "severe" deficiency. The 2 patients with urinary disease had a partial deficiency; only one case of the remaining 11 with different pathologies had a "severe" deficiency. Among the carriers of serum IgA deficiency an high incidence of chronic pathology has been found out (83%). Nevertheless the percentage of IgA deficiency extrapolated from the all case histories doesn't differ very much (64 cases among 368 = 17.39%) considering only those patients with chronic relapsing pathology (53 cases among 275 = 18.2%). Therefore it seems that the IgA deficiency could be considered a chronicizing factor in the examinated pathology even if in few cases. Anyway the frequency of IgA deficiency has reached major values (29/54; 45.3%) in the patients with enteric diseases. The frequency of IgA deficiency is smaller but still important in those patients with respiratory diseases (22/64: 34.3%).(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗