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Biomedical subjects

P Pal

Publications and source records attributed to P Pal.

31 records · Page 2Linked to original sources
PubMed1989

High threshold aortic baroreceptors afferents in the sympathetic nerve of monkey.

A total of 25 afferent units were recorded in the thoracic sympathetic rami (T3-T4) localised at the base of the bracheocephalic trunk and the descending aorta. Two types of receptors, Type I and Type II, were found. Type I receptors, localised at the base of the bracheocaphalic trunk, were fast adapting and exhibited synchronous discharge with each systolic height of blood pressure and behaved like baroreceptors. There was no discharge at the diastolic phase of the cardiac cycle. These receptors also gave occasional single spike at each systolic height of pressure of about 90-120 mmHg. When the systemic pressure was increased from 120 to 180 mmHg due to occlusion of the descending aorta or intravenous administration of adrenaline, the frequency of discharge of Type I receptors increased and they behaved like the typical sino-aortic baroreceptors. Type II receptors, localised over the wall of the descending aorta, fired irregularly and they did not have any relation with heart beat and did not behave like baroreceptors. On the basis of the present observation it may be suggested that Type I receptors are high threshold baroreceptors which play a role in the homeostatic control during high blood pressure and that Type II receptors do not play such a role.

Animals↗
PubMed1985

High threshold aortic baroreceptor afferents in the sympathetic nerve.

In anaesthetized cats, 40 sympathetic sensory units in the bracheocephalic artery (30 units) and the descending aorta (10 units) were recorded by means of single-unit preparation. Direct evidence is available for the mechanosensitive nature of the receptors in the sympathetic afferents at the level of T3 and T4. Two distinct types of receptors were found (Type I and Type II). Type I receptors, which were fast adapting, gave a spike discharge at each systolic height of pressure (70-110 mmHg). However, they sometimes failed to appear even at such systolic pressure. When the systemic pressure was increased by occluding the descending aorta or by infusing adrenaline solution intravenously, the frequency of discharge of Type I receptors increased and they behaved much the same as the typical sinoaortic baroreceptors. Type II receptors were activated by mechanical probing and at high systemic pressure, though they did not fire always synchronously with heart beat. On the basis of the study it may be suggested that Type I receptors are high threshold baroreceptors and like other systemic baroreceptors, play a role in homeostatic control presumably in a state of high blood pressure, but on the other hand Type II receptors do not play such a role.

Animals↗
PubMed1984

Leopard syndrome.

Explore the source record for details and available documents.

Abnormalities, Multiple↗
PubMed1983

New arylsulfonylhydrazones of substituted benzaldehydes as anticancer agents.

Nineteen new arylsulfonylhydrazones of substituted benzaldehydes have been prepared. The antineoplastic activity of these compounds has been assessed against murine lymphocytic leukemia P-388 and Ehrlich ascites carcinoma (EAC). The compounds investigated have not reached the criteria of good antitumor activity. However, marginal activity in P-388 system has been exhibited by one of the tested derivatives, while two others have demonstrated mild anticancer activity against EAC.

Animals↗
PubMed1982

Visceral receptors and their afferents in the caudal mesenteric nerve of the duck.

1. The behaviour and reactivities of visceral receptors to different mechanical and chemical stimuli in simple unit preparations from the caudal mesenteric nerve of adult ducks were studied to examine the physiological roles of such receptors. 2. In total, 83 single unit activities were recorded from the caudal mesenteric nerve. 3. Receptors were grouped according to their locations in different layers of the rectum as (i) over the branching points of the blood vessel or in the serosal layer, (ii) in the muscle layer or (iii) in the mucous membrane of the rectum. 4. All the receptors, both spontaneous and non-spontaneous, responded to mechanical probing. Receptors of the muscle layer responded to distension also and showed a slowly-adapting nature. Most of the receptors of the other two groups were of the rapidly-adapting type. 5. Conduction velocity ranged from 0.76 to 34.6 m/s. 6. Sympathetic afferent fibres from the hind gut ascend along the intestinal nerve and join the caudal mesenteric nerve via the colonic ganglion.

Animals↗
PubMed1981

A study of some genetic markers among Ramgarhias, an artisan caste of Punjab.

156 males and 63 females belonging to the Ramgarhia community, an endogamous group of Punjab, were taken for the study of genetical markers like taste ability to PTC, mid digital hair and colourblindness, whereas 75 (50 males and 25 females) were tested for serum proteins. 71.70% males and 73.85% females were found to be tasters. The mid digital hair was absent in 67.34% of females and 64.74% of males. No female was found to be colourblind, however, 4.48% males were found having defective colourvision. The phenotypic frequencies of Hp 2--2, Hp 2--1 and Hp 1--1 were found to be 64.00%, 32.00% and 4.00%, respectively. No variant of transferrins and albumin was found.

Blood Proteins↗
PubMed1979

Ethnic diversity in Punjab as based on finger dermatoglyphics.

Four ethnic groups of Punjab having same dialect viz. Khatris, Jats, Brahmins and Muslims were taken to see ethnic differences in regards to the distribution of whorls, loops, and arches of finger dermatoglyphics. The results show that there is a great diversity in the four groups for these parameters. These groups were compared with similar ethnic groups of other places having different dialect. The results reveal that there seems to be ethnic affinity between the group known by same name and which is true for all the four groups.

Anthropology, Physical↗