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Biomedical subjects

P Pagano

Publications and source records attributed to P Pagano.

2 recordsLinked to original sources

A modelistic approach to evaluate the factors affecting the 137Cs transfer from mother to fetus in cattle.

The authors have analysed the relationship between 137Cs radioactivity and pregnancy in cattle with radiometric analysis of muscle, kidney and liver of 24 cattle at various stages of pregnancy, fed with fodder exposed to radioactive fall-out. Also the relative fetal muscle, kidney, liver and myocardium have been analysed. The automatic spectra analysis and the statistical one have given the following results: there is no correlation between 137Cs retention and the pregnancy stage in the cattle sampled; the absolute 137Cs concentration is always larger in the kidney than in the muscle (Km/Mm = 1.7), while it is just minor in minor in the liver (Lm/Mm = 0.8). The fetal concentration in muscle, kidney and liver is generally homogeneous, whereas the myocardium tends to retain more 137Cs in the first stages of the pregnancy as against the other tissues. In the last stage of pregnancy it presents a lower concentration. The authors have included the fetal body weight growth to get a more realistic description of the 137Cs transfer in the mother-fetus system; this approach enables to evaluate the kinetic constants so introduced.

Animals

Primary obstructed megaureter.

The clinical presentation and management of 57 primary obstructed megaureters in 46 patients, 35 of whom were children, are reported. Indications for operation include pain, infection, progressive pyelo-ureteric dilatation and reduction in the glomerular filtration rate. We have found that affected children cannot be managed successfully without operation. Conservative treatment may be employed effectively in adults in whom the condition is often stable and complications are less frequent. The preferred surgical technique is ureteric narrowing with reimplantation to the bladder by the Politano-Leadbetter method. The results of surgery are less satisfactory in adults than in children. This may be related to the reduced quantity of elastic tissue in the ureteric wall in adult cases.

Adult