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Biomedical subjects

P P Vancea

Publications and source records attributed to P P Vancea.

At least 19 recordsLinked to original sources
PubMed2005

[Considerations regarding Goldmann's rheologic equation].

PURPOSE: The aim of this paper is to verify if Goldmann's rheological concept is still valid. That is because the validity of this concept has been contested. (Beneyto P., Fernandez-Vila P.C., Perez T.M--An experimental approximation to the law of Goldmann: study of the dynamics of the aqueous humor outflow. Ann. Ophthalmol. Glaucoma, 1995, 27, 3, 160-166, Abstract in Glaucoma abstracts 1995, Vol. 6, nr. 3, 63.) MATERIAL: The authors sustained that Goldmann's equation has never been verified. On 42 normal eyes and 54 glaucomatous eyes (POAG) they determined aqueous flow by fluorophotometry, IOP by aplanotonometry and considered a value of 9mmHg as normal episcleral veins pressure. The results they obtained showed that in 47% of the cases the fluorophotometric values were with over 1microl/min higher then the calculated values using Goldmann's equation. So, they concluded that Goldmann's equation could be wrong. METHOD: There are two outflow pathways for the aqueous humor, trabecular and uveoscleral. Obviously, the uveoscleral outflow (Fu) summed with the trabecular outflow (Ftr) must be equal with the aqueous flow (FIN), and the total outflow facility (CTRU) must be the sum of the trabecular outflow facility (Ctr) and uveoscleral facility (Cu). Thereby Goldmann's equation can be written: FIN = Ftr + Fu = (Pio-Pv) * CTRU and Ftr = (Pio-Pv) * Ctr, Fu = (Pio-Pv) * Cu. With the authors' data we verified the previous equations. RESULTS: There is correspondence between clinical and mathematically deducted parameters. CONCLUSIONS: 1. Goldmann's rheological concept is still valid. 2. With proper modifications Goldmann's equation is still valid.

Algorithms↗
PubMed1998

[The effect of chronic beta-blocker treatment on the evolution of primary open-angle glaucoma].

UNLABELLED: Comparative analysis of the results of the trabeculectomy in primary open-angle glaucoma (POAG) when it was chosen as a primary treatment and when was preceded by chronic use of topic beta-blockers. MATERIAL AND METHOD: Retrospective study of 59 patients (group A) with primary trabeculectomy and 42 patients (group B) with topic beta-blockers treatment for at least 3 years subsequent to trabeculectomy was performed. The average postoperative follow-up period was 3 years and 5 months. RESULTS: Postoperative IOP lowering was similar in both groups; There are no statistical differences between group A and B concerning stationary cases (76.27% in group A and 75.4% in group B), regressive cases (6.8% and 7.14% respectively) and progressive cases (18.6% and 17.9% respectively); Preoperative and postoperative complication rates were similar in the 2 groups. CONCLUSIONS: The chronic beta-blockers use does not influence the evolution of operated POAG.

Adrenergic beta-Antagonists↗
PubMed1997

[Primary trabeculectomy for early-onset congenital glaucomas].

OBJECTIVE: Analysis of the results of primary trabeculectomy in the treatment of congenital glaucoma. MATERIALS AND METHOD: Retrospective study of a series of 62 patients with primary trabeculectomy for congenital glaucoma, with a mean follow-up period of 2.22+/-2.86 years. RESULTS: The last controlled intraocular pressure (IOP) was higher for the patients in the age group 0-1 year (16.9+/-8) as compared with the patients older than 1 year (14.9+/-7). An intraocular pressure < or = 20 mmHg without additional medication has been found in 58.3% of the cases in the 0-1 year age group, versus 65.8% in the group of patients older than 1 year. The number of reoperations was higher in the 0-1 year age group (14), as compared with the group of patients older than 1 year (8). The rate of qualified therapeutic success (IOP < or = 20 mmHg) was 79.1% in the 0-1 year age group, versus 85.5% in the group of patients older than 1 year. CONCLUSIONS: Primary trabeculectomy is effective in the treatment of congenital glaucoma. The poorer results in the group of patients under 1 year of age is correlated with disease severity. The rate of favorable results is increased by reoperation, the majority of surgical failures belonging to the group of patients who needed reoperations.

Age of Onset↗
PubMed1997

[Primary trabeculectomy in the surgery of primary open angle glaucoma].

OBJECTIVE: Comparative analysis of the results of trabeculectomy in the surgery of primary open angle glaucoma (POAG) as the primary therapeutical approach and after the medical treatment failure. MATERIALS AND METHOD: Retrospective study including two therapeutical groups: A (59 patients) with primary trabeculectomy; and B (60 patients) with trabeculectomy following a medical treatment failure; mean follow-up period was 3 years and 5 months. RESULTS: Postoperative drop in intraocular pressure was similar in the two groups; there is no statistical significant difference between the two groups regarding stationary disease (76.27% in group A, versus 73.33% in group B), regressive disease (6.8% versus 6.7% respectively) and progressive disease (18.6% in group A, versus 21.6% in group B). At an intraocular pressure < or = 21 mmHg 13.6% of glaucoma cases do progress. The rate of peroperative and postoperative complications is similar in the two groups. CONCLUSIONS: The prior medical treatment of glaucoma doesn't affect the evolution of operated POAG. Primary trabeculectomy is indicated for non-compliant patients and for patients in whom administration of combined medical treatment for short time periods doesn't lower the intraocular pressure at safe levels. Surgical treatment has the advantage of an important and constant lowering of the intraocular pressure which is an absolute requirement for an efficient control of advanced glaucoma.

Aged↗
PubMed1979

Lamellar keratoplasty in keratoconus.

The authors present the results of 11 keratoplasties in cases of keratoconus, comparing the visual acuity and the ocular refraction before and after the operation (ophtalmometry, objective and subjective refractometry). The statistical data indicate a meaningful flattening of the corneal curvature (12.84 dpt average) and a mean reduction of the myopia for 8.227 dpt. In fact, the basic regular astigmatism of the cornea had not been altered. The mean visual acuity was 0.68 (with an improvement of 0.495). No further damage of acuity had been observed. After 10 to 69 months a medical checkup revealed transparent grafts in five cases; four presented small maculae; one, thin folds of Descemet's membrane. Based on the authors' experience and on the literature, the paper recommends lamellar keratoplasty in cases of keratoconus, the surgeon must choose the appropriate moment in the course of the development of this disease.

Adult↗
PubMed1979

[34 epibulbar malignant tumours (author's transl)].

Based on a study of 34 cases, the authors make therapeutical and diagnostical references concerning the epibulbar malignant tumours. These were met with a frequency of 10% of the total amount of the malignant tumours of the visual apparatus. The most frequent setting were at the level of the bulbar conjunctiva and of the sclero-corneal limb, especially in front of the opening of the palpebral slit and in the temporal area. The histological examination of the tumours pointed out the following morphological types; epitheliomas (61%), especially spino-cellular, malignant melanomas (32%) and sarcomas (6%). The therapeutical attitude was the surgical one -- the accurate extirpation -- in the limited tumours, followed by radiotherapy when neoplasic lesions were found at the limit of section. In the invaded tumours, the exenteration of the orbit was performed followed by radiotherapy. On the terms of such a therapeutical conduct, the distant prognosis proved to be dependent on two factors: a. The early diagnosis, that is the stage of the therapeutical action. It is insisted upon the importance of the signs of malignization of some benign tumors: papillomas or naevi. b. The nature and origin of the tumour: the secondary tumours are more severe from the beginning.

Adolescent↗
PubMed1978

[Diagnostic and therapeutic problems in a clinical case of oculoauricular dysplasia associated with mandibule-facial dysostosis (Franceschetti-Goldenhar syndrome)].

The authors present a case of oculo-auricular dysplasia (type Goldenhar) associated with France-schetti's syndrome (mandibulo-facial dysostosis) and complicated by paralytic strabismus and genital malformations. Complete investigation failed to establish a precise aetiology; one suggests an external disturbance in the course of the organogenesis of the branchial arches. Aesthetic improvement was undertaken--removal of epibulbar dermoids, correction of the squint, and ablation of the preauricular appendages; functional orthodontic treatment continues.

Adult↗
PubMed1977

On the individual pressure tolerance of the glaucomatous eye.

The individual pressure tolerance of any eye can be determined by taking account of the age, the values of the mean arterial pressure APm, the C/D ratio and the degree of deterioration of the visual field. The method developed opens the way to new possibilities in anti-glaucomatous therapy by making it possible to know the value of the maximum pressure (IPT) which can be supported by the eye under treatment. That treatment must succeed in reducing the value Pi to below the value IPT, if it is to be hoped that the evolution of the glaucoma will be stopped.

Blood Pressure↗
PubMed1977

[Considerations of malignant ocular tumours in children (author's transl)].

The authors undertake a clinico-anatomical study of 27 malignant tumours of the orbit and eye in children seen at the Ophthalmological Clinic in Jassy over the last 12 years. The majority (18 cases) were intra-ocular tumours which were clinically and anatomically retinoblastomas. After presenting the clinical symptoms, drawing attention to the signs of the disease presenting to paediatricians, the treatment is described. This was surgical in all cases followed by radiotherapy according to the case. Analysis of fatal cases and those which survived demonstrate certain degrees of seriousness in clinical, histopathological and therapeutic aspects. It can be appreciated that the long-term prognosis of these cases depends on the early diagnosis and the institution of the correct treatment as well as the anatomopathological form.

Adolescent↗