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Biomedical subjects

P P Leonello

Publications and source records attributed to P P Leonello.

10 recordsLinked to original sources

Thermography.

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Humans↗

Compliance with anticoagulant drug therapy: a study on patients with prosthetic heart valves.

The compliance to anticoagulants of a group of patients with prosthetic heart valves has been assessed in the present study. It was found that the level of compliance to these agents was of the order of 90%. Additional compliance data were generated in relation to cardiac drugs and diuretics, which were taken concurrently by the patients. Significant differences were noted between the three categories, the diuretics being the group for which compliance was least. It is postulated that the formal routine adopted by clinics managing patients on anticoagulants greatly enhances compliance with these drugs. The inconvenience of the mode of action of diuretics is no doubt a significant factor in the poor compliance found with them.

Adult↗

Atenolol in hypertension: follow-up of patients crossed over to this agent from propranolol, pindolol or metoprolol.

Thirty hypertensive patients treated with a drug regimen which contained a beta-receptor antagonist (either propranolol, pindolol or metoprolol) exhibited an improvement in blood pressure control when atenolol was substituted for the corresponding beta-blocker in the drug regimen. Additional benefits noted were a reduction in concomitant drug therapy and an improvement in reported side effects. Atenolol caused a significant decrease in heart rate in the group for which the mean follow-up period was 23.6 months.

Adult↗

Pindolol in orthostatic hypotension: possible therapy?

The association of recumbent hypertension with orthostatic hypotension provides a clinical situation which is extremely difficult to treat. The present report describes two patients who presented with this disorder and evaluates the use of pindolol in their management.

Humans↗

Hypertension after ingestion of Trimolets.

A 21-year-old nurse presented with severe headache after ingesting one phenylpropanolamine (Trimolets) tablet. Examination revealed hypertension. Although no specific therapy was administered to the patient, her blood pressure normalized within a few hours of admission to hospital and has remained normal since. The patient declined rechallenge with the suspected drug.

Adult↗